Search Results - "Wlodarska, I"
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EBV-Positive and EBV-Negative Posttransplant Diffuse Large B Cell Lymphomas Have Distinct Genomic and Transcriptomic Features
Published in American journal of transplantation (01-02-2016)“…The molecular pathogenesis of posttransplant diffuse large B cell lymphoma (PT-DLBCL) is largely unknown. We have recently shown that Epstein-Barr…”
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Gene Expression Profiling Reveals Clear Differences Between EBV‐Positive and EBV‐Negative Posttransplant Lymphoproliferative Disorders
Published in American journal of transplantation (01-05-2013)“…Posttransplant patients are at risk of developing a potentially life‐threatening posttransplantation lymphoproliferative disorder (PTLD), most often of diffuse…”
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Post-transplant molecularly defined Burkitt lymphomas are frequently MYC-negative and characterized by the 11q-gain/loss pattern
Published in Haematologica (Roma) (01-07-2015)Get full text
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RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response
Published in Leukemia (01-08-2017)“…Chromosomal region 1p22 is deleted in ⩾20% of multiple myeloma (MM) patients, suggesting the presence of an unidentified tumor suppressor. Using…”
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Differential expression of NF-[kappa]B target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism
Published in Leukemia (01-08-2010)“…Mucosa-associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1,…”
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Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing
Published in Leukemia (01-09-2016)Get full text
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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
Published in Nature genetics (01-10-2004)“…In T-cell acute lymphoblastic leukemia (T-ALL), transcription factors are known to be deregulated by chromosomal translocations, but mutations in protein…”
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Differential expression of NF-κB target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism
Published in Leukemia (01-08-2010)“…Mucosa-associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1,…”
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The accuracy of positron emission tomography in the detection of posttransplant lymphoproliferative disorder
Published in Haematologica (Roma) (01-05-2013)“…We investigated sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 18F-fluorodeoxyglucose-positron emission…”
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Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias
Published in Leukemia (01-04-2004)“…Detection of the FIP1L1-PDGFRA fusion gene or the corresponding cryptic 4q12 deletion supports the diagnosis of chronic eosinophilic leukemia (CEL) in patients…”
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FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations
Published in Leukemia (01-08-2005)“…The transcription factor Forkhead box protein P1 (FOXP1) is highly expressed in a proportion of diffuse large B-cell lymphoma (DLBCL). In this report, we…”
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Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia
Published in Leukemia (01-01-2009)“…Episomes with the NUP214-ABL1 fusion gene have been observed in 6% of T-ALL. In this multicentric study we collected 27 cases of NUP214-ABL1 -positive T-ALL…”
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A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation
Published in Leukemia (01-07-2007)“…The biologic and pathologic features of B-cell malignancies bearing a translocation t(14;19)(q32;q13) leading to a fusion of IGH and BCL3 are still poorly…”
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Translocation t(14;18) is not associated with inferior outcome in chronic lymphocytic leukemia
Published in Leukemia (01-06-2009)Get full text
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Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas
Published in Leukemia (01-11-2003)“…The recently discovered MLT/MALT1 gene is fused with the API2 gene in the t(11;18)(q21;q21), which characterizes about one-third of MALT lymphomas. In order to…”
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VH gene analysis of hairy cell leukemia reveals a homogeneous mutation status and suggests its marginal zone B-cell origin
Published in Leukemia (01-10-2004)Get full text
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Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL
Published in Leukemia (01-09-2007)Get full text
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Real-time reverse transcription-PCR and fluorescence in-situ hybridization are complementary to understand the mechanisms involved in HER-2/neu overexpression in human breast carcinomas
Published in Histopathology (01-04-2005)“…Aims : To evaluate the HER‐2/neu status at the mRNA and DNA level of breast carcinomas and to compare it with HER‐2/neu receptor overexpression by…”
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A new multicolor-FISH approach for the characterization of marker chromosomes : Centromere-specific multicolor-FISH (CenM-FISH)
Published in Human genetics (01-03-2001)“…Centromere-specific multi-color FISH (cenM-FISH) is a new multicolor FISH technique that allows the simultaneous characterization of all human centromeres by…”
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