Search Results - "Wolf, Eric J"
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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1
Published in PloS one (08-11-2023)“…The chemical modification of RNA bases represents a ubiquitous activity that spans all domains of life. Pseudouridylation is the most common RNA modification…”
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2
The extensive m5C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily
Published in Nature communications (23-08-2024)“…RNAs are often modified to invoke new activities. While many modifications are limited in frequency, restricted to non-coding RNAs, or present only in select…”
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Journal Article -
3
MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development
Published in Cell reports (Cambridge) (26-05-2020)“…The mammalian mRNA nuclear export process is thought to terminate at the cytoplasmic face of the nuclear pore complex through ribonucleoprotein remodeling. We…”
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4
Incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated with nepafenac
Published in Journal of cataract and refractive surgery (01-09-2007)“…Purpose To compare the incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated postoperatively…”
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5
Management of ocular inflammation and pain following cataract surgery: focus on bromfenac ophthalmic solution
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2009)“…Recently, several new ophthalmic NSAID products have been introduced for commercial use in the United States. The purpose of this review is to briefly overview…”
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6
Human RNase 4 improves mRNA sequence characterization by LC–MS/MS
Published in Nucleic acids research (14-10-2022)“…With the rapid growth of synthetic messenger RNA (mRNA)-based therapeutics and vaccines, the development of analytical tools for characterization of long,…”
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Journal Article -
7
TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes
Published in Nucleic acids research (18-11-2020)“…Abstract While splicing has been shown to enhance nuclear export, it has remained unclear whether mRNAs generated from intronless genes use specific machinery…”
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8
Enzymatic characterization of mRNA cap adenosine-N6 methyltransferase PCIF1 activity on uncapped RNAs
Published in The Journal of biological chemistry (01-04-2022)“…The phosphorylated RNA polymerase II CTD interacting factor 1 (PCIF1) is a methyltransferase that adds a methyl group to the N6-position of 2′O-methyladenosine…”
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9
A novel N 4, N 4-dimethylcytidine in the archaeal ribosome enhances hyperthermophily
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2024)“…Ribosome structure and activity are challenged at high temperatures, often demanding modifications to ribosomal RNAs (rRNAs) to retain translation fidelity…”
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10
ZFC3H1 and U1-70K promote the nuclear retention of mRNAs with 5' splice site motifs within nuclear speckles
Published in RNA (Cambridge) (01-06-2022)“…Quality control of mRNA represents an important regulatory mechanism for gene expression in eukaryotes. One component of this quality control is the nuclear…”
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11
Enhanced expression and purification of nucleotide-specific ribonucleases MC1 and Cusativin
Published in Protein expression and purification (01-02-2022)“…Combinations of ribonucleases (RNases) are commonly used to digest RNA into oligoribonucleotide fragments prior to liquid chromatography-mass spectrometry…”
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12
Selective Characterization of mRNA 5′ End-Capping by DNA Probe-Directed Enrichment with Site-Specific Endoribonucleases
Published in ACS pharmacology & translational science (10-11-2023)“…The N7-methyl guanosine cap structure is an essential 5′ end modification of eukaryotic mRNA. It plays a critical role in many aspects of the life cycle of…”
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13
Reactive lymphoid hyperplasia of the nasolacrimal duct presenting as bloody epiphora
Published in Ophthalmic plastic and reconstructive surgery (01-05-2007)“…A 90-year-old man reported a 1-year history of tearing and irritation in the left eye. Ophthalmic examination was significant for bloody mucopurulent material…”
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Journal Article -
14
A novel N4,N4-dimethylcytidine in the archaeal ribosome enhances hyperthermophily
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2024)“…Ribosome structure and activity are challenged at high temperatures, often demanding modifications to ribosomal RNAs (rRNAs) to retain translation fidelity…”
Get full text
Journal Article -
15
The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1
Published in PloS one (01-01-2023)Get full text
Journal Article -
16
The extensive m 5 C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily
Published in Nature communications (23-08-2024)“…RNAs are often modified to invoke new activities. While many modifications are limited in frequency, restricted to non-coding RNAs, or present only in select…”
Get full text
Journal Article -
17
MKRN2 Interacts with GLE1 and Negatively Regulates mRNA Nuclear Export and Retinal Development
Published 01-01-2019“…Canonical mammalian mRNA export is terminated at the cytoplasmic face of the nuclear pore complex. A key factor implicated in mRNA export termination is GLE1,…”
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Dissertation