Search Results - "Wolff, S P"

Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose by Hunt, J. V., Smith, C. C., Wolff, S. P.

“…Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. J V Hunt , C C Smith and S P Wolff…”
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Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes by Wolff, S P, Dean, R T

“…Monosaccharide autoxidation (a transition metal-catalysed process that generates H2O2 and ketoaldehydes) appears to contribute to protein modification by…”
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Protein glycation and oxidative stress in diabetes mellitus and ageing by Wolff, S P, Jiang, Z Y, Hunt, J V

“…Hyperglycemia is increasingly regarded as the cause of the diabetic complications, in particular via the ability of glucose to glycate proteins and generate…”
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Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant? by Ou, Peimian, Tritschler, Hans J., Wolff, Simon P.

“…Thioctic (α-lipoic) acid (TA) is a drug used for the treatment of diabetic polyneuropathy in Germany. It has been proposed that TA acts as an antioxidant and…”
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Elevated levels of authentic plasma hydroperoxides in NIDDM by Nourooz-Zadeh, J., Tajaddini-Sarmadi, J., McCarthy, S., Betteridge, D. J., Wolff, S. P.

“…Elevated levels of authentic plasma hydroperoxides in NIDDM. J Nourooz-Zadeh , J Tajaddini-Sarmadi , S McCarthy , D J Betteridge and S P Wolff Department of…”
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Lipid hydroperoxide measurement by oxidation of Fe2+ in the presence of xylenol orange. Comparison with the TBA assay and an iodometric method by Jiang, Zhen‐Yue, Woollard, Alison C. S., Wolff, Simon P.

“…Study of the role of hydroperoxides and lipid peroxidation in disease requires simple and sensitive methods for direct hydroperoxide measurement. We report on…”
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Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications by Wolff, S P

“…Diabetes mellitus is a syndrome initially characterized by a loss of glucose homeostasis. The disease is progressive and is associated with high risk of…”
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Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing by Hunt, J.V, Dean, R.T, Wolff, S.P

“…Protein exposed to glucose is cleaved, undergoes conformational change and develops fluorescent adducts ('glycofluorophores'). These changes are presumed to…”
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Hydrogen peroxide production during experimental protein glycation by Jiang, Zhen-Yue, Woollard, Alison C.S., Wolff, Simon P.

“…The accumulation of hydrogen peroxide (H 2O 2) during incubations of protein with glucose (experimental glycation) has previously been too low for direct…”
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Aminoguanidine: a drug proposed for prophylaxis in diabetes inhibits catalase and generates hydrogen peroxide in vitro by Ou, P, Wolff, S P

“…Aminoguanidine (AG) has been proposed as a drug of potential benefit in prophylaxis of the complications of diabetes. We show here that AG irreversibly…”
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Hydroperoxides in plasma are reduced by intensified insulin treatment. A randomized controlled study of IDDM patients with microalbuminuria by TORE JULSRUD BERG, NOUROOZ-ZADEH, J, WOLFF, S. P, TRITSCHLER, H. J, BANGSTAD, H.-J, HANSSEN, K. E

“…Hydroperoxides in plasma are reduced by intensified insulin treatment. A randomized controlled study of IDDM patients with microalbuminuria. T J Berg , J…”
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Erythrocyte catalase inactivation (H2O2 production) by ascorbic acid and glucose in the presence of aminotriazole: role of transition metals and relevance to diabetes by Ou, P, Wolff, S P

“…Erythrocytes exposed to ascorbic acid in the presence of aminotriazole undergo a dose- and time-dependent inactivation of endogenous catalase which is…”
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Plasma 8‐epi‐PGF2α levels are elevated in individuals with non‐insulin dependent diabetes mellitus by Gopaul, N.K., Änggård, E.E., Mallet, A.I., Betteridge, D.J., Wolff, S.P., Nourooz-Zadeh, J.

“…This study reports plasma levels of a specific nonenzymatic peroxidation product of arachidonic acid, esterified 8‐epi‐PGF2α, from healthy‐ and NIDDM…”
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Restoring good manners by Wolff, S P

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Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine by Nourooz-Zadeh, J, Tajaddini-Sarmadi, J, Wolff, S P

“…We describe the application of the FOX2 (ferrous oxidation in xylenol orange, version 2) method to the measurement of hydroperoxides in plasma. Authentic…”
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Hypothesis: UK consumption of dietary lipid hydroperoxides — a possible contributory factor to atherosclerosis by Wolff, Simon P., Nourooz-Zadeh, Jaffar

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Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein by Jiang, Z Y, Hunt, J V, Wolff, S P

“…A simple and sensitive method for the direct measurement of lipid peroxides in lipoprotein and liposomes is described. The method is based on the principle of…”
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Archaeology as Intellectual Service: Engaged Archaeology in San Pasquale Valley, Calabria, Italy by Chesson, Meredith S., Ullah, Isaac I. T., Iiriti, Giovanni, Forbes, Hamish, Lazrus, Paula K., Ames, Nicholas, Garcia, Yesenia, Benchekroun, Sarah, Robb, John, Wolff, Nicholas P. S., Squillaci, Maria Olimpia

“…Based on recent research in the San Pasquale Valley in southern Calabria, this paper presents our experiences with combining ethnographic and traditional…”
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Correlation between car ownership and leukaemia: is non-occupational exposure to benzene from petrol and motor vehicle exhaust a causative factor in leukaemia and lymphoma? by Wolff, S P

“…Although there is widespread agreement that many cancers have environmental causes we are often unable to see associations between specific cancers and…”
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α-lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria by Borcea, Valentin, Nourooz-Zadeh, Jaffar, Wolff, Simon P, Klevesath, Martina, Hofmann, Marion, Urich, Heinz, Wahl, Peter, Ziegler, Reinhard, Tritschler, Hans, Halliwell, Barry, Nawroth, Peter P

“…In the present cross-sectional study, the influence of α-lipoic acid on markers of oxidative stress, assessed by measurement of plasma lipid hydroperoxides…”
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