Search Results - "Wolfe, James F"
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Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones
Published in Journal of medicinal chemistry (01-01-1990)“…A series of 4(3H)-quinazolinones structurally related to 2-methyl-3-o-tolyl-4(3H)-quinazolinone (methaqualone, 3) were synthesized and evaluated for…”
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Synthesis and Evaluation of N-(Phenylacetyl)trifluoromethanesulfonamides as Anticonvulsant Agents
Published in Journal of medicinal chemistry (29-03-1996)“…A series of N-(phenylacetyl)trifluoromethanesulfonamides (3a − g) was prepared according to the Topliss scheme in order to determine if aryl substitutents…”
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Synthesis of 2H-1,2-Benzothiazine 1,1-Dioxides via Heteroannulation Reactions of 2-Iodobenzenesulfonamide with Ketone Enolates under SRN1 Conditions
Published in Journal of organic chemistry (11-11-2005)“…2-Iodobenzenesulfonamide (1a) underwent photostimulated SRN1 reactions in liquid NH3 with the potassium enolates derived from acetone, pinacolone, butanone,…”
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Synthesis and anticonvulsant evaluation of some new 2-substituted-3-arylpyrido[2,3- d]pyrimidinones
Published in Bioorganic & medicinal chemistry (01-11-2004)“…[Display omitted] A series of 2-substituted-3-arylpyrido[2,3- d]pyrimidinones was prepared for evaluation as potential anticonvulsants. In murine screening,…”
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Synthesis and anticonvulsant activity of 2-benzylglutarimides
Published in Journal of medicinal chemistry (01-03-1990)“…A series of 2-benzylglutarimides (4) and their N-methyl analogues (5) were prepared according to the Topliss scheme for the selection of benzyl substituents to…”
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Synthesis of Succinimido[3,4-b]indane and 1,2,3,4,5,6-Hexahydro-1,5-methano-3-benzazocine-2,4-dione by Sequential Alkylation and Intramolecular Arylation of Enolates Derived from N,N,N'N'-Tetramethylbutanediamides and N,N,N'N'-Tetramethylpentanediamides
Published in Journal of organic chemistry (05-03-1999)“…The tricyclic title compounds, 4 and 5, were synthesized by initial alkylation of the lithium monoenolates of N,N,N',N'-tetramethylbutanediamide (6) and…”
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Photostimulated Reactions of Phenylacetic Acid Dianions with Aryl Halides. Influence of the Metallic Cation on the Regiochemistry of Arylation
Published in Organic letters (24-08-2000)“…Phenylacetic acid dianions react via what appears to be an SRN1 process with aryl halides under photostimulation to afford aryl substitution products 5 and 6…”
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Synthesis of Succinimido[3,4-b]indane and 1,2,3,4,5,6-Hexahydro-1,5-methano-3-benzazocine-2,4-dione by Sequential Alkylation and Intramolecular Arylation of Enolates Derived from N,N,N ‘ N‘-Tetramethylbutanediamides and N,N,N ‘ N‘-Tetramethylpentanediamides
Published in Journal of organic chemistry (05-03-1999)“…The tricyclic title compounds, 4 and 5, were synthesized by initial alkylation of the lithium monoenolates of N,N,N ‘ ,N ‘-tetramethylbutanediamide (6) and…”
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Rigid-rod polymers. 1. Synthesis and thermal properties of para-aromatic polymers with 2,6-benzobisoxazole units in the main chain
Published in Macromolecules (01-07-1981)Get full text
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Solvent effects in heteroaromatic SRN1 reactions
Published in Journal of organic chemistry (01-11-1979)Get full text
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Metalation-carboxylation of p- and m-(trimethylsilyl)toluenes as a convenient route to [p- and m-(trimethylsilyl)phenyl]acetic acids
Published in Journal of organic chemistry (01-12-1980)Get full text
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Compatibility of Various Carbanion Nucleophiles with Heteroaromatic Nucleophilic Substitution by the SRN1 Mechanism
Published in Journal of organic chemistry (05-09-1997)“…Carbanions generated from 2,4,4-trimethyl-2-oxazoline (1a), 2-benzyl-4,4-dimethyl-2-oxazoline (1b), 2,4-dimethylthiazole (13a), 2-benzyl-4-methylthiazole…”
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Rigid-rod polymers. 2. Synthesis and thermal properties of para-aromatic polymers with 2,6-benzobisthiazole units in the main chain
Published in Macromolecules (01-07-1981)Get full text
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Chemistry of lithiotriphenylphosphineacetylmethylene
Published in Journal of organic chemistry (01-02-1976)Get full text
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Formation and reactions of dianions derived from 4-methylcarbostyril and trans-.beta.-methylcinnamanilide
Published in Journal of organic chemistry (01-11-1969)Get full text
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Synthesis and solution properties of extended chain poly(2,6-benzothiazole) and poly(2,5-benzoxazole)
Published in Macromolecules (01-09-1989)Get full text
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Alkali metal and electrochemical reductions of dibenzoylbenzenes
Published in Journal of organic chemistry (01-01-1974)Get full text
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Condensations at the Methyl Group of Ethyl Acetoacetate by Means of Potassium Amide or Sodium Hydride1
Published in Journal of organic chemistry (01-11-1964)Get full text
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Aromatic heteroannulation via metalation-cyclization of N-acyl-2-chlorobenzenesulfonamides and N-acylbenzenesulfonamides
Published in Journal of organic chemistry (01-09-1992)Get full text
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