Search Results - "Wobus, A M"

Nestin expression--a property of multi-lineage progenitor cells? by Wiese, C, Rolletschek, A, Kania, G, Blyszczuk, P, Tarasov, K V, Tarasova, Y, Wersto, R P, Boheler, K R, Wobus, A M

“…Tissue-specific progenitor cells are characterized by proliferation and differentiation, but, in contrast to embryonic stem (ES) cells, have limited capacities…”
Get full text

Selection of ventricular‐like cardiomyocytes from ES cells in vitro by MÜller, M., Fleischmann, B. K., Selbert, S., Ji, G. J., Endl, E., Middeler, G., MÜller, O. J., Schlenke, P., Frese, S., Wobus, A. M., Hescheler, J., Katus, H. A., Franz, W. M.

“…ABSTRACT Ischemic disorders of the heart can cause an irreversible loss of cardiomyocytes resulting in a substantial decrease of cardiac output. The therapy of…”
Get full text

Potential of embryonic and adult stem cells in vitro by Czyz, Jaroslaw, Wiese, Cornelia, Rolletschek, Alexandra, Blyszczuk, Przemyslaw, Cross, Michael, Wobus, Anna M

“…Recent developments in the field of stem cell research indicate their enormous potential as a source of tissue for regenerative therapies. The success of such…”
Get more information

Muscle Cell Differentiation of Embryonic Stem Cells Reflects Myogenesis in Vivo: Developmentally Regulated Expression of Myogenic Determination Genes and Functional Expression of Ionic Currents by Rohwedel, J., Maltsev, V., Bober, E., Arnold, H.-H., Hescheler, J., Wobus, A.M.

“…The mouse blastocyst-derived embryonic stem cell (ES cell) line BLC6 efficiently differentiates into myosin heavy chain-, desmin- and myogenin-positive…”
Get full text

Embryonic stem cells as an in vitro model for mutagenicity, cytotoxicity and embryotoxicity studies: present state and future prospects by Rohwedel, J, Guan, K, Hegert, C, Wobus, A.M

“…Primary cultures or established cell lines of vertebrates are commonly used to analyse the mutagenic, embryotoxic or teratogenic potential of environmental…”
Get full text

Cardiomyocytes Differentiated In Vitro From Embryonic Stem Cells Developmentally Express Cardiac-Specific Genes and Ionic Currents by Maltsev, Victor A, Wobus, Anna M, Rohwedel, Jürgen, Bader, Michael, Hescheler, Jürgen

“…Cardiomyocytes differentiated in vitro from pluripotent embryonic stem (ES) cells of line D3 via embryo-like aggregates (embryoid bodies) were characterized by…”
Get full text

Embryonic stem cells : a model to study structural and functional properties in cardiomyogenesis by HESCHELER, J, FLEISCHMANN, B. K, LENTINI, S, MALTSEV, V. A, ROHWEDEL, J, WOBUS, A. M, ADDICKS, K

Get full text

Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers by Wobus, A M, Wallukat, G, Hescheler, J

“…A defined cultivation system was developed for the differentiation of pluripotent embryonic stem cells of the mouse into spontaneously beating cardiomyocytes,…”
Get more information

Establishment of beta-Adrenergic Modulation of L-Type Ca2+ Current in the Early Stages of Cardiomyocyte Development by Maltsev, Victor A, Ji, G.J, Wobus, Anna M, Fleischmann, Bernd K, Hescheler, Jurgen

“…beta-Adrenergic modulation of the L-type Ca current (ICaL) was characterized for different developmental stages in murine embryonic stem cell-derived…”
Get full text

Embryonic stem cell differentiation models : cardiogenesis, myogenesis, neurogenesis, epithelial and vascular smooth muscle cell differentiation in vitro by GUAN, K, ROHWEDEL, J, WOBUS, A. M

“…Embryonic stem cells, totipotent cells of the early mouse embryo, were established as permanent cell lines of undifferentiated cells. ES cells provide an…”
Get full text

Embryonic stem cells as a model to study cardiac, skeletal muscle, and vascular smooth muscle cell differentiation by Wobus, A M, Guan, K, Yang, H T, Boheler, K R

Get more information

Lithium influences differentiation and tissue-specific gene expression of mouse embryonic stem (ES) cells in vitro by Schmidt, M M, Guan, K, Wobus, A M

“…The effects of lithium chloride (LiCl) on differentiation of mouse embryonic stem (ES) cells were investigated in order to evaluate the ES cell test (EST) used…”
Get full text

Membrane segregation and downregulation of raft markers during sarcolemmal differentiation in skeletal muscle cells by Draeger, A, Monastyrskaya, K, Burkhard, F.C, Wobus, A.M, Moss, S.E, Babiychuk, E.B

“…Muscle contraction implies flexibility in combination with force resistance and requires a high degree of sarcolemmal organization. Smooth muscle cells…”
Get full text

Generation of pancreatic insulin-producing cells from embryonic stem cells - 'proof of principle', but questions still unanswered by Rolletschek, A, Kania, G, Wobus, A M

Get full text

Design, optimization, realization, and analysis of an in vitro system for the exposure of embryonic stem cells at 1.71 GHz by Schönborn, Frank, Poković, Katja, Wobus, Anna M., Kuster, Niels

“…The aim of this study was to develop an exposure system which enables in vitro experiments to be conducted under variously modulated radiofrequency exposures…”
Get full text

Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neural progenitor cells by Nikolova, Teodora, Czyz, Jaroslaw, Rolletschek, Alexandra, Blyszczuk, Przemyslaw, Fuchs, Jörg, Jovtchev, Gabriele, Schuderer, Jůrgen, Kuster, Niels, Wobus, Anna M

“…ABSTRACTMouse embryonic stem (ES) cells were used as an experimental model to study the effects of electromagnetic fields (EMF). ES‐derived nestin‐positive…”
Get full text

Embryonic stem cell-derived neurogenesis : Retinoic acid induction and lineage selection of neuronal cells by Guan, Kaomei, Chang, Hong, Rolletschek, Alexandra, Wobus, Anna M

“…Embryonic stem (ES) cells are able to differentiate in vitro into endodermal, mesodermal, and ectodermal cell types. However, the spontaneous development of…”
Get full text

Embryonic stem cell differentiation: The role of extracellular factors by Czyz, Jaroslaw, Wobus, Anna M.

“…Embryonic stem (ES) cells have the capacity to self renew and to differentiate into cellular derivatives of the endodermal, ectodermal, and mesodermal…”
Get full text

Human embryonic stem cells within the context of international research activity by Wobus, A M, Löser, P

“…Research involving pluripotent human embryonic stem cells (hESCs) is a rapidly growing field of science. Since hESCs originate from early human embryos,…”
Get full text

Primordial germ cell-derived embryonic germ cells of the mouse—in vitro model for cytotoxicity studies with chemical mutagens by Sehlmeyer, U., Rohwedel, J., Wobus, A.M.

“…Different screening methods to detect the toxic effects of xenobiotics using cells from vertebrates and invertebrates in cytotoxicity and viability assays have…”
Get full text