Search Results - "Wolf, Christine"
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1
Algorithmic management in a work context
Published in Big data & society (01-07-2021)“…The rapid development of machine-learning algorithms, which underpin contemporary artificial intelligence systems, has created new opportunities for the…”
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Artificial intelligence and the world of work, a co‐constitutive relationship
Published in Journal of the Association for Information Science and Technology (01-01-2021)“…The use of intelligent machines—digital technologies that feature data‐driven forms of customization, learning, and autonomous action—is rapidly growing and…”
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Familial chilblain lupus due to a gain-of-function mutation in STING
Published in Annals of the rheumatic diseases (01-02-2017)“…Familial chilblain lupus is a monogenic form of cutaneous lupus erythematosus caused by loss-of-function mutations in the nucleases TREX1 or SAMHD1. In a…”
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4
Action needed for the EU Common Agricultural Policy to address sustainability challenges
Published in People and nature (Hoboken, N.J.) (01-06-2020)“…Making agriculture sustainable is a global challenge. In the European Union (EU), the Common Agricultural Policy (CAP) is failing with respect to biodiversity,…”
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Temporal Improvement of a COVID-19-Positive Crohn's Disease Patient Treated With Bismuth Subsalicylate
Published in The American journal of gastroenterology (01-08-2020)Get full text
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RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA
Published in Nature communications (27-05-2016)“…Immune recognition of cytosolic DNA represents a central antiviral defence mechanism. Within the host, short single-stranded DNA (ssDNA) continuously arises…”
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Struggling for space and finding my place: An interactionist perspective on everyday use of biomedical information
Published in Journal of the Association for Information Science and Technology (01-02-2015)“…Information use intrigues information behavior researchers, though many have struggled with how to conceptualize and study this phenomenon. Some work suggests…”
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From Biology to Therapy: The CLL Success Story
Published in HemaSphere (01-04-2019)“…Chemoimmunotherapy has been the standard of care for patients with chronic lymphocytic leukemia (CLL) over the last decade. Advances in monoclonal antibody…”
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Making Sense of Enterprise Apps in Everyday Work Practices
Published in Computer supported cooperative work (01-04-2020)“…This paper draws attention to the growing adoption of web and mobile apps in the enterprise, typically supported by digital storage in the cloud. While these…”
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Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
Published in Nature immunology (01-08-2010)“…How Roquin controls expression of the inducible costimulator ICOS remains unclear. Heissmeyer and co-workers now show that Roquin binds to the 3' untranslated…”
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Case Report: Response of cutaneous lupus lesions in SLE to interferon receptor blockade parallels reduction of interferon score in blood
Published in Frontiers in immunology (21-09-2023)“…Cutaneous lupus erythematosus (CLE), the main manifestation of systemic lupus erythematosus (SLE), is driven by type I interferons (IFNs) and often only…”
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Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3
Published in The Journal of experimental medicine (01-07-2019)“…The RNase Regnase-1 is a master RNA regulator in macrophages and T cells that degrades cellular and viral RNA upon NF-κB signaling. The roles of its family…”
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Generation of induced pluripotent stem cell lines from three patients with Aicardi-Goutières syndrome type 5 due to biallelic SAMDH1 mutations
Published in Stem cell research (01-10-2022)“…Mutations in SAMHD1, encoding SAM and HD domain-containing protein 1, cause Aicardi-Goutières syndrome (AGS) 5, an infancy-onset autoinflammatory disease…”
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Generation of induced pluripotent stem cell lines from two patients with Aicardi-Goutières syndrome type 1 due to biallelic TREX1 mutations
Published in Stem cell research (01-10-2022)“…Mutations in TREX1, encoding three prime repair exonuclease 1, cause Aicardi-Goutières syndrome (AGS) 1, an autoinflammatory disease characterized by…”
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Monogenic lupus – from gene to targeted therapy
Published in Molecular and cellular pediatrics (12-09-2024)“…Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by loss of tolerance to nuclear antigens. The formation of autoantibodies…”
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A rare manifestation of STING-associated vasculopathy with onset in infancy: a case report
Published in Pediatric rheumatology online journal (04-01-2024)“…STING-associated vasculopathy with onset in infancy (SAVI) is a rare type I interferonopathy caused by heterozygous variants in the STING gene. In SAVI, STING…”
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Rapid and sustained response to JAK inhibition in a child with severe MDA5 + juvenile dermatomyositis
Published in Pediatric rheumatology online journal (19-09-2023)“…Abstract Background Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood. Amyopathic or hypomyopathic courses have…”
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High-Flow Nasal Cannula on the General Ward for Patients With COVID-19 Enhances ICU and Rapid Response Team Resource Allocation
Published in Respiratory care (01-12-2022)Get full text
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Precision treatment of Singleton Merten syndrome with ruxolitinib: a case report
Published in Pediatric rheumatology online journal (11-04-2022)“…Singleton-Merten syndrome 1 (SGMRT1) is a rare type I interferonopathy caused by heterozygous mutations in the IFIH1 gene. IFIH1 encodes the pattern…”
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Water Quality Is a Poor Predictor of Recreational Hotspots in England
Published in PloS one (22-11-2016)“…Maintaining and improving water quality is key to the protection and restoration of aquatic ecosystems, which provide important benefits to society. In Europe,…”
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