Search Results - "Wolfarth, Michael G."

Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes by Mercer, Robert R, Scabilloni, James F, Hubbs, Ann F, Battelli, Lori A, McKinney, Walter, Friend, Sherri, Wolfarth, Michael G, Andrew, Michael, Castranova, Vincent, Porter, Dale W

“…Prior studies have demonstrated a rapid and progressive acute phase response to bolus aspiration of multi-walled carbon nanotubes (MWCNTs). In this study we…”
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Pathologic and molecular profiling of rapid-onset fibrosis and inflammation induced by multi-walled carbon nanotubes by Dong, Jie, Porter, Dale W., Batteli, Lori A., Wolfarth, Michael G., Richardson, Diana L., Ma, Qiang

“…Multi-walled carbon nanotubes (MWCNT) are new materials with a wide range of industrial and commercial applications. However, their nano-scaled size and…”
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Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization by Lim, Chol Seung, Porter, Dale W, Orandle, Marlene S, Green, Brett J, Barnes, Mark A, Croston, Tara L, Wolfarth, Michael G, Battelli, Lori A, Andrew, Michael E, Beezhold, Donald H, Siegel, Paul D, Ma, Qiang

“…Pulmonary exposure to certain engineered nanomaterials (ENMs) causes chronic lesions like fibrosis and cancer in animal models as a result of unresolved…”
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mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice by Dymacek, Julian, Snyder-Talkington, Brandi N, Porter, Dale W, Mercer, Robert R, Wolfarth, Michael G, Castranova, Vincent, Qian, Yong, Guo, Nancy L

“…Multi-walled carbon nanotubes (MWCNTs) are known for their transient inflammatory and progressive fibrotic pulmonary effects; however, the mechanisms…”
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Multi-Walled Carbon Nanotube-Induced Gene Expression Biomarkers for Medical and Occupational Surveillance by Snyder-Talkington, Brandi N, Dong, Chunlin, Singh, Salvi, Raese, Rebecca, Qian, Yong, Porter, Dale W, Wolfarth, Michael G, Guo, Nancy L

“…As the demand for multi-walled carbon nanotube (MWCNT) incorporation into industrial and biomedical applications increases, so does the potential for…”
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Multiwalled Carbon Nanotube-Induced Gene Signatures in the Mouse Lung: Potential Predictive Value for Human Lung Cancer Risk and Prognosis by Guo, Nancy L., Wan, Ying-Wooi, Denvir, James, Porter, Dale W., Pacurari, Maricica, Wolfarth, Michael G., Castranova, Vincent, Qian, Yong

“…Concerns over the potential for multiwalled carbon nanotubes (MWCNT) to induce lung carcinogenesis have emerged. This study sought to (1) identify gene…”
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Differential mouse pulmonary dose and time course responses to titanium dioxide nanospheres and nanobelts by Porter, Dale W, Wu, Nianqiang, Hubbs, Ann F, Mercer, Robert R, Funk, Kathleen, Meng, Fanke, Li, Jiangtian, Wolfarth, Michael G, Battelli, Lori, Friend, Sherri, Andrew, Michael, Hamilton, Jr, Raymond, Sriram, Krishnan, Yang, Feng, Castranova, Vincent, Holian, Andrij

“…Three anatase titanium dioxide (TiO(2)) nanoparticles (NPs) were prepared; nanospheres (NSs), short nanobelts (NB1), and long nanobelts (NB2). These NPs were…”
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Multiwalled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and genomic changes following aspiration exposure in mice: A 1-year postexposure study by Snyder-Talkington, Brandi N., Dong, Chunlin, Porter, Dale W., Ducatman, Barbara, Wolfarth, Michael G., Andrew, Michael, Battelli, Lori, Raese, Rebecca, Castranova, Vincent, Guo, Nancy L., Qian, Yong

“…Pulmonary exposure to multiwalled carbon nanotubes (MWCNT) induces an inflammatory and rapid fibrotic response, although the long-term signaling mechanisms are…”
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Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes by Porter, Dale W, Hubbs, Ann F, Mercer, Robert R, Wu, Nianqiang, Wolfarth, Michael G, Sriram, Krishnan, Leonard, Stephen, Battelli, Lori, Schwegler-Berry, Diane, Friend, Sherry, Andrew, Michael, Chen, Bean T, Tsuruoka, Shuji, Endo, Morinobu, Castranova, Vincent

“…Abstract Carbon nanotubes (CNT) come in a variety of types, but one of the most common forms is multi-walled carbon nanotubes (MWCNT). MWCNT have potential…”
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Adjuvant effect of zymosan after pulmonary treatment in a mouse ovalbumin allergy model by Young, Shih-Houng, Wolfarth, Michael G., Roberts, Jenny R., Kashon, Michael L., Antonini, James M.

“…ABSTRACTAn association has been observed between indoor mold contamination and lung allergy and asthma. This relationship is not fully understood. 1→3-β-Glucan…”
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Influence of Impurities from Manufacturing Process on the Toxicity Profile of Boron Nitride Nanotubes by Kodali, Vamsi, Kim, Keun Su, Roberts, Jenny R., Bowers, Lauren, Wolfarth, Michael G., Hubczak, John, Xin, Xing, Eye, Tracy, Friend, Sherri, Stefaniak, Aleksandr B., Leonard, Stephen S., Jakubinek, Michael, Erdely, Aaron

“…The toxicity of boron nitride nanotubes (BNNTs) has been the subject of conflicting reports, likely due to differences in the residuals and impurities that can…”
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Acute pulmonary dose-responses to inhaled multi-walled carbon nanotubes by Porter, Dale W., Hubbs, Ann F., Chen, Bean T., McKinney, Walter, Mercer, Robert R., Wolfarth, Michael G., Battelli, Lori, Wu, Nianqiang, Sriram, Krishnan, Leonard, Stephen, Andrew, Michael, Willard, Patsy, Tsuruoka, Shuji, Endo, Morinobu, Tsukada, Takayuki, Munekane, Fuminori, Frazer, David G., Castranova, Vincent

“…Abstract This study investigated the in vivo pulmonary toxicity of inhaled multi-walled carbon nanotubes (MWCNT). Mice-inhaled aerosolized MWCNT (10 mg/m3, 5…”
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Potent lung tumor promotion by inhaled MWCNT by Porter, Dale W, Orandle, Marlene S, Hubbs, Ann, Staska, Lauren M, Lowry, David, Kashon, Michael, Wolfarth, Michael G, McKinney, Walter, Sargent, Linda M

“…In the lung, carcinogenesis is a multi-stage process that includes initiation by a genotoxic agent, promotion that expands the population of cells with damaged…”
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Multi-walled carbon nanotube-induced gene expression in vitro : Concordance with in vivo studies by Snyder-Talkington, Brandi N, Dong, Chunlin, Zhao, Xiangyi, Dymacek, Julian, Porter, Dale W, Wolfarth, Michael G, Castranova, Vincent, Qian, Yong, Guo, Nancy L

“…Abstract There is a current interest in reducing the in vivo toxicity testing of nanomaterials in animals by increasing toxicity testing using in vitro…”
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Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family by Roberts, Jenny R, Mercer, Robert R, Stefaniak, Aleksandr B, Seehra, Mohindar S, Geddam, Usha K, Chaudhuri, Ishrat S, Kyrlidis, Angelos, Kodali, Vamsi K, Sager, Tina, Kenyon, Allison, Bilgesu, Suzan A, Eye, Tracy, Scabilloni, James F, Leonard, Stephen S, Fix, Natalie R, Schwegler-Berry, Diane, Farris, Breanne Y, Wolfarth, Michael G, Porter, Dale W, Castranova, Vincent, Erdely, Aaron

“…Graphene, a monolayer of carbon, is an engineered nanomaterial (ENM) with physical and chemical properties that may offer application advantages over other…”
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System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses by Snyder-Talkington, Brandi N., Dymacek, Julian, Porter, Dale W., Wolfarth, Michael G., Mercer, Robert R., Pacurari, Maricica, Denvir, James, Castranova, Vincent, Qian, Yong, Guo, Nancy L.

“…The fibrous shape and biopersistence of multi-walled carbon nanotubes (MWCNT) have raised concern over their potential toxicity after pulmonary exposure. As in…”
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Acute in vitro and in vivo toxicity of a commercial grade boron nitride nanotube mixture by Kodali, Vamsi K., Roberts, Jenny R., Shoeb, Mohammad, Wolfarth, Michael G., Bishop, Lindsey, Eye, Tracy, Barger, Mark, Roach, Katherine A., Friend, Sherri, Schwegler-Berry, Diane, Chen, Bean T., Stefaniak, Aleksandr, Jordan, Kevin C., Whitney, Roy R., Porter, Dale W., Erdely, Aaron D.

“…Boron nitride nanotubes (BNNTs) are an emerging engineered nanomaterial attracting significant attention due to superior electrical, chemical and thermal…”
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Mouse pulmonary dose- and time course-responses induced by exposure to nitrogen-doped multi-walled carbon nanotubes by Porter, Dale W., Orandle, Marlene, Zheng, Peng, Wu, Nianqiang, Hamilton, Raymond F., Holian, Andrij, Chen, Bean T., Andrew, Michael, Wolfarth, Michael G., Battelli, Lori, Tsuruoka, Shuji, Terrones, Mauricio, Castranova, Vince

“…Objective: In this study, we compared in vitro and in vivo bioactivity of nitrogen-doped multi-walled carbon nanotubes (NDMWCNT) to MWCNT to test the…”
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Similar and Differential Canonical Pathways and Biological Processes Associated With Multiwalled Carbon Nanotube and Asbestos-Induced Pulmonary Fibrosis: A 1-Year Postexposure Study by Dymacek, Julian M., Snyder-Talkington, Brandi N., Raese, Rebecca, Dong, Chunlin, Singh, Salvi, Porter, Dale W., Ducatman, Barbara, Wolfarth, Michael G., Andrew, Michal E., Battelli, Lori, Castranova, Vincent, Qian, Yong, Guo, Nancy L.

“…Respiratory exposure to multiwalled carbon nanotubes (MWCNT) or asbestos results in fibrosis; however, the mechanisms to reach this end point may be different…”
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Pulmonary Cerium Dioxide Nanoparticle Exposure Differentially Impairs Coronary and Mesenteric Arteriolar Reactivity by Minarchick, Valerie C., Stapleton, Phoebe A., Porter, Dale W., Wolfarth, Michael G., Çiftyürek, Engin, Barger, Mark, Sabolsky, Edward M., Nurkiewicz, Timothy R.

“…Cerium dioxide nanoparticles (CeO 2 NPs) are an engineered nanomaterial (ENM) that possesses unique catalytic, oxidative, and reductive properties. Currently,…”
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