Search Results - "Wixey, Julie A."

Early evolution of glial morphology and inflammatory cytokines following hypoxic-ischemic injury in the newborn piglet brain by Teo, Elliot J., Chand, Kirat. K., Miller, Stephanie M., Wixey, Julie A., Colditz, Paul B., Bjorkman, S. Tracey

“…Neuroinflammation is a hallmark of hypoxic-ischemic injury and can be characterized by the activation of glial cells and the expression of inflammatory…”
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Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain by Wixey, Julie A, Lee, Kah Meng, Miller, Stephanie M, Goasdoue, Kate, Colditz, Paul B, Tracey Bjorkman, S, Chand, Kirat K

“…The fetal brain is particularly vulnerable to intrauterine growth restriction (IUGR) conditions evidenced by neuronal and white matter abnormalities and…”
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Could serotonin play a role in abnormal brain outcomes in fetal growth restriction? by Beecher, Kate, Wixey, Julie

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Understanding the timing of brain injury in fetal growth restriction: lessons from a model of spontaneous growth restriction in piglets by Musco, Hannah, Wixey, Julie

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Improving brain outcomes in the growth restricted newborn: treating after birth by Wixey, Julie, Bjorkman, Stella

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Ibuprofen Treatment Reduces the Neuroinflammatory Response and Associated Neuronal and White Matter Impairment in the Growth Restricted Newborn by Wixey, Julie A, Sukumar, Kishen R, Pretorius, Rinaldi, Lee, Kah Meng, Colditz, Paul B, Bjorkman, S Tracey, Chand, Kirat K

“…Intrauterine growth restriction (IUGR) is a condition where the fetus does not achieve optimal growth, commonly caused by placental insufficiency. The chronic…”
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Editorial: Pathomechanisms and Treatments to Protect the Preterm, Fetal Growth Restricted and Neonatal Encephalopathic Brain by Fleiss, Bobbi, Murray, Deidre M., Bjorkman, S. Tracey, Wixey, Julie A.

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The search for blood biomarkers that indicate risk of adverse neurodevelopmental outcomes in fetal growth restriction by Musco, Hannah, Beecher, Kate, Chand, Kirat K, Boyd, Roslyn N, Colditz, Paul B, Wixey, Julie A

“…Fetal growth restriction (FGR) impacts 5%-10% of pregnancies and is associated with increased risk of mortality and morbidity. Although adverse…”
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Minocycline: A neuroprotective agent for hypoxic-ischemic brain injury in the neonate? by Buller, Kathryn M., Carty, Michelle L., Reinebrant, Hanna E., Wixey, Julie A.

“…Minocycline is a second‐generation tetracycline and a potential neuroprotective intervention following brain injury. However, despite the recognized beneficial…”
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Inhibition of Neuroinflammation Prevents Injury to the Serotonergic Network After Hypoxia-Ischemia in the Immature Rat Brain by Wixey, Julie A, Reinebrant, Hanna E, Buller, Kathryn M

“…The phenotypic identities and characterization of neural networks disrupted after neonatal hypoxia-ischemia (HI) in the preterm brain remain to be elucidated…”
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Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newborn by Chand, Kirat K., Patel, Jatin, Bjorkman, S. T., Sim, Seen-Ling, Miller, Stephanie M., Teo, Elliot, Jones, Lara, Sun, Jane, Colditz, Paul B., Khosrotehrani, Kiarash, Wixey, Julie A.

“…The foetal brain is particularly vulnerable to the detrimental effects of foetal growth restriction (FGR) with subsequent abnormal neurodevelopment being…”
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Hypoxia-ischemia in the immature rodent brain impairs serotonergic neuronal function in certain dorsal raphé nuclei by Reinebrant, Hanna, Wixey, Julie, Buller, Kathryn

“…Neonatal hypoxia-ischemia (HI) results in losses of serotonergic neurons in specific dorsal raphé nuclei. However, not all serotonergic raphé neurons are lost…”
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Post-insult Ibuprofen Treatment Attenuates Damage to the Serotonergic System After Hypoxia-Ischemia in the Immature Rat Brain by Wixey, Julie A, Reinebrant, Hanna E, Buller, Kathryn M

“…ABSTRACTThere is currently no therapeutic intervention to stem neonatal brain injury after exposure to hypoxia-ischemia (HI). Potential neuroprotective…”
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Targeting inflammation to reduce brain injury in growth restricted newborns： a potential treatment by Wixey, Julie A, Colditz, Paul B, Björkman, Stella Tracey

“…Introduction： Intrauterine growth restriction （IUGR） is commonly caused by placental insufficiency, resulting in a chronic hypoxic environment and subsequent…”
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Evidence that the serotonin transporter does not shift into the cytosol of remaining neurons after neonatal brain injury by Wixey, Julie A., Reinebrant, Hanna E., Buller, Kathryn M.

“…► Novel insights into regulation of serotonin after neonatal brain injury. ► Serotonin transporter stays at cell membrane after neonatal brain injury. ►…”
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Review: Neuroinflammation in intrauterine growth restriction by Wixey, Julie A, Chand, Kirat K, Colditz, Paul B, Bjorkman, S. Tracey

“…Abstract Disruption to the maternal environment during pregnancy from events such as hypoxia, stress, toxins, inflammation, and reduced placental blood flow…”
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Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis by Lewindon, Peter J., Puertolas-Lopez, Mora V., Ramm, Louise E., Noble, Charlton, Pereira, Tamara N., Wixey, Julie A., Hartel, Gunter F., Calvopina, Diego A., Leung, Daniel H., Ramm, Grant A.

“…Liver disease develops in 15%–72% of patients with cystic fibrosis, and 5%–10% develop cirrhosis or portal hypertension, usually during childhood. Transient…”
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Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model by Buller, Kathryn M., Wixey, Julie A., Reinebrant, Hanna E.

“…Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that…”
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Electroencephalographic studies in growth-restricted and small-for-gestational-age neonates by Stevenson, Nathan J., Lai, Melissa M., Starkman, Hava E., Colditz, Paul B., Wixey, Julie A.

“…Foetal growth restriction (FGR) and being born small for gestational age (SGA) are associated with neurodevelopmental delay. Early diagnosis of neurological…”
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Effects of fetal growth restriction on the perinatal neurovascular unit and possible treatment targets by Wu, Bing Anthony, Chand, Kirat K., Bell, Alexander, Miller, Suzanne L., Colditz, Paul B., Malhotra, Atul, Wixey, Julie A.

“…The neurovascular unit (NVU) within the brain is a multicellular unit that synergistically acts to maintain blood–brain barrier function and meet cerebral…”
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