Search Results - "Wolfgang, W J"

Combinational approach of intrabody with enhanced Hsp70 expression addresses multiple pathologies in a fly model of Huntington's disease by McLear, J.A, Lebrecht, D, Messer, A, Wolfgang, W.J

“…Intracellular antibodies (intrabodies) and the chaperone, heat shock protein 70 (Hsp70), have each shown potential as therapeutics for neurodegenerative…”
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Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein by Blachly-Dyson, E, Song, J, Wolfgang, W J, Colombini, M, Forte, M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A genetic basis for the variable effect of smoking/nicotine on Parkinson’s disease by Hill-Burns, E M, Singh, N, Ganguly, P, Hamza, T H, Montimurro, J, Kay, D M, Yearout, D, Sheehan, P, Frodey, K, Mclear, J A, Feany, M B, Hanes, S D, Wolfgang, W J, Zabetian, C P, Factor, S A, Payami, H

“…Prior studies have established an inverse association between cigarette smoking and the risk of developing Parkinson’s disease (PD), and currently, the…”
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Cystamine and intrabody co-treatment confers additional benefits in a fly model of Huntington's disease by Bortvedt, S.F, McLear, J.A, Messer, A, Ahern-Rindell, A.J, Wolfgang, W.J

“…Abstract Huntington's disease (HD) is a lethal, neurodegenerative disorder caused by expansion of the polyglutamine repeat in the Huntingtin gene ( HTT ),…”
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Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster by Demchyshyn, L.L, Pristupa, Z.B, Sugamori, K.S, Barker, E.L, Blakely, R.D, Wolfgang, W.J, Forte, M.A, Niznik, H.B

“…We report here on the isolation and characterization of a serotonin (5HT) transporter from Drosophila melanogaster. A 3.1-kb complementary DNA done (dSERT) was…”
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Accuracy of Five On-Site Immunoassay Drugs-of-Abuse Testing Devices by Taylor, E. Howard, Oertli, Ernest H., Wolfgang, Jana W., Mueller, Eric

“…Many current “on-site” urine drug-testing products claim performance equivalent to laboratory testing. Five commercially available products (PharmScreen™,…”
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The Drosophila gene coding for the alpha subunit of a stimulatory G protein is preferentially expressed in the nervous system by Quan, F, Wolfgang, W.J, Forte, M.A

“…In mammals, the α subunit of the stimulatory guanine nucleotide-binding protein (Gsα ) functions to couple a variety of extracellular membrane receptors to…”
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A Drosophila G-Protein α Subunit, Gfα, Expressed in a Spatially and Temporally Restricted Pattern During Drosophila Development by Quan, Franklin, Wolfgang, William J., Forte, Michael

“…Heterotrimeric guanine nucleotide binding proteins (G proteins) couple receptors for extracellular signals to intracellular second messenger-generating…”
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Larval cuticular morphogenesis in the tobacco hornworm, Manduca sexta, and its hormonal regulation by Wolfgang, William J., Riddiford, Lynn M.

“…The sequential synthesis and deposition of larval cuticular proteins was followed during the final larval molt and the final larval instar of the tobacco…”
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Posterior localization of the Drosophila Gi alpha protein during early embryogenesis requires a subset of the posterior group genes by Wolfgang, W J, Forte, M

“…Shortly after fertilization in Drosophila embryos, the G-protein alpha subunit, Gi alpha, undergoes a dramatic redistribution. Initially granules containing Gi…”
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Immunolocalization of G protein alpha-subunits in the Drosophila CNS by Wolfgang, WJ, Quan, F, Goldsmith, P, Unson, C, Spiegel, A, Forte, M

“…In order to uncover the role of G proteins in the integrative functioning and development of the nervous system, we have begun a multidisciplinary study of the…”
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Cuticular mechanics during larval development of the tobacco hornworm, Manduca sexta by WOLFGANG, W. J, RIDDIFORD, L. M

“…Tensile properties of the larval cuticle of Manduca sexta were measured during the fifth instar. It was found that as the larvae grew and the cuticle…”
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The Pupal Cuticle of Drosophila: Differential Ultrastructural Immunolocalization of Cuticle Proteins by Wolfgang, William J., Fristrom, Dianne, Fristrom, James W.

“…Precise ultrastructural localization of Drosophila melanogaster pupal cuticle proteins (PCPs) was achieved by the immunogold labeling of frozen thin sections…”
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Modulation of the Light Response by cAMP in Drosophila Photoreceptors by Chyb, Sylwester, Hevers, Wulf, Forte, Michael, Wolfgang, William J, Selinger, Zvi, Hardie, Roger C

“…Phototransduction in Drosophila is mediated by a G-protein-coupled phospholipase C transduction cascade in which each absorbed photon generates a discrete…”
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Expression of acetylcholinesterase during visual system development in Drosophila by Wolfgang, William J., Forte, Micháel A.

“…As in other insects acetylcholine (ACh) and acetylcholinesterase (AChE) function in synaptic transmission in the central nervous system of Drosophila. Studies…”
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Signaling through Gsα is required for the growth and function of neuromuscular synapses in Drosophila by Wolfgang, William J, Clay, Catherine, Parker, Jacqueline, Delgado, Ricardo, Labarca, Pedro, Kidokoro, Yoshiaki, Forte, Michael

“…Although synapses are assembled in a highly regulated fashion, synapses once formed are not static structures but continue to expand and retract throughout the…”
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Presynaptic Impairment of Synaptic Transmission in Drosophila Embryos Lacking Gsα by Hou, Dongmei, Suzuki, Kazuhiro, Wolfgang, William J., Clay, Catherine, Forte, Michael, Kidokoro, Yoshiaki

“…Gsα is a subunit of the heterotrimeric G-protein complex, expressed ubiquitously in all types of cells, including neurons. Drosophila larvae, which have…”
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Genetic Analysis of the Drosophila Gsα Gene by Wolfgang, William J, Hoskote, Ashwini, Roberts, Ian J H, Jackson, Shannon, Forte, Michael

“…Abstract One of the best understood signal transduction pathways activated by receptors containing seven transmembrane domains involves activation of…”
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An assembly zone antigen of the insect cuticle by Wolfgang, W J, Fristrom, D, Fristrom, J W

“…The assembly zone is a morphologically distinct region in the insect integument that lies between the epidermis and its principal secretory product, the…”
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Immunological and molecular characterization of G0α-like proteins in the Drosophila central nervous system by THAMBI, N. C, QUAN, F, WOLFGANG, W. J, SPIEGEL, A, FORTE, M

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