Search Results - "Wohl, G"

Stimulation of functional neuronal regeneration from Müller glia in adult mice by Jorstad, Nikolas L., Wilken, Matthew S., Grimes, William N., Wohl, Stefanie G., VandenBosch, Leah S., Yoshimatsu, Takeshi, Wong, Rachel O., Rieke, Fred, Reh, Thomas A.

“…Inhibition of histone deacetylation allows the transcription factor Ascl1 to bind to key gene loci in Müller glia and drive the functional generation of…”
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Ge-on-Si vertical incidence photodiodes with 39-GHz bandwidth by Jutzi, M., Berroth, M., Wohl, G., Oehme, M., Kasper, E.

“…Vertical-incidence Germanium photodiodes grown on thin strain-relaxed buffers on Silicon substrates are reported. For a mesa-type detector with a diameter of…”
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Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture by Wohl, Stefanie G., Jorstad, Nikolas L., Levine, Edward M., Reh, Thomas A.

“…To better understand the roles of microRNAs in glial function, we used a conditional deletion of Dicer1 (Dicer-CKO MG ) in retinal Müller glia (MG). Dicer1…”
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Primary Cell Cultures to Study the Regeneration Potential of Murine Müller Glia after MicroRNA Treatment by Kang, Seoyoung, Wohl, Stefanie G

“…Müller glia (MG) are the predominant glia in the neural retina and can function as a regenerative source for retinal neurons. In lower vertebrates such as…”
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Developmental changes in the accessible chromatin, transcriptome and Ascl1-binding correlate with the loss in Müller Glial regenerative potential by VandenBosch, Leah S., Wohl, Stefanie G., Wilken, Matthew S., Hooper, Marcus, Finkbeiner, Connor, Cox, Kristen, Chipman, Laura, Reh, Thomas A.

“…Diseases and damage to the retina lead to losses in retinal neurons and eventual visual impairment. Although the mammalian retina has no inherent regenerative…”
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Proliferative response of microglia and macrophages in the adult mouse eye after optic nerve lesion by Wohl, Stefanie G, Schmeer, Christian W, Witte, Otto W, Isenmann, Stefan

“…The purpose of this in vivo study was to evaluate the proliferative response of immunologic cells during the acute phase after optic nerve (ON) lesion in the…”
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A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia-Focus on microRNAs by Kang, Seoyoung, Larbi, Daniel, Andrade, Monica, Reardon, Sara, Reh, Thomas A, Wohl, Stefanie G

“…Müller glia (MG) are the predominant glia in the neural retina and become reactive after injury or in disease. microRNAs (miRNAs) are translational repressors…”
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MicroRNAs miR-25, let-7 and miR-124 regulate the neurogenic potential of Müller glia in mice by Wohl, Stefanie G, Hooper, Marcus J, Reh, Thomas A

“…Müller glial cells (MG) generate retinal progenitor (RPC)-like cells after injury in non-mammalian species, although this does not occur in the mammalian…”
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In situ dividing and phagocytosing retinal microglia express nestin, vimentin, and NG2 in vivo by Wohl, Stefanie G, Schmeer, Christian W, Friese, Thomas, Witte, Otto W, Isenmann, Stefan

“…Following injury, microglia become activated with subsets expressing nestin as well as other neural markers. Moreover, cerebral microglia can give rise to…”
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High-speed germanium photodiodes monolithically integrated on silicon with MBE by Oehme, M., Werner, J., Jutzi, M., Wöhl, G., Kasper, E., Berroth, M.

“…Germanium on silicon pin-photodiodes for vertical light incidence is presented. The monolithically integrated devices are grown on Si with solid source…”
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The microRNA expression profile of mouse Müller glia in vivo and in vitro by Wohl, Stefanie G., Reh, Thomas A.

“…The profile of miRNAs in mature glia is not well characterized, and most studies have been done in cultured glia. In order to identify the miRNAs in adult and…”
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Scientist as detective: Luis Alvarez and the pyramid burial chambers, the JFK assassination, and the end of the dinosaurs by Wohl, C. G

“…Luis Alvarez - 1911-1988 - was one of the most brilliant and productive experimental physicists of the twentieth century. His investigations of three…”
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Neurogenic potential of stem/progenitor-like cells in the adult mammalian eye by Wohl, Stefanie G., Schmeer, Christian W., Isenmann, Stefan

“…The neural retina as part of the brain has received a great deal of attention since quiescent neural stem cells/progenitor cells (NSC/PCs) were discovered in…”
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Antiresorptive therapy conserves some periarticular bone and ligament mechanical properties after anterior cruciate ligament disruption in the rabbit knee by Doschak, M.R, Wohl, G.R, Hanley, D.A, Bray, R.C, Zernicke, R.F

“…The purpose of this study was to assess, in an osteoarthritic (OA) model, whether bisphosphonate (BP) antiresorptive therapy altered periarticular bone and…”
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Frataxin overexpression in Müller cells protects retinal ganglion cells in a mouse model of ischemia/reperfusion injury in vivo by Schultz, Rowena, Krug, Melanie, Precht, Michel, Wohl, Stefanie G., Witte, Otto W., Schmeer, Christian

“…Müller cells are critical for retinal function and neuronal survival but can become detrimental in response to retinal ischemia and increased oxidative stress…”
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Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties by Wohl, G R, Loehrke, L, Watkins, B A, Zernicke, R F

“…Diets with a high saturated fat content can produce deleterious effects on the absorption of dietary calcium and consequently an adverse effect on bone…”
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Cell-replacement therapy and neural repair in the retina by Schmeer, Christian W, Wohl, Stefanie G, Isenmann, Stefan

“…Visual impairment severely affects the quality of life of patients and their families and is also associated with a deep economic impact. The most common…”
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Bone Affinity of a Bisphosphonate-Conjugated Protein in Vivo by Uludag, Hasan, Gao, Tiejun, Wohl, Gregory R., Kantoci, Darko, Zernicke, Ronald F.

“…Growth factors capable of stimulating bone formation are potential therapeutic agents for osteoporosis treatment. It is essential, however, that a targeting…”
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Dietary fish oil supplementation adversely affects cortical bone morphology and biomechanics in growing rabbits by Judex, S, Wohl, G R, Wolff, R B, Leng, W, Gillis, A M, Zernicke, R F

“…Despite substantial evidence that fish oil-derived (n-3) polyunsaturated fatty acids (PUFA) may protect against cardiovascular disease, the effects of…”
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Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo by Wohl, Stefanie G., Schmeer, Christian W., Kretz, Alexandra, Witte, Otto W., Isenmann, Stefan

“…In the naïve adult rodent eye cell proliferation does not occur. The aim of this in vivo study was to evaluate if quiescent putative progenitor-like cells…”
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