Search Results - "Wolf, Alexander"

Integrated Optical Deformation Measurement with TIR Prism Rods by Wolf, Alexander

“…In this paper, a novel optical measurement principle for deformation, especially torsion, is presented. A laser beam is guided via total internal reflection…”
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Generalizing RNA velocity to transient cell states through dynamical modeling by Bergen, Volker, Lange, Marius, Peidli, Stefan, Wolf, F. Alexander, Theis, Fabian J.

“…RNA velocity has opened up new ways of studying cellular differentiation in single-cell RNA-sequencing data. It describes the rate of gene expression change…”
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Blue light-induced oxidative stress in live skin by Nakashima, Yuya, Ohta, Shigeo, Wolf, Alexander M.

“…Skin damage from exposure to sunlight induces aging-like changes in appearance and is attributed to the ultraviolet (UV) component of light. Photosensitized…”
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Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics by Plass, Mireya, Solana, Jordi, Wolf, F Alexander, Ayoub, Salah, Misios, Aristotelis, Glažar, Petar, Obermayer, Benedikt, Theis, Fabian J, Kocks, Christine, Rajewsky, Nikolaus

“…Flatworms of the species are immortal-adult animals contain a large pool of pluripotent stem cells that continuously differentiate into all adult cell types…”
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SCANPY: large-scale single-cell gene expression data analysis by Wolf, F Alexander, Angerer, Philipp, Theis, Fabian J

“…SCANPY is a scalable toolkit for analyzing single-cell gene expression data. It includes methods for preprocessing, visualization, clustering, pseudotime and…”
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Rodent diet aids and the fallacy of caloric restriction by Wolf, Alexander M.

“…•Caloric restriction extends life span mostly by reducing excess mortality due to obesity.•Most pharmacologic interventions to slow aging, including…”
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The tumor suppression theory of aging by Wolf, Alexander M.

“…•Somatic mutations accumulating during cell division are the cause of aging and cancer.•Nutrient signaling paces aging through its effect on cell proliferation…”
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A test metric for assessing single-cell RNA-seq batch correction by Büttner, Maren, Miao, Zhichao, Wolf, F. Alexander, Teichmann, Sarah A., Theis, Fabian J.

“…Single-cell transcriptomics is a versatile tool for exploring heterogeneous cell populations, but as with all genomics experiments, batch effects can hamper…”
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Conditional out-of-distribution generation for unpaired data using transfer VAE by Lotfollahi, Mohammad, Naghipourfar, Mohsen, Theis, Fabian J, Wolf, F Alexander

“…Abstract Motivation While generative models have shown great success in sampling high-dimensional samples conditional on low-dimensional descriptors (stroke…”
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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells by Wolf, F Alexander, Hamey, Fiona K, Plass, Mireya, Solana, Jordi, Dahlin, Joakim S, Göttgens, Berthold, Rajewsky, Nikolaus, Simon, Lukas, Theis, Fabian J

“…Single-cell RNA-seq quantifies biological heterogeneity across both discrete cell types and continuous cell transitions. Partition-based graph abstraction…”
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Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time- and dose-dependent manner in rats by Ulbrich, Felix, Schallner, Nils, Coburn, Mark, Loop, Torsten, Lagrèze, Wolf Alexander, Biermann, Julia, Goebel, Ulrich

“…Retinal ischemia and reperfusion injuries (IRI) permanently affect neuronal tissue and function by apoptosis and inflammation due to the limited regenerative…”
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Harmonizing the Different Perspectives on Growth Impairment in Pediatric CKD by Zhou, Melissa S, Wolf, Alexander J, Sutha, Ken

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Neuroprotection and neuroregeneration of retinal ganglion cells after intravitreal carbon monoxide release by Stifter, Julia, Ulbrich, Felix, Goebel, Ulrich, Böhringer, Daniel, Lagrèze, Wolf Alexander, Biermann, Julia

“…Retinal ischemia induces apoptosis leading to neurodegeneration and vision impairment. Carbon monoxide (CO) in gaseous form showed cell-protective and…”
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Reconstructing cell cycle and disease progression using deep learning by Eulenberg, Philipp, Köhler, Niklas, Blasi, Thomas, Filby, Andrew, Carpenter, Anne E., Rees, Paul, Theis, Fabian J., Wolf, F. Alexander

“…We show that deep convolutional neural networks combined with nonlinear dimension reduction enable reconstructing biological processes based on raw image data…”
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How to discretize a quantum bath for real-time evolution by de Vega, Inés, Schollwöck, Ulrich, Wolf, F. Alexander

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Transgenic type2 diabetes mouse models for in vivo redox measurement of hepatic mitochondrial oxidative stress by Kamimura, Naomi, Wolf, Alexander M., Yokota, Takashi, Nito, Chikako, Takahashi, Hiroshi, Ohta, Shigeo

“…Oxidative stress is involved in the progression of diabetes and its associated complications. However, it is unclear whether increased oxidative stress plays a…”
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The Role of Excitation Energy in Photobrightening and Photodegradation of Halide Perovskite Thin Films by Quitsch, Wolf-Alexander, deQuilettes, Dane W, Pfingsten, Oliver, Schmitz, Alexander, Ognjanovic, Stevan, Jariwala, Sarthak, Koch, Susanne, Winterer, Markus, Ginger, David S, Bacher, Gerd

“…We study the impact of excitation energy on the photostability of methylammonium lead triiodide (CH3NH3PbI3 or MAPI) perovskite thin films. Light soaking leads…”
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Protein arginine methylation: a prominent modification and its demethylation by Wesche, Juste, Kühn, Sarah, Kessler, Benedikt M., Salton, Maayan, Wolf, Alexander

“…Arginine methylation of histones is one mechanism of epigenetic regulation in eukaryotic cells. Methylarginines can also be found in non-histone proteins…”
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High-Speed GaN/GaInN Nanowire Array Light-Emitting Diode on Silicon(111) by Koester, Robert, Sager, Daniel, Quitsch, Wolf-Alexander, Pfingsten, Oliver, Poloczek, Artur, Blumenthal, Sarah, Keller, Gregor, Prost, Werner, Bacher, Gerd, Tegude, Franz-Josef

“…The high speed on–off performance of GaN-based light-emitting diodes (LEDs) grown in c-plane direction is limited by long carrier lifetimes caused by…”
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Imaginary-Time Matrix Product State Impurity Solver for Dynamical Mean-Field Theory by Wolf, F. Alexander, Go, Ara, McCulloch, Ian P., Millis, Andrew J., Schollwöck, Ulrich

“…We present a new impurity solver for dynamical mean-field theory based on imaginary-time evolution of matrix product states. This converges the…”
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