Search Results - "Wolff, Johannes"

Anemia in Placebo Arms of Cancer Studies by WOLFF, JOHANNES E.

“…Background/Aim: Adverse event (AE) frequencies observed in interventional clinical trials are difficult to interpret when the placebo control is missing…”
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Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone by Rutkowski, Stefan, Bode, Udo, Deinlein, Frank, Ottensmeier, Holger, Warmuth-Metz, Monika, Soerensen, Niels, Graf, Norbert, Emser, Angela, Pietsch, Torsten, Wolff, Johannes E.A, Kortmann, Rolf D, Kuehl, Joachim

“…Medulloblastoma in young children has a poor prognosis. Furthermore, cognitive function in survivors is often impaired owing to treatment with cranial…”
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Extended Versus Limited Lymph Node Dissection in Bladder Cancer Patients Undergoing Radical Cystectomy: Survival Results from a Prospective, Randomized Trial by Gschwend, Jürgen E., Heck, Matthias M., Lehmann, Jan, Rübben, Herbert, Albers, Peter, Wolff, Johannes M., Frohneberg, Detlef, de Geeter, Patrick, Heidenreich, Axel, Kälble, Tilman, Stöckle, Michael, Schnöller, Thomas, Stenzl, Arnulf, Müller, Markus, Truss, Michael, Roth, Stephan, Liehr, Uwe-Bernd, Leißner, Joachim, Bregenzer, Thomas, Retz, Margitta

“…The extent of lymph node dissection (LND) in bladder cancer (BCa) patients at the time of radical cystectomy may affect oncologic outcome. To evaluate whether…”
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Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011 by Ostrom, Quinn T, de Blank, Peter M, Kruchko, Carol, Petersen, Claire M, Liao, Peter, Finlay, Jonathan L, Stearns, Duncan S, Wolff, Johannes E, Wolinsky, Yingli, Letterio, John J, Barnholtz-Sloan, Jill S

“…The CBTRUS Statistical Report: Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United…”
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American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012 by Ostrom, Quinn T, Gittleman, Haley, de Blank, Peter M, Finlay, Jonathan L, Gurney, James G, McKean-Cowdin, Roberta, Stearns, Duncan S, Wolff, Johannes E, Liu, Max, Wolinsky, Yingli, Kruchko, Carol, Barnholtz-Sloan, Jill S

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Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children by Thomas, Christian, Ruland, Vincent, Kordes, Uwe, Hartung, Stefan, Capper, David, Pietsch, Torsten, Gerß, Joachim, Wolff, Johannes E. A., Paulus, Werner, Hasselblatt, Martin

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Intensive chemotherapy improves survival in pediatric high‐grade glioma after gross total resection: results of the HIT‐GBM‐C protocol by Wolff, Johannes E.A., Driever, Pablo Hernaiz, Erdlenbruch, Bernhard, Kortmann, Rolf D., Rutkowski, Stefan, Pietsch, Torsten, Parker, Crystal, Metz, Monica Warmuth, Gnekow, Astrid, Kramm, Christof M.

“…BACKGROUND: The authors hypothesized that intensified chemotherapy in protocol HIT‐GBM‐C would increase survival of pediatric patients with high‐grade glioma…”
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Fatigue in Cancer Treatment Studies: Analysis of Placebo Arms by Hauch, Holger, Wolff, Birte J, Wolff, Johannes E

“…Fatigue and asthenia are common in patients with cancer; and identifying the cause as drug toxicity versus cancer progression is difficult, particularly in…”
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Atypical choroid plexus papilloma: clinical experience in the CPT-SIOP-2000 study by Wrede, Brigitte, Hasselblatt, Martin, Peters, Ove, Thall, Peter F., Kutluk, Tezer, Moghrabi, Albert, Mahajan, Anita, Rutkowski, Stefan, Diez, Blanca, Wang, Xuemei, Pietsch, Torsten, Kortmann, Rolf-Dieter, Paulus, Werner, Jeibmann, Astrid, Wolff, Johannes E. A.

“…Atypical choroid plexus papilloma (APP) represents a novel intermediate-grade subtype of choroid plexus tumor (CPT), the clinical outcome of which has not been…”
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A phase 1 study of the pan‐bromodomain and extraterminal inhibitor mivebresib (ABBV‐075) alone or in combination with venetoclax in patients with relapsed/refractory acute myeloid leukemia by Borthakur, Gautam, Odenike, Olatoyosi, Aldoss, Ibrahim, Rizzieri, David A., Prebet, Thomas, Chen, Chris, Popovic, Relja, Modi, Dimple A., Joshi, Rujuta H., Wolff, Johannes E., Jonas, Brian A.

“…Background Acute myeloid leukemia (AML) is a heterogenous malignancy driven by genetic and epigenetic factors. Inhibition of bromodomain and extraterminal…”
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Treatment of children under 4 years of age with medulloblastoma and ependymoma in the HIT2000/HIT-REZ 2005 trials: Neuropsychological outcome 5 years after treatment by Ottensmeier, Holger, Schlegel, Paul G, Eyrich, Matthias, Wolff, Johannes E, Juhnke, Björn-Ole, von Hoff, Katja, Frahsek, Stefanie, Schmidt, Rene, Faldum, Andreas, Fleischhack, Gudrun, von Bueren, Andre, Friedrich, Carsten, Resch, Anika, Warmuth-Metz, Monika, Krauss, Jürgen, Kortmann, Rolf D, Bode, Udo, Kühl, Joachim, Rutkowski, Stefan

“…Young children with brain tumours are at high risk of developing treatment-related sequelae. We aimed to assess neuropsychological outcomes 5 years after…”
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Postoperative Adjuvant Dendritic Cell–Based Immunotherapy in Patients with Relapsed Glioblastoma Multiforme by De Vleeschouwer, Steven, Fieuws, Steffen, Rutkowski, Stefan, Van Calenbergh, Frank, Van Loon, Johannes, Goffin, Jan, Sciot, Raf, Wilms, Guido, Demaerel, Philippe, Warmuth-Metz, Monika, Soerensen, Niels, Wolff, Johannes E A, Wagner, Sabine, Kaempgen, Eckhart, Van Gool, Stefaan W

“…Purpose: To investigate the therapeutic role of adjuvant vaccination with autologous mature dendritic cells (DC) loaded with tumor lysates derived from…”
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Adverse Events in Placebo Arms of Cancer Trials by Wolff, Johannes E, Wolff, Birte J, Thielen, Marceal M, Hauch, Holger

“…Adverse events (AEs) in cancer trials may be caused by the investigational agents or the underlying disease. Determining the causality is challenging,…”
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How long can folinic acid rescue be delayed after high-dose methotrexate without toxicity? by Cohen, Ian Joseph, Wolff, Johannes E.

“…To determine the optimal time of folinic acid rescue after methotrexate (MTX) treatment in patients with ALL, we selected and evaluated relevant studies that…”
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Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: a systematic review and survival-gain analysis by Xu, Tao, Chen, Juxiang, Lu, Yicheng, Wolff, Johannes Ea

“…The combination of bevacizumab and irinotecan is a new chemotherapy protocol increasingly used for recurrent malignant glioma. Results from phase II trials…”
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Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis by Ruland, Vincent, Hartung, Stefan, Kordes, Uwe, Wolff, Johannes E., Paulus, Werner, Hasselblatt, Martin

“…Choroid plexus carcinoma is a malignant brain tumor predominantly occurring in young children. Only limited data are available regarding the underlying…”
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Intermittent hormonal therapy in the treatment of metastatic prostate cancer: a randomized trial by Mottet, Nicolas, Van Damme, Jean, Loulidi, Salim, Russel, Christoph, Leitenberger, Armin, Wolff, Johannes M.

“…Study Type – Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Intermittent androgen deprivation therapy (ADT)…”
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Etoposide improves survival in high-grade glioma: a meta-analysis by Leonard, Alexis, Wolff, Johannes E

“…The purpose of this meta-analysis was to evaluate the therapeutic efficacy of topoisomerase inhibitors in the treatment of high-grade gliomas (HGGs). Using…”
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Adjuvant dendritic cell-based tumour vaccination for children with malignant brain tumours by Ardon, Hilko, De Vleeschouwer, Steven, Van Calenbergh, Frank, Claes, Laurence, Kramm, Christof M., Rutkowski, Stefan, Wolff, Johannes E.A., Van Gool, Stefaan W.

“…Background A large experience with dendritic cell (DC)‐based vaccination for malignant brain tumours has been gained in adults. Here we focus on the results…”
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Headache Reporting in Oncology Trials Depends on the Demographics of the Study Population by WOLFF, BIRTE J., WOLFF, MATTHAEUS J., WOLFF, JOHANNES E.

“…BACKGROUND/AIMThe frequency of adverse events (AEs) in clinical trials without control arms is difficult to interpret. MATERIALS AND METHODSThis is a…”
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