Search Results - "Wobus, Anna M"

Present state and future perspectives of using pluripotent stem cells in toxicology research by Wobus, Anna M, Löser, Peter

“…The use of novel drugs and chemicals requires reliable data on their potential toxic effects on humans. Current test systems are mainly based on animals or in…”
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Embryonic Stem Cells: Prospects for Developmental Biology and Cell Therapy by Wobus, Anna M, Boheler, Kenneth R

“…In Vitro Differentiation Group, IPK Gatersleben, Gatersleben, Germany; and Laboratory of Cardiovascular Science, National Institute on Aging, National…”
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Expression of Pax4 in Embryonic Stem Cells Promotes Differentiation of Nestin-Positive Progenitor and Insulin-Producing Cells by Blyszczuk, Przemyslaw, Czyz, Jaroslaw, Kania, Gabriela, Wagner, Martin, Roll, Ursula, St-Onge, Luc, Wobus, Anna M.

“…Mouse embryonic stem (ES) cells differentiate into cells of all three primary germ layers including endodermal cells that produce insulin in vitro. We show…”
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Modulation of Calcium-Activated Potassium Channels Induces Cardiogenesis of Pluripotent Stem Cells and Enrichment of Pacemaker-Like Cells by KLEGER, Alexander, SEUFFERLEIN, Thomas, BRUNNER, Cornelia, KATZ, Sarah-Fee, GANESH VARMA PUSAPATI, BULLINGER, Lars, FRANZ, Wolfgang-Michael, KOEHNTOP, Ralf, GIEHL, Klaudia, SPYRANTIS, Andreas, WITTEKINDT, Oliver, QIONG LIN, MALAN, Daniela, ZENKE, Martin, FLEISCHMANN, Bernd K, WARTENBERG, Maria, WOBUS, Anna M, BOECKERS, Tobias M, LIEBAU, Stefan, TISCHENDORF, Michael, STORCH, Alexander, WOLHEIM, Anne, LATZ, Stephan, PROTZE, Stephanie, PORZNER, Marc, PROEPPER, Christian

“…Ion channels are key determinants for the function of excitable cells, but little is known about their role and involvement during cardiac development. Earlier…”
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Differentiation of mouse embryonic stem cells to insulin-producing cells by Wobus, Anna M, Schroeder, Insa S, Rolletschek, Alexandra, Blyszczuk, Przemyslaw, Kania, Gabriela

“…Here, we describe a basic protocol for the in vitro differentiation of mouse embryonic stem (ES) cells into insulin-producing cells. The three-step protocol…”
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Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neural progenitor cells by Nikolova, Teodora, Czyz, Jaroslaw, Rolletschek, Alexandra, Blyszczuk, Przemyslaw, Fuchs, Jörg, Jovtchev, Gabriele, Schuderer, Jůrgen, Kuster, Niels, Wobus, Anna M

“…ABSTRACTMouse embryonic stem (ES) cells were used as an experimental model to study the effects of electromagnetic fields (EMF). ES‐derived nestin‐positive…”
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Pluripotency Associated Genes Are Reactivated by Chromatin‐Modifying Agents in Neurosphere Cells by Ruau, David, Ensenat‐Waser, Roberto, Dinger, Timo C., Vallabhapurapu, Duttu S., Rolletschek, Alexandra, Hacker, Christine, Hieronymus, Thomas, Wobus, Anna M., Müller, Albrecht M., Zenke, Martin

“…Chromatin architecture in stem cells determines the pattern of gene expression and thereby cell identity and fate. The chromatin‐modifying agents trichostatin…”
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Embryonic stem cell differentiation: The role of extracellular factors by Czyz, Jaroslaw, Wobus, Anna M.

“…Embryonic stem (ES) cells have the capacity to self renew and to differentiate into cellular derivatives of the endodermal, ectodermal, and mesodermal…”
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Somatic Stem Cell Marker Prominin‐1/CD133 Is Expressed in Embryonic Stem Cell–Derived Progenitors by Kania, Gabriela, Corbeil, Denis, Fuchs, Joerg, Tarasov, Kirill V., Blyszczuk, Przemyslaw, Huttner, Wieland B., Boheler, Kenneth R., Wobus, Anna M.

“…Prominin‐1/CD133 is a plasma membrane marker found in several types of somatic stem cells, including hematopoietic and neural stem cells. To study its role…”
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Dioxin Affects Glucose Transport via the Arylhydrocarbon Receptor Signal Cascade in Pluripotent Embryonic Carcinoma Cells by Tonack, Sarah, Kind, Karen, Thompson, Jeremy G, Wobus, Anna M, Fischer, Bernd, Santos, Anne Navarrete

“…Intoxication by dioxins such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) leads, among other damages, to early embryo loss, fetal malformations, and…”
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Differentiation plasticity of chondrocytes derived from mouse embryonic stem cells by Hegert, Claudia, Kramer, Jan, Hargus, Gunnar, Müller, Jana, Guan, Kaomei, Wobus, Anna M, Müller, Peter K, Rohwedel, Jürgen

“…Evidence exists that cells of mesenchymal origin show a differentiation plasticity that depends on their differentiation state. We used in vitro…”
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Generation of glycogen- and albumin-producing hepatocyte-like cells from embryonic stem cells by Kania, Gabriela, Blyszczuk, Przemyslaw, Jochheim, Andrea, Ott, Michael, Wobus, Anna M

“…We present a novel two-step protocol for the differentiation of embryonic stem (ES) cells into the hepatic lineage. Differentiated hepatocyte-like cells…”
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Stem cells and pancreatic differentiation in vitro by Blyszczuk, Przemyslaw, Wobus, Anna M.

“…Cell therapy using pancreatic islets would be a promising therapy to treat diabetes. But, because of the limited supply of human donor islets, other cellular…”
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Induction and selection of Sox17-expressing endoderm cells generated from murine embryonic stem cells by Schroeder, Insa S, Sulzbacher, Sabine, Nolden, Tobias, Fuchs, Joerg, Czarnota, Judith, Meisterfeld, Ronny, Himmelbauer, Heinz, Wobus, Anna M

“…Embryonic stem (ES) cells offer a valuable source for generating insulin-producing cells. However, current differentiation protocols often result in…”
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Induction of cellular differentiation by retinoic acid in vitro by Rohwedel, J, Guan, K, Wobus, A M

“…Cellular differentiation by the vitamin A derivative retinoic acid (RA) has been studied with undifferentiated pluripotent embryonic carcinoma (EC) and…”
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High frequency electromagnetic fields (GSM signals) affect gene expression levels in tumor suppressor p53-deficient embryonic stem cells by Czyz, Jaroslaw, Guan, Kaomei, Zeng, Qinghua, Nikolova, Teodora, Meister, Armin, Schönborn, Frank, Schuderer, Jürgen, Kuster, Niels, Wobus, Anna M.

“…Effects of electromagnetic fields (EMF) simulating exposure to the Global System for Mobile Communications (GSM) signals were studied using pluripotent…”
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WNT-conditioned media differentially affect the proliferation and differentiation of cord blood-derived CD133 + cells in vitro by Nikolova, Teodora, Wu, Minyao, Brumbarov, Krassimir, Alt, Rüdiger, Opitz, Heike, Boheler, Kenneth R., Cross, Michael, Wobus, Anna M.

“…Cord blood-derived CD133 + cells have a degree of non-hematopoietic potential and express transcripts of pluripotency markers including Oct-4, Sox-2, Rex-1,…”
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Differential expression of glucose transporter isoforms during embryonic stem cell differentiation by Tonack, Sarah, Rolletschek, Alexandra, Wobus, Anna M., Fischer, Bernd, Santos, Anne Navarrete

“…In mouse blastocysts six facilitative glucose transporter isoforms (GLUT)1–4, 8 and 9 are expressed. We have used the mouse embryonic stem (ES) cell line D3…”
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Human Embryonic Stem Cell Lines and Their Use in International Research by Löser, Peter, Schirm, Jacqueline, Guhr, Anke, Wobus, Anna M., Kurtz, Andreas

“…Research in human pluripotent stem cells, including human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC), is one of the most…”
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Janus face of pluripotent stem cells - Connection between pluripotency and tumourigenicity by Wobus, Anna M

“…Pluripotent stem cells have gained special attraction because of their almost unlimited proliferation and differentiation capacity in vitro. These properties…”
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