Search Results - "Wold, M."

Verification of Real-Time WSA-ENLIL+Cone Simulations of CME Arrival-Time at the CCMC from 2010 to 2016 by Wold, Alexandra M., Taktakishvili, Aleksandre, Leila Mays, M., Jian, Lan K., Odstrcil, Dusan, MacNeice, Peter

“…The Wang-Sheeley-Arge (WSA)-ENLIL+Cone model is used extensively in space weather operations world-wide to model coronal mass ejection (CME) propagation. As…”
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Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays by Raghavan, Shreya, Ward, Maria R, Rowley, Katelyn R, Wold, Rachel M, Takayama, Shuichi, Buckanovich, Ronald J, Mehta, Geeta

“…Abstract Background Ovarian cancer grows and metastasizes from multicellular spheroidal aggregates within the ascites fluid. Multicellular tumor spheroids are…”
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STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control by Toth, Karoly, Lee, Sang R, Ying, Baoling, Spencer, Jacqueline F, Tollefson, Ann E, Sagartz, John E, Kong, Il-Keun, Wang, Zhongde, Wold, William S M

“…Human adenoviruses have been studied extensively in cell culture and have been a model for studies in molecular, cellular, and medical biology. However, much…”
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Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters by Ying, Baoling, Tollefson, Ann E, Spencer, Jacqueline F, Balakrishnan, Lata, Dewhurst, Stephen, Capella, Cristina, Buller, R Mark L, Toth, Karoly, Wold, William S M

“…Adenovirus infections of immunocompromised patients can develop into deadly multiorgan or systemic disease. The virus is especially threatening for pediatric…”
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The role of spatial variability in coal seam parameters on gas outburst behaviour during coal mining by Wold, M.B., Connell, L.D., Choi, S.K.

“…Gas outburst is recognized as a potentially fatal hazard to be managed during the mining of gassy coal seams. Gas outbursts in Australian coal mines have been…”
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Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model by Toth, Karoly, Spencer, Jacqueline F, Dhar, Debanjan, Sagartz, John E, Buller, R. Mark L, Painter, George R, Wold, William S.M

“…Adenoviruses (Ads) cause a wide array of end-organ and disseminated diseases in severely immunosuppressed patients. For example, [almost equal to]20% of…”
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Myocardial calcium overload during graded hypothermia and after rewarming in an in vivo rat model by Wold, R. M., Kondratiev, T., Tveita, T.

“…Aim Mechanisms underlying cardiac contractile dysfunction during and after rewarming from hypothermia remain largely unknown. We have previously reported…”
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Effect of Preexisting Immunity on Oncolytic Adenovirus Vector INGN 007 Antitumor Efficacy in Immunocompetent and Immunosuppressed Syrian Hamsters by DHAR, Debanjan, SPENCER, Jacqueline F, TOTH, Karoly, WOLD, William S. M

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Nuclear embedded star clusters in NGC 7582 by Wold, M., Galliano, E.

“…We report on the discovery of several compact regions of mid-infrared emission in the star-forming circumnuclear disc of the starburst/Seyfert 2 galaxy NGC…”
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Generation and characterization of an IL2RG knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients by Li, Rong, Ying, Baoling, Liu, Yanan, Spencer, Jacqueline F, Miao, Jinxin, Tollefson, Ann E, Brien, James D, Wang, Yaohe, Wold, William S M, Wang, Zhongde, Toth, Karoly

“…Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important model…”
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Inhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replication by Tavis, John E, Wang, Hong, Tollefson, Ann E, Ying, Baoling, Korom, Maria, Cheng, Xiaohong, Cao, Feng, Davis, Katie L, Wold, William S M, Morrison, Lynda A

“…Herpesviruses are large double-stranded DNA viruses that cause serious human diseases. Herpesvirus DNA replication depends on multiple processes typically…”
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Phase II study of cabazitaxel with or without abiraterone acetate and prednisone in patients with metastatic castrate resistant prostate cancer after prior docetaxel and abiraterone acetate by Kessler, E.R., Gao, D., Flaig, T.W., Breaker, K., Wold, M., Wacker, M., Lam, E.T.

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Adenovirus Death Protein (ADP) Is Required for Lytic Infection of Human Lymphocytes by Murali, V K, Ornelles, D A, Gooding, L R, Wilms, H T, Huang, W, Tollefson, A E, Wold, W S M, Garnett-Benson, C

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Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model by Tollefson, Ann E., Spencer, Jacqueline F., Ying, Baoling, Buller, R. Mark L., Wold, William S.M., Toth, Karoly

“…•A permissive animal model was used to test the efficacy of three drugs against disseminated human adenovirus infection.•These three drugs are used in the…”
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Adenovirus and Oxaliplatin cooperate as agnostic sensitizers for immunogenic cell death in colorectal carcinoma by Jessup, J. Milburn, Kabbout, Mohamed, Korokhov, Nikolay, Joun, Alex, Tollefson, Ann E., Wold, William S. M., Mattoo, Abid R.

“…Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of…”
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Pre-existing Immunity and Passive Immunity to Adenovirus 5 Prevents Toxicity Caused by an Oncolytic Adenovirus Vector in the Syrian Hamster Model by Dhar, Debanjan, Spencer, Jacqueline F, Toth, Karoly, Wold, William SM

“…We have used Syrian hamsters to examine the role of pre-existing immunity to adenovirus (Ad) 5 in the toxicity of the oncolytic Ad vector INGN 007. Groups of…”
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Identification of a Previously Unrecognized Promoter That Drives Expression of the UXP Transcription Unit in the Human Adenovirus Type 5 Genome by BAOLING YING, TOLLEFSON, Ann E, WOLD, William S. M

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Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters by Dhar, D, Toth, K, Wold, W S M

“…Immune responses against oncolytic adenovirus (Ad) vectors are thought to limit vector anti-tumor efficacy. With Syrian hamsters, which are immunocompetent and…”
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The Virology of Taterapox Virus In Vitro by Parker, Scott, Camilo de Oliveira, Leonardo, Lefkowitz, Elliot J, Hendrickson, Robert Curtis, Bonjardim, Cláudio A, Wold, William S M, Hartzler, Hollyce, Crump, Ryan, Buller, Robert Mark

“…Taterapox virus (TATV) is phylogenetically the closest related virus to variola-the etiological agent of smallpox. Despite the similarity, few studies have…”
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The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors by Young, B A, Spencer, J F, Ying, B, Tollefson, A E, Toth, K, Wold, W S M

“…We have previously reported that intratumoral injection of VRX-007—an Ad5 (a species C adenovirus)-based vector overexpressing adenovirus death protein—can…”
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