Search Results - "Witzel, R"

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors by Caputo, Luca, Witzel, Hagen R., Kolovos, Petros, Cheedipudi, Sirisha, Looso, Mario, Mylona, Athina, van IJcken, Wilfred F.J., Laugwitz, Karl-Ludwig, Evans, Sylvia M., Braun, Thomas, Soler, Eric, Grosveld, Frank, Dobreva, Gergana

“…Cardiac stem/progenitor cells hold great potential for regenerative therapies; however, the mechanisms regulating their expansion and differentiation remain…”
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The LIM Protein Ajuba Restricts the Second Heart Field Progenitor Pool by Regulating Isl1 Activity by Witzel, Hagen R., Jungblut, Benno, Choe, Chong Pyo, Crump, J. Gage, Braun, Thomas, Dobreva, Gergana

“…Morphogenesis of the heart requires tight control of cardiac progenitor cell specification, expansion, and differentiation. Retinoic acid (RA) signaling…”
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Isl2b regulates anterior second heart field development in zebrafish by Witzel, Hagen R., Cheedipudi, Sirisha, Gao, Rui, Stainier, Didier Y. R., Dobreva, Gergana D.

“…After initial formation, the heart tube grows by addition of second heart field progenitor cells to its poles. The transcription factor Isl1 is expressed in…”
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TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function by Alam, Muhammad S., Gaida, Matthias M., Witzel, Hagen R., Otsuka, Shizuka, Abbasi, Aamna, Guerin, Theresa, Abdelmaksoud, Abdalla, Wong, Nathan, Cam, Margaret C., Kozlov, Serguei, Ashwell, Jonathan D.

“…Pancreatic adenocarcinoma (PDAC) is one the most intractable cancers, in part due to its highly inflammatory microenvironment and paucity of infiltrating…”
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Inhibition of the Cyclin K‐CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer by Frei, Katharina, Schecher, Sabrina, Daher, Tamas, Hörner, Nina, Richter, Jutta, Hildebrand, Ute, Schindeldecker, Mario, Witzel, Hagen R., Tsaur, Igor, Porubsky, Stefan, Gaida, Matthias M., Roth, Wilfried, Tagscherer, Katrin E.

“…Androgen deprivation therapy (ADT) is the mainstay of the current first‐line treatment concepts for patients with advanced prostate carcinoma (PCa). However,…”
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Perilipin 1 Expression Differentiates Liposarcoma from Other Types of Soft Tissue Sarcoma by Straub, Beate K., Witzel, Hagen R., Pawella, Lena M., Renner, Marcus, Eiteneuer, Eva, Hashani, Merita, Schirmacher, Peter, Roth, Wilfried, Mechtersheimer, Gunhild

“…Lipid droplets, a morphologic feature of adipocytic tumors, are strongly regulated by associated proteins of the perilipin/PAT (perilipin, adipophilin, and…”
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Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging in Pancreatic Cancer is Associated with Tumor Hypoxia by Mayer, Philipp, Kraft, Anne, Witzel, Hagen R, Marnet, Nicole, Hörner, Nina, Roth, Wilfried, Heinrich, Stefan, Hackert, Thilo, Bergmann, Frank, Kauczor, Hans-Ulrich, Klauss, Miriam, Gaida, Matthias M

“…Hypoxia is a hallmark of pancreatic cancer (PDAC) due to its compact and extensive fibrotic tumor stroma. Hypoxia contributes to high lethality of this…”
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N-Cadherin Distinguishes Intrahepatic Cholangiocarcinoma from Liver Metastases of Ductal Adenocarcinoma of the Pancreas by Gerber, Tiemo S., Goeppert, Benjamin, Hausen, Anne, Witzel, Hagen R., Bartsch, Fabian, Schindeldecker, Mario, Gröger, Lisa-Katharina, Ridder, Dirk A., Cahyadi, Oscar, Esposito, Irene, Gaida, Matthias M., Schirmacher, Peter, Galle, Peter R., Lang, Hauke, Roth, Wilfried, Straub, Beate K.

“…Carcinomas of the pancreatobiliary system confer an especially unfavorable prognosis. The differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and…”
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N-glycan charge assay--an alternative for potency assays of therapeutic glycoproteins? by Hermentin, P, Witzel, R, Schwick-Wagner, P, Blumrich, M

“…A new in vitro potency assay for erythropoietin has been developed and compared to the exhypoxic polycythemic mouse bioassay for rhuEPO batch release, required…”
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A strategy for the mapping of N-glycans by high-performance capillary electrophoresis by Hermentin, P, Doenges, R, Witzel, R, Hokke, C H, Vliegenthart, J F, Kamerling, J P, Conradt, H S, Nimtz, M, Brazel, D

“…We have evaluated high-performance capillary electrophoresis (HPCE) with respect to its suitability for use in establishing a carbohydrate-mapping database…”
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Evaluation of whiteness by Grum, F, Witzel, R F

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Role of eye movements in the perception of apparent motion by Kintz, R T, Witzel, R F

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The Hypothetical N-Glycan Charge. A Number to Characterize Protein N-Glycosylation by HERMENTIN, P., WITZEL, R.

“…We investigated the usefulness of Z determination as an analytical tool to assess the glycosylation of recombinant glycoproteins during early research,…”
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Threshold and suprathreshold perceptual color differences by Witzel, R F, Burnham, R W, Onley, J W

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Exploratory investigation of perceptual color scaling by Burnham, R W, Onley, J W, Witzel, R F

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Online Prediction of Berlin Single-Family House Prices by Schulz, Rainer, Sofyan, Hizir, Werwatz, Axel, Witzel, Rodrigo

“…SummarySingle-family houses are typically the most important component in their owners’ portfolios. Buying a home is a major financial transaction for most…”
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The hypothetical N-glycan charge: a number that characterizes protein glycosylation by Hermentin, Peter, Witzel, Reinhild, Kanzy, Ernst-Jürgen, Diderrich, Gaston, Hoffmann, Dieter, Metzner, Hubert, Vorlop, Jürgen, Haupt, Heinz

“…The production of recombinant glycoprotein therapeutics requires characterization of glycosylation with respect to the lot-to-lot consistency. Here we…”
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A strategy for the mapping of N-glycans by high-pH anion-exchange chromatography with pulsed amperometric detection by Hermentin, P, Witzel, R, Vliegenthart, J F, Kamerling, J P, Nimtz, M, Conradt, H S

“…We have evaluated the high-pH anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) with respect to its suitability to establish a…”
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Literature Awareness among Health Staff in Developing Countries by Weitzel, Rolf

“…Discusses the lack of professional literature awareness on the part of health care professionals in developing countries. Topics addressed include symptoms and…”
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The mapping by high-pH anion-exchange chromatography with pulsed amperometric detection and capillary electrophoresis of the carbohydrate moieties of human plasma alpha 1-acid glycoprotein by Hermentin, P, Witzel, R, Doenges, R, Bauer, R, Haupt, H, Patel, T, Parekh, R B, Brazel, D

“…The reducing oligosaccharides released from alpha 1-acid glycoprotein (AGP) by conventional hydrazinolysis have been analyzed by two different mapping…”
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