Search Results - "Wolff, Horst"
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In vitro structure-toxicity relationship of chalcones in human hepatic stellate cells
Published in Toxicology (Amsterdam) (02-10-2015)“…Abstract Xanthohumol (XN), the major prenylated chalcone from hops ( Humulus lupulus L.), has received much attention within the last years, due to its…”
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Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus
Published in Virus research (01-08-2005)“…The availability of highly active antiretroviral therapies (HAART) has not eliminated HIV-1 infection of the central nervous system (CNS) or the occurrence of…”
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3
Aqueous extracts of the marine brown alga Lobophora variegata inhibit HIV-1 infection at the level of virus entry into cells
Published in PloS one (21-08-2014)“…In recent years, marine algae have emerged as a rich and promising source of molecules with potent activities against various human pathogens. The widely…”
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4
EASY-HIT: HIV Full-Replication Technology for Broad Discovery of Multiple Classes of HIV Inhibitors
Published in Antimicrobial Agents and Chemotherapy (01-12-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
Long-term HIV-1 infection of neural progenitor populations
Published in AIDS (London) (12-11-2007)“…HIV can reside in the brain for many years. While astrocytes are known to tolerate long-term HIV infection, the potential of other neural cell types to harbour…”
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6
Identification of a Heterogeneous Nuclear Ribonucleoprotein-recognition Region in the HIV Rev Protein
Published in The Journal of biological chemistry (27-11-2009)“…The Rev protein is a key regulator of human immunodeficiency virus type 1 (HIV-1) gene expression. Rev is primarily known as an adaptor protein for nuclear…”
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7
High content analysis with AxioVision ASSAYbuilder: applications in pharmaceutical biology
Published in BioTechniques (01-05-2008)Get full text
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8
Progress in live-cell imaging and screening applications using Definite Focus
Published in BioTechniques (01-11-2009)Get full text
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9
Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters
Published in Chromosome research (01-06-2010)“…A new experimental approach was designed to test different predictions of current models of the nuclear architecture with respect to the topography of…”
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The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation
Published in Human molecular genetics (01-08-2004)“…YT521-B is a ubiquitously expressed nuclear protein that changes alternative splice site usage in a concentration dependent manner. YT521-B is located in a…”
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11
Activation of a HERV-H LTR induces expression of an aberrant calbindin protein in human prostate carcinoma cells
Published in Retrovirology (24-09-2009)“…Doc number: P48…”
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12
A suicide gene approach using the human pro-apoptotic protein tBid inhibits HIV-1 replication
Published in BMC biotechnology (11-01-2011)“…Regulated expression of suicide genes is a powerful tool to eliminate specific subsets of cells and will find widespread usage in both basic and applied…”
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Live-cell assay for simultaneous monitoring of expression and interaction of proteins
Published in BioTechniques (01-12-2006)Get full text
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14
High-content analysis with AxioVision ASSAYbuilder
Published in Nature methods (01-05-2008)“…In drug discovery, and in biological experimentation in general, cell-based assays are replacing conventional in vitro binding or enzyme assays more and more…”
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15
Xanthohumol Uptake and Intracellular Kinetics in Hepatocytes, Hepatic Stellate Cells, and Intestinal Cells
Published in Journal of agricultural and food chemistry (28-12-2011)“…Xanthohumol (XN) is the major prenylated chalcone of hops and hence an ingredient of beer. Despite many advances in understanding of the pharmacology of XN,…”
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16
Did viral disease of humans wipe out the Neandertals?
Published in Medical hypotheses (01-07-2010)“…Summary Neandertals were an anatomically distinct hominoid species inhabiting a vast geographical area ranging from Portugal to western Siberia and from…”
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Influence of Hypericum perforatum extract and its single compounds on amyloid-β mediated toxicity in microglial cells
Published in Life sciences (1973) (23-08-2007)“…As immunocompetent cells of the brain, microglia are able to counteract the damaging effects of amyloid-β in Alzheimer's disease by phagocytosis-mediated…”
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Hyperforin is a modulator of inducible nitric oxide synthase and phagocytosis in microglia and macrophages
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-2010)“…Upon activation, microglia, the immunocompetent cells in the brain, get highly phagocytic and release pro-inflammatory mediators like nitric oxide (NO)…”
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19
Identification of a novel Rev-interacting cellular protein
Published in BMC cell biology (24-04-2005)“…Human cell types respond differently to infection by human immunodeficiency virus (HIV). Defining specific interactions between host cells and viral proteins…”
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HIV Full-Replication Technology for Identification of Novel HIV Inhibitors from Multiple Sources
Published in Antiviral research (01-05-2011)Get full text
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