Search Results - "Wolf‐Watz, Hans"

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells by Cornelis, Guy R., Wolf‐Watz, Hans

“…The Yop virulon enables Yersinia spp. (Y. pestis, Y. pseudotuberculosis and Y. enterocolitica) to survive and multiply in the lymphoid tissues of their host…”
Get full text

GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure by Von Pawel‐Rammingen, Ulrich, Telepnev, Maxim V., Schmidt, Gudula, Aktories, Klaus, Wolf‐Watz, Hans, Rosqvist, Roland

“…The YopE cytotoxin of Yersinia pseudotuberculosis is an essential virulence determinant that is injected into the eukaryotic target cell via a plasmid‐encoded…”
Get full text

The V‐antigen of Yersinia is surface exposed before target cell contact and involved in virulence protein translocation by Pettersson, Jonas, Holmström, Anna, Hill, Jim, Leary, Sophie, Frithz‐Lindsten, Elisabet, Von Euler‐Matell, Anne, Carlsson, Eva, Titball, Richard, Forsberg, Åke, Wolf‐Watz, Hans

“…Type III‐mediated translocation of Yop effectors is an essential virulence mechanism of pathogenic YersiniaLcrV is the only protein secreted by the type III…”
Get full text

LcrV is a channel size‐determining component of the Yop effector translocon of Yersinia by Holmström, Anna, Olsson, Jan, Cherepanov, Peter, Maier, Elke, Nordfelth, Roland, Pettersson, Jonas, Benz, Roland, Wolf‐Watz, Hans, Forsberg, Åke

“…Delivery of Yop effector proteins by pathogenic Yersinia across the eukaryotic cell membrane requires LcrV, YopB and YopD. These proteins were also required…”
Get full text

Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence by Böhme, Katja, Steinmann, Rebekka, Kortmann, Jens, Seekircher, Stephanie, Heroven, Ann Kathrin, Berger, Evelin, Pisano, Fabio, Thiermann, Tanja, Wolf-Watz, Hans, Narberhaus, Franz, Dersch, Petra

“…Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including the yop effector and the ysc type III secretion genes, is…”
Get full text

A bacterial secreted translocator hijacks riboregulators to control type III secretion in response to host cell contact by Kusmierek, Maria, Hoßmann, Jörn, Witte, Rebekka, Opitz, Wiebke, Vollmer, Ines, Volk, Marcel, Heroven, Ann Kathrin, Wolf-Watz, Hans, Dersch, Petra

“…Numerous Gram-negative pathogens use a Type III Secretion System (T3SS) to promote virulence by injecting effector proteins into targeted host cells, which…”
Get full text

Translocation of surface-localized effectors in type III secretion by Akopyan, Karen, Edgren, Tomas, Wang-Edgren, Helen, Rosqvist, Roland, Fahlgren, Anna, Wolf-Watz, Hans, Fallman, Maria

“…Pathogenic Yersinia species suppress the host immune response by using a plasmid-encoded type III secretion system (T3SS) to translocate virulence proteins…”
Get full text

Characterization of the Ruler Protein Interaction Interface on the Substrate Specificity Switch Protein in the Yersinia Type III Secretion System by Ho, Oanh, Rogne, Per, Edgren, Tomas, Wolf-Watz, Hans, Login, Frédéric H, Wolf-Watz, Magnus

“…Many pathogenic Gram-negative bacteria use the type III secretion system (T3SS) to deliver effector proteins into eukaryotic host cells. In , the switch to…”
Get full text

Chemotactic motility is required for invasion of the host by the fish pathogen Vibrio anguillarum by O'Toole, R, Milton, D L, Wolf-Watz, H

“…The role of the flagellum and motility in the virulence of the marine fish pathogen Vibrio anguillarum was examined. Non-motile mutants were generated by…”
Get more information

Type III secretion in Yersinia: injectisome or not? by Edgren, Tomas, Forsberg, Ake, Rosqvist, Roland, Wolf-Watz, Hans

“…Recent attempts to visualize T3SS substrates during infection using immunogold labeling and transmission electron microscopic analysis revealed that the…”
Get full text

Yersinia pseudotuberculosis Effector YopJ Subverts the Nod2/RICK/TAK1 Pathway and Activates Caspase-1 to Induce Intestinal Barrier Dysfunction by Meinzer, Ulrich, Barreau, Frederick, Esmiol-Welterlin, Sophie, Jung, Camille, Villard, Claude, Léger, Thibaut, Ben-Mkaddem, Sanah, Berrebi, Dominique, Dussaillant, Monique, Alnabhani, Ziad, Roy, Maryline, Bonacorsi, Stéphane, Wolf-Watz, Hans, Perroy, Julie, Ollendorff, Vincent, Hugot, Jean-Pierre

“…Yersinia pseudotuberculosis is an enteropathogenic bacteria that disrupts the intestinal barrier and invades its host through gut-associated lymphoid tissue…”
Get full text

A Small-Molecule Inhibitor of Type III Secretion Inhibits Different Stages of the Infectious Cycle of Chlamydia trachomatis by Muschiol, Sandra, Bailey, Leslie, Gylfe, Åsa, Sundin, Charlotta, Hultenby, Kjell, Bergström, Sven, Elofsson, Mikael, Wolf-Watz, Hans, Normark, Staffan, Henriques-Normark, Birgitta

“…The intracellular pathogen Chlamydia trachomatis possesses a type III secretion (TTS) system believed to deliver a series of effector proteins into the…”
Get full text

Inhibition of Type III Secretion in Salmonella enterica Serovar Typhimurium by Small-Molecule Inhibitors by HUDSON, Debra L, LAYTON, Abigail N, FIELD, Terry R, BOWEN, Alison J, WOLF-WATZ, Hans, ELOFSSON, Mikael, STEVENS, Mark P, GALYOV, Edouard E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Salicylidene Acylhydrazides That Affect Type III Protein Secretion in Salmonella enterica Serovar Typhimurium by NEGREA, Aurel, BJUR, Eva, YGBERG, Sofia Eriksson, ELOFSSON, Mikael, WOLF-WATZ, Hans, RHEN, Mikael

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Identification of a Molecular Target for the Yersinia Protein Kinase A by Navarro, Lorena, Koller, Antonius, Nordfelth, Roland, Wolf-Watz, Hans, Taylor, Susan, Dixon, Jack E.

“…Pathogenic bacteria of the genus Yersinia employ a type III secretion system to inject bacterial effector proteins directly into the host cytosol. One of these…”
Get full text

Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity by Engström, Patrik, Nguyen, Bidong D, Normark, Johan, Nilsson, Ingela, Bastidas, Robert J, Gylfe, Asa, Elofsson, Mikael, Fields, Kenneth A, Valdivia, Raphael H, Wolf-Watz, Hans, Bergström, Sven

“…OA  Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Metabolic profiling for detection of Staphylococcus aureus infection and antibiotic resistance by Antti, Henrik, Fahlgren, Anna, Näsström, Elin, Kouremenos, Konstantinos, Sundén-Cullberg, Jonas, Guo, Yongzhi, Moritz, Thomas, Wolf-Watz, Hans, Johansson, Anders, Fallman, Maria

“…Due to slow diagnostics, physicians must optimize antibiotic therapies based on clinical evaluation of patients without specific information on causative…”
Get full text

The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function by Thorslund, Sara E, Edgren, Tomas, Pettersson, Jonas, Nordfelth, Roland, Sellin, Mikael E, Ivanova, Ekaterina, Francis, Matthew S, Isaksson, Elin L, Wolf-Watz, Hans, Fällman, Maria

“…Many gram-negative bacteria use type III secretion systems to translocate effector proteins into host cells. These effectors interfere with cellular functions…”
Get full text

Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle by Bailey, Leslie, Gylfe, Åsa, Sundin, Charlotta, Muschiol, Sandra, Elofsson, Mikael, Nordström, Peter, Henriques-Normark, Birgitta, Lugert, Raimond, Waldenström, Anders, Wolf-Watz, Hans, Bergström, Sven

“…Intracellular parasitism by Chlamydiales is a complex process involving transmission of metabolically inactive particles that differentiate, replicate, and…”
Get full text

Type III secretion translocon assemblies that attenuate Yersinia virulence by Costa, Tiago R. D., Amer, Ayad A. A., Farag, Salah I., Wolf‐Watz, Hans, Fällman, Maria, Fahlgren, Anna, Edgren, Tomas, Francis, Matthew S.

“…Summary Type III secretion enables bacteria to intoxicate eukaryotic cells with anti‐host effectors. A class of secreted cargo are the two hydrophobic…”
Get full text