Search Results - "Woestenborghs, R J"

Gastrointestinal distribution of the prodrug loperamide oxide and its active drug loperamide in the dog by Van Beijsterveldt, L E, Geerts, R J, Wuyts, K, Woestenborghs, R J, Meuldermans, W E, Heykants, J J

“…Loperamide oxide is a prodrug of the effective antidiarrheal loperamide. Administration of this prodrug improves efficacy and tolerability. For better…”
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Assay methods for sufentanil in plasma : radioimmunoassay versus gas chromatography-mass spectrometry by WOESTENBORGHS, R. J. H, TIMMERMAN, P. M. M. B. L, CORNELISSEN, M.-L. J. E, VAN ROMPAEY, F. A. M. B. S, GEPTS, E, CAMU, F, HEYKANTS, J. J. P, STANSKI, D. R

“…The terminal pharmacokinetic parameters of sufentanil have, until now, been poorly characterized. This is probably because of the poor sensitivity or…”
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Effect of food on the pharmacokinetics of a new hydroxypropyl-beta-cyclodextrin formulation of itraconazole by Van de Velde, V J, Van Peer, A P, Heykants, J J, Woestenborghs, R J, Van Rooy, P, De Beule, K L, Cauwenbergh, G F

“…To compare the pharmacokinetics of a single 100-mg oral dose of itraconazole administered as 10 ml of a 10-mg/ml itraconazole solution in…”
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Assay methods for fentanyl in serum: gas-liquid chromatography versus radioimmunoassay by WOESTENBORGHS, R. J. H, STANSKI, D. R, SCOTT, J. C, HEYKANTS, J. J. P

“…In this study, two independent laboratories assessed the validity of the fentanyl radioimmunoassay (RIA) by measuring a series of spiked control serum samples…”
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Is the metabolism of alfentanil subject to debrisoquine polymorphism? a study using human liver microsomes by LAVRIJSEN, K. L. M, VAN HOUDT, J. M. G, VAN DYCK, D. M. J, HENDRICKX, J. J. J. M, WOESTENBORGHS, R. J. H, LAUERS, W, MEULDERMANS, W. E. G, HEYKANTS, J. J. P

“…The present study was designed to investigate whether the metabolism of the opiate analgesic alfentanil in humans is subject to the debrisoquine…”
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Distribution of oral ketoconazole to vaginal tissue by Heykants, J J, Woestenborghs, R J, Bisschop, M P, Merkus, J M

“…Plasma samples and biopsies of vaginal tissue were obtained from 23 healthy women undergoing operative sterilization, 1 to 6 h after a single oral dose of…”
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Pharmacokinetics of haloperidol decanoate. A 2-year follow-up by Reyntigens, A J, Heykants, J J, Woestenborghs, R J, Gelders, Y G, Aerts, T J

“…Plasma haloperidol levels were assayed in 181 chronic schizophrenic inpatients, who were monthly injected intramuscularly with haloperidol decanoate. Steady…”
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