Search Results - "Wolde, James"

The ability of remaining glomerular podocytes to adapt to the loss of their neighbours decreases with age by van der Wolde, James, Haruhara, Kotaro, Puelles, Victor G., Nikolic-Paterson, David, Bertram, John F., Cullen-McEwen, Luise A.

“…Progressive podocyte loss is a feature of healthy ageing. While previous studies have reported age-related changes in podocyte number, density and size and…”
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Validation of a Three-Dimensional Method for Counting and Sizing Podocytes in Whole Glomeruli by Puelles, Victor G, van der Wolde, James W, Schulze, Keith E, Short, Kieran M, Wong, Milagros N, Bensley, Jonathan G, Cullen-McEwen, Luise A, Caruana, Georgina, Hokke, Stacey N, Li, Jinhua, Firth, Stephen D, Harper, Ian S, Nikolic-Paterson, David J, Bertram, John F

“…Podocyte depletion is sufficient for the development of numerous glomerular diseases and can be absolute (loss of podocytes) or relative (reduced number of…”
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Maternal hypoxia developmentally programs low podocyte endowment in male, but not female offspring by Gonçalves, Gessica D., Walton, Sarah L., Gazzard, Sarah E., Wolde, James, Mathias, Paulo C. F., Moritz, Karen M., Cullen‐McEwen, Luise A., Bertram, John F.

“…Fetal hypoxia is a common complication of pregnancy. We have previously reported that maternal hypoxia in late gestation in mice gives rise to male offspring…”
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Nephron deficit and low podocyte density increase risk of albuminuria and glomerulosclerosis in a model of diabetes by Gazzard, Sarah E., Wolde, James, Haruhara, Kotaro, Bertram, John F., Cullen‐McEwen, Luise A.

“…Podocytes are terminally differentiated epithelial cells in glomeruli. Podocyte injury and loss are features of many diseases leading to chronic kidney disease…”
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Podocyte endowment and the impact of adult body size on kidney health by Cullen-McEwen, Luise A, van der Wolde, James, Haruhara, Kotaro, Tribolet, Leon, Dowling, John P, Bertram, Michael G, de Matteo, Robert, Haas, Fabian, Czogalla, Jan, Okabayashi, Yusuke, Armitage, James A, Black, M Jane, Hoy, Wendy E, Puelles, Victor G, Bertram, John F

“…Low birth weight is a risk factor for chronic kidney disease, whereas adult podocyte depletion is a key event in the pathogenesis of glomerulosclerosis…”
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mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans by Puelles, Victor G., van der Wolde, James W., Wanner, Nicola, Scheppach, Markus W., Cullen-McEwen, Luise A., Bork, Tillmann, Lindenmeyer, Maja T., Gernhold, Lukas, Wong, Milagros N., Braun, Fabian, Cohen, Clemens D., Kett, Michelle M., Kuppe, Christoph, Kramann, Rafael, Saritas, Turgay, van Roeyen, Claudia R., Moeller, Marcus J., Tribolet, Leon, Rebello, Richard, Sun, Yu B.Y., Li, Jinhua, Müller-Newen, Gerard, Hughson, Michael D., Hoy, Wendy E., Person, Fermin, Wiech, Thorsten, Ricardo, Sharon D., Kerr, Peter G., Denton, Kate M., Furic, Luc, Huber, Tobias B., Nikolic-Paterson, David J., Bertram, John F.

“…The cellular origins of glomerulosclerosis involve activation of parietal epithelial cells (PECs) and progressive podocyte depletion. While mammalian target of…”
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Developmental Programming of Glomerular Podocyte Endowment by Bertram, John, Cullen-McEwen, Luise, Gazzard, Sarah, Bertram, michael, van der Wolde, James, Walton, Sarah, Moritz, Karen, Haruhara, Kotaro, Goncalves, Gessica

“…Abstract only A range of perturbations to the maternal environment result in low nephron endowment in offspring, which is often linked to increased blood…”
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