Search Results - "Wolfer, D P"

Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment by Alboni, S, van Dijk, R M, Poggini, S, Milior, G, Perrotta, M, Drenth, T, Brunello, N, Wolfer, D P, Limatola, C, Amrein, I, Cirulli, F, Maggi, L, Branchi, I

“…Selective serotonin reuptake inhibitors (SSRIs) represent the most common treatment for major depression. However, their efficacy is variable and incomplete…”
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Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities by Wöhr, M, Orduz, D, Gregory, P, Moreno, H, Khan, U, Vörckel, K J, Wolfer, D P, Welzl, H, Gall, D, Schiffmann, S N, Schwaller, B

“…Gene mutations and gene copy number variants are associated with autism spectrum disorders (ASDs). Affected gene products are often part of signaling networks…”
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Cerebellar Ataxia and Purkinje Cell Dysfunction Caused by Ca2+-Activated K+Channel Deficiency by Sausbier, M., Hu, H., Arntz, C., Feil, S., Kamm, S., Adelsberger, H., Sausbier, U., Sailer, C. A., Feil, R., Hofmann, F., Korth, M., Shipston, M. J., H.-G. Knaus, Wolfer, D. P., Pedroarena, C. M., Storm, J. F., Ruth, P., Andersen, Per O.

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
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Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCage by Krackow, S., Vannoni, E., Codita, A., Mohammed, A. H., Cirulli, F., Branchi, I., Alleva, E., Reichelt, A., Willuweit, A., Voikar, V., Colacicco, G., Wolfer, D. P., Buschmann, J.‐U. F., Safi, K., Lipp, H.‐P.

“…The between‐laboratory effects on behavioral phenotypes and spatial learning performance of three strains of laboratory mice known for divergent behavioral…”
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Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members by Heber, Sabine, Herms, Jochen, Gajic, Vladan, Hainfellner, Johannes, Aguzzi, Adriano, Rulicke, Thomas, Kretzschmar, Hans, von Koch, Cornelia, Sisodia, Sangram, Tremml, Phillippe, Lipp, Hans-Peter, Wolfer, David P, Muller, Ulrike

“…The amyloid precursor protein (APP) involved in Alzheimer's disease is a member of a larger gene family including amyloid precursor-like proteins APLP1 and…”
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Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment? by Wolfer, David P., Lipp, Hans-Peter

“…Increasingly sophisticated and precise molecular genetic tools are applied to mice in order to study the cellular mechanisms underlying higher brain functions,…”
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Defective limbic system in mice lacking the tailless gene by Schütz, G, Monaghan, A. P, Bock, D, Gass, P, Schwger, A, Wolfer, D. P, Lipp, H.-P

“…The gene tailless is a member of the superfamily of genes that encode transcription factors of the ligand-activated nuclear receptor type, and is expressed in…”
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The impact of genetic background on neurodegeneration and behavior in seizured mice by Mohajeri, M. H., Madani, R., Saini, K., Lipp, H.‐P., Nitsch, R. M., Wolfer, D. P.

“…We used pilocarpine‐induced seizures in mice to determine the impact of genetic background on the vulnerability of hippocampal neurons and associated changes…”
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A role for the Ras signalling pathway in synaptic transmission and long-term memory by Klein, Rdiger, Brambilla, Riccardo, Gnesutta, Nerina, Minichiello, Liliana, White, Gail, Roylance, Alistair J, Herron, Caroline E, Ramsey, Mark, Wolfer, David P, Cestari, Vincenzo, Rossi-Arnaud, Clelia, Grant, Seth G. N, Chapman, Paul F, Lipp, Hans-Peter, Sturani, Emmapaola

“…Members of the Ras subfamily of small guanine-nucleotide-binding proteins are essential for controlling normal and malignant cell proliferation as well as cell…”
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No hippocampal neuron or synaptic bouton loss in learning-impaired aged β-Amyloid precursor protein-null mice by Phinney, A.L., Calhoun, M.E., Wolfer, D.P., Lipp, H.-P., Zheng, H., Jucker, M.

“…Aged β-amyloid precursor protein-null mice were used to investigate the relationship between β-amyloid precursor protein, hippocampal neuron and synaptic…”
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Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment by Alboni, S, van Dijk, R M, Poggini, S, Milior, G, Perrotta, M, Drenth, T, Brunello, N, Wolfer, D P, Limatola, C, Amrein, I, Cirulli, F, Maggi, L, Branchi, I

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Mice Lacking the Gene Encoding Tissue-Type Plasminogen Activator Show a Selective Interference with Late-Phase Long-Term Potentiation in Both Schaffer Collateral and Mossy Fiber Pathways by Huang, Yan-You, Bach, Mary Elizabeth, Lipp, Hans-Peter, Zhuo, Min, Wolfer, David P., Hawkins, Robert D., Schoonjans, Luc, Kandel, Eric R., Godfraind, Jean-Marie, Mulligan, Richard, Collen, D., Carmeliet, Peter

“…The gene encoding tissue-type plasminogen activator (t-PA) is an immediate response gene, downstream from CREB-1 and other constitutively expressed…”
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Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome by CHRAST, R, SCOTT, H. S, MADANI, R, HUBER, L, WOLFER, D. P, PRINZ, M, AGUZZI, A, LIPP, H.-P, ANTONARAKIS, S. E

“…The Drosophila single-minded (sim) transcription factor, is a master regulator of fruitfly neurogenesis. Recently, we have cloned and mapped a human homolog of…”
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mPer1 and mPer2 mutant mice show regular spatial and contextual learning in standardized tests for hippocampus-dependent learning by Zueger, M, Urani, A, Chourbaji, S, Zacher, C, Lipp, H P, Albrecht, U, Spanagel, R, Wolfer, D P, Gass, P

“…Learning and memory, like most physiological processes, seem to be under the control of circadian rhythm. The recently cloned mPer1 and mPer2 genes play an…”
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Testing cognitive navigation in unknown territories: homing pigeons choose different targets by Blaser, N, Dell'Omo, G, Dell'Ariccia, G, Wolfer, D P, Lipp, H-P

“…Homing pigeons (Columba livia) are believed to adopt a map-and-compass strategy to find their way home. Surprisingly, to date a clear demonstration of the use…”
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Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice by Pennanen, L., Wolfer, D. P., Nitsch, R. M., Götz, J.

“…The neuropathological hallmark shared between Alzheimer's disease (AD) and familial frontotemporal dementia (FTDP‐17) are neurofibrillary tangles (NFT) which…”
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The AP-1 Transcription Factor c-Jun Is Required for Efficient Axonal Regeneration by Raivich, Gennadij, Bohatschek, Marion, Da Costa, Clive, Iwata, Osuke, Galiano, Matthias, Hristova, Maria, Nateri, Abdolrahman S, Makwana, Milan, Riera-Sans, Lluı́s, Wolfer, David P, Lipp, Hans-Peter, Aguzzi, Adriano, Wagner, Erwin F, Behrens, Axel

“…Nerve injury triggers numerous changes in the injured neurons and surrounding nonneuronal cells that ultimately result in successful target reinnervation or…”
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Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified β-amyloid precursor protein gene by Tremml, Philippe, Lipp, Hans-Peter, Müller, Ulrike, Ricceri, Laura, P. Wolfer, David

“…The processing of β-amyloid precursor protein ( βAPP) and its metabolites plays an important role in the pathogenesis of Alzheimer’s disease (AD) and Down’s…”
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Comparative effects of exposure to an organophosphate pesticide on locomotor activity of laboratory mice and five species of wild rodents by DELL'OMO, G, PLESKACHEVA, M. G, WOLFER, D. P, LIPP, H.-P, SHORE, R. F

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The acallosal mouse strain I/LnJ: a putative model of ADHD? by Magara, Fulvio, Ricceri, Laura, Wolfer, David P, Lipp, Hans-Peter

“…ADHD has been sometimes associated to a defective interhemispheric cross-talk caused by hypoplasia of the corpus callosum. The inbred mouse strain I/LnJ shows…”
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