Search Results - "Wolfe, James F"

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  1. 1

    Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones by Wolfe, James F, Rathman, Terry L, Sleevi, Mark C, Campbell, James A, Greenwood, Thomas D

    Published in Journal of medicinal chemistry (01-01-1990)
    “…A series of 4(3H)-quinazolinones structurally related to 2-methyl-3-o-tolyl-4(3H)-quinazolinone (methaqualone, 3) were synthesized and evaluated for…”
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    Journal Article
  2. 2

    Synthesis and Evaluation of N-(Phenylacetyl)trifluoromethanesulfonamides as Anticonvulsant Agents by Flaherty, Patrick T, Greenwood, Thomas D, Manheim, Amy L, Wolfe, James F

    Published in Journal of medicinal chemistry (29-03-1996)
    “…A series of N-(phenylacetyl)trifluoromethanesulfonamides (3a − g) was prepared according to the Topliss scheme in order to determine if aryl substitutents…”
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    Synthesis of 2H-1,2-Benzothiazine 1,1-Dioxides via Heteroannulation Reactions of 2-Iodobenzenesulfonamide with Ketone Enolates under SRN1 Conditions by Layman, William J, Greenwood, Thomas D, Downey, Aaron L, Wolfe, James F

    Published in Journal of organic chemistry (11-11-2005)
    “…2-Iodobenzenesulfonamide (1a) underwent photostimulated SRN1 reactions in liquid NH3 with the potassium enolates derived from acetone, pinacolone, butanone,…”
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    Journal Article
  4. 4

    Synthesis and anticonvulsant evaluation of some new 2-substituted-3-arylpyrido[2,3- d]pyrimidinones by White, David C., Greenwood, Thomas D., Downey, Aaron L., Bloomquist, Jeffrey R., Wolfe, James F.

    Published in Bioorganic & medicinal chemistry (01-11-2004)
    “…[Display omitted] A series of 2-substituted-3-arylpyrido[2,3- d]pyrimidinones was prepared for evaluation as potential anticonvulsants. In murine screening,…”
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    Synthesis and anticonvulsant activity of 2-benzylglutarimides by Goehring, R. Richard, Greenwood, Thomas D, Nwokogu, Godson C, Pisipati, Jyothi S, Rogers, Tommie G, Wolfe, James F

    Published in Journal of medicinal chemistry (01-03-1990)
    “…A series of 2-benzylglutarimides (4) and their N-methyl analogues (5) were prepared according to the Topliss scheme for the selection of benzyl substituents to…”
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    Photostimulated Reactions of Phenylacetic Acid Dianions with Aryl Halides. Influence of the Metallic Cation on the Regiochemistry of Arylation by Nwokogu, Godson C, Wong, Jim-Wah, Greenwood, Thomas D, Wolfe, James F

    Published in Organic letters (24-08-2000)
    “…Phenylacetic acid dianions react via what appears to be an SRN1 process with aryl halides under photostimulation to afford aryl substitution products 5 and 6…”
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    Compatibility of Various Carbanion Nucleophiles with Heteroaromatic Nucleophilic Substitution by the SRN1 Mechanism by Wong, Jim-Wah, Natalie, Kenneth J, Nwokogu, Godson C, Pisipati, Jyothi S, Flaherty, Patrick T, Greenwood, Thomas D, Wolfe, James F

    Published in Journal of organic chemistry (05-09-1997)
    “…Carbanions generated from 2,4,4-trimethyl-2-oxazoline (1a), 2-benzyl-4,4-dimethyl-2-oxazoline (1b), 2,4-dimethylthiazole (13a), 2-benzyl-4-methylthiazole…”
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