Search Results - "Wojciak, J M"

Improved NMR spectra of a protein-DNA complex through rational mutagenesis and the application of a sensitivity optimized isotope-filtered NOESY experiment by Iwahara, J, Wojciak, J M, Clubb, R T

“…The NMR spectra of the complex between the DNA-binding domain of the Dead ringer protein (DRI-DBD, Gly262-Gly398) and its DNA binding site (DRI-DBD:DNA, 26…”
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The Mu repressor-DNA complex contains an immobilized 'wing' within the minor groove by Clubb, Robert T, Wojciak, Jonathan M, Iwahara, Junji

“…We have determined the solution structure of the complex between the 'winged-helix' enhancer binding domain of the Mu repressor protein and its cognate DNA…”
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Finding the function buried in SAND by Clubb, Robert T, Wojciak, Jonathan M

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Arm-Site Binding by λ-Integrase: Solution Structure and Functional Characterization of Its Amino-Terminal Domain by Wojciak, Jonathan M., Sarkar, Dibyendu, Landy, Arthur, Clubb, Robert T.

“…The integrase protein (Int) from bacteriophage λ catalyzes the insertion and excision of the viral genome into and out of Escherichia coli. It is a member of…”
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Identification of the λ Integrase Surface That Interacts with Xis Reveals a Residue That Is Also Critical for Int Dimer Formation by Warren, David, Sam, My D., Manley, Kate, Sarkar, Dibyendu, Lee, Sang Yeol, Abbani, Mohamad, Wojciak, Jonathan M., Clubb, Robert T., Landy, Arthur

“…Lambda integrase (Int) is a heterobivalent DNA-binding protein that together with the accessory DNA-bending proteins IHF, Fis, and Xis, forms the higher-order…”
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Major Groove Recognition by Three-stranded β-Sheets: Affinity Determinants and Conserved Structural Features by Connolly, Kevin M., Ilangovan, Udayar, Wojciak, Jonathan M., Iwahara, Mizuho, Clubb, Robert T.

“…We present the results of a rational mutagenesis and binding-affinity study of the three-stranded β-sheet-DNA interface in the complex formed by the…”
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Resonance assignments of the Tn916 integrase DNA-binding domain and the integrase:DNA complex by Connolly, K M, Wojciak, J M, Clubb, R T

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An Efficient NMR Experiment for Analyzing Sugar-Puckering in Unlabeled DNA: Application to the 26-kDa Dead Ringer–DNA Complex by Iwahara, Junji, Wojciak, Jonathan M., Clubb, Robert T.

“…We present a new NMR experiment for estimating the type and degree of sugar-puckering in high-molecular-weight unlabeled DNA molecules. The experiment consists…”
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NMR Structure and Functional Studies of the Mu Repressor DNA-Binding Domain by Ilangovan, Udayar, Wojciak, Jonathan M, Connolly, Kevin M, Clubb, Robert T

“…The repressor protein of bacteriophage Mu establishes and maintains lysogeny by shutting down transposition functions needed for phage DNA replication. It…”
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NMR structure of the Tn916 integrase-DNA complex by Wojciak, J M, Connolly, K M, Clubb, R T

“…The integrase protein catalyzes the excision and integration of the Tn916 conjugative transposon, a promiscuous genetic element that spreads antibiotic…”
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Site-specific DNA binding using a variation of the double stranded RNA binding motif by Clubb, Robert T, Connolly, Kevin M, Wojciak, Jonathan M

“…The integrase family of site-specific recombinases catalyze a diverse array of DNA rearrangements in archaebacteria, eubacteria and yeast. The solution…”
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CBP/p300 TAZ1 Domain Forms a Structured Scaffold for Ligand Binding by De Guzman, Roberto N, Wojciak, Jonathan M, Martinez-Yamout, Maria A, Dyson, H. Jane, Wright, Peter E

“…The transcriptional coactivator protein CBP and its paralog p300 each contain two homologous zinc-containing TAZ domains, which constitute the interaction…”
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Regulation of Directionality in Bacteriophage λ Site-specific Recombination: Structure of the Xis Protein by Sam, My D., Papagiannis, Christie V., Connolly, Kevin M., Corselli, Leah, Iwahara, Junji, Lee, James, Phillips, Martin, Wojciak, Jonathan M., Johnson, Reid C., Clubb, Robert T.

“…Upon induction of a bacteriophage λ lysogen, a site-specific recombination reaction excises the phage genome from the chromosome of its bacterial host. A…”
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Letter to the Editor: Resonance assignments of the Tn916 integrase DNA-binding domain and the integrase:DNA complex by Connolly, Kevin M, Wojciak, Jonathan M, Clubb, Robert T

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