Search Results - "Witz, Guillaume"

Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism by Witz, Guillaume, van Nimwegen, Erik, Julou, Thomas

“…Living cells proliferate by completing and coordinating two cycles, a division cycle controlling cell size and a DNA replication cycle controlling the number…”
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DNA supercoiling and its role in DNA decatenation and unknotting by Witz, Guillaume, Stasiak, Andrzej

“…Chromosomal and plasmid DNA molecules in bacterial cells are maintained under torsional tension and are therefore supercoiled. With the exception of extreme…”
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Four-Dimensional Imaging of E. coli Nucleoid Organization and Dynamics in Living Cells by Fisher, Jay K., Bourniquel, Aude, Witz, Guillaume, Weiner, Beth, Prentiss, Mara, Kleckner, Nancy

“…Visualization of living E. coli nucleoids, defined by HupA-mCherry, reveals a discrete, dynamic helical ellipsoid. Three basic features emerge. (1) Nucleoid…”
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Chromosomes Progress to Metaphase in Multiple Discrete Steps via Global Compaction/Expansion Cycles by Liang, Zhangyi, Zickler, Denise, Prentiss, Mara, Chang, Frederick S., Witz, Guillaume, Maeshima, Kazuhiro, Kleckner, Nancy

“…Mammalian mitotic chromosome morphogenesis was analyzed by 4D live-cell and snapshot deconvolution fluorescence imaging. Prophase chromosomes, whose…”
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Persistence length and scaling properties of single-stranded DNA adsorbed on modified graphite by Rechendorff, Kristian, Witz, Guillaume, Adamcik, Jozef, Dietler, Giovanni

“…We have characterized the polymer physics of single-stranded DNA (ssDNA) using atomic force microscopy. The persistence length l(p) of circular ssDNA adsorbed…”
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Tightening of DNA knots by supercoiling facilitates their unknotting by type II DNA topoisomerases by Witz, Guillaume, Dietler, Giovanni, Stasiak, Andrzej, Kleckner, Nancy E.

“…Using numerical simulations, we compare properties of knotted DNA molecules that are either torsionally relaxed or supercoiled. We observe that DNA…”
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Conformation of circular DNA in two dimensions by Witz, Guillaume, Rechendorff, Kristian, Adamcik, Jozef, Dietler, Giovanni

“…The conformation of circular DNA molecules of various lengths adsorbed in a 2D conformation on a mica surface is studied. The results confirm the conjecture…”
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Fractal dimension and localization of DNA knots by Ercolini, Erika, Valle, Francesco, Adamcik, Jozef, Witz, Guillaume, Metzler, Ralf, De Los Rios, Paolo, Roca, Joaquim, Dietler, Giovanni

“…The scaling properties of DNA knots of different complexities were studied by atomic force microscope. Following two different protocols DNA knots are adsorbed…”
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Observation of single-stranded DNA on mica and highly oriented pyrolytic graphite by atomic force microscopy by Adamcik, Jozef, Klinov, Dmitry V., Witz, Guillaume, Sekatskii, Sergey K., Dietler, Giovanni

“…Atomic force microscopy was used to image single-stranded DNA (ssDNA) adsorbed on mica modified by Mg 2+, by 3-aminopropyltriethoxysilane or on modified highly…”
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Assessing dystrophies and other muscle diseases at the nanometer scale by atomic force microscopy by van Zwieten, Ruthger W, Puttini, Stefania, Lekka, Małgorzata, Witz, Guillaume, Gicquel-Zouida, Evelyne, Richard, Isabelle, Lobrinus, Johannes A, Chevalley, François, Brune, Harald, Dietler, Giovanni, Kulik, Andrzej, Kuntzer, Thierry, Mermod, Nicolas

“…Atomic force microscopy nanoindentation of myofibers was used to assess and quantitatively diagnose muscular dystrophies from human patients. Myofibers were…”
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DNA knots and DNA supercoiling by Witz, Guillaume, Dietler, Giovanni, Stasiak, Andrzej

“…Comment on: Witz G, et al. Proc Natl Acad Sci USA 2011; 108:3608-11…”
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Automated detecting, segmenting and measuring of grains in images of fluvial sediments: The potential for large and precise data from specialist deep learning models and transfer learning by Mair, David, Witz, Guillaume, Do Prado, Ariel Henrique, Garefalakis, Philippos, Schlunegger, Fritz

“…The size of sedimentary particles in rivers bears information on the sediment entrainment or deposition mechanisms and the hydraulic conditions controlling…”
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CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin by Bruggisser, Julia, Tarek, Basma, Wyder, Marianne, Müller, Philipp, von Ballmoos, Christoph, Witz, Guillaume, Enzmann, Gaby, Deutsch, Urban, Engelhardt, Britta, Posthaus, Horst

“…Clostridium perfringens β-toxin (CPB) is a highly active β-pore-forming toxin (β-PFT) and the essential virulence factor for fatal, necro-hemorrhagic enteritis…”
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CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms by Khosrozadeh, Amin, Seeger, Raphaela, Witz, Guillaume, Radecke, Julika, Sørensen, Jakob B, Zuber, Benoît

“…Cryo-electron tomography (cryo-ET) has the potential to reveal cell structure down to atomic resolution. Nevertheless, cellular cryo-ET data is highly complex,…”
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Immune cell extravasation in an organ-on-chip to model lung inflammation by van Os, Lisette, Yeoh, Jeremy, Witz, Guillaume, Ferrari, Dario, Krebs, Philippe, Chandorkar, Yashoda, Zeinali, Soheila, Sengupta, Arunima, Guenat, Olivier T.

“…Acute respiratory distress syndrome (ARDS) is a severe lung condition with high mortality and various causes, including lung infection. No specific treatment…”
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Chromosome Capture Brings It All Together by Kleckner, Nancy, Zickler, Denise, Witz, Guillaume

“…A simple, robust model explains higher-order organization of mammalian chromosomes. [Also see Research Article by Naumova et al. ] The organization and…”
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The bacterial nucleoid: nature, dynamics and sister segregation by Kleckner, Nancy, Fisher, Jay K, Stouf, Mathieu, White, Martin A, Bates, David, Witz, Guillaume

“…Highlights • The nucleoid is self-adherent and helical ellipsoidal via radial plectoneme loops. • The nucleoid is viscoelastic with ATP-mediated enhancement of…”
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Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa by Rhoades, Nicholas, Nguyen, Tinh-Suong, Witz, Guillaume, Cecere, Germano, Hammond, Thomas, Mazur, Alexey K., Gladyshev, Eugene

“…The pairing of homologous chromosomes represents a critical step of meiosis in nearly all sexually reproducing species. In many organisms, pairing involves…”
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Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier by Castro Dias, Mariana, Odriozola Quesada, Adolfo, Soldati, Sasha, Bösch, Fabio, Gruber, Isabelle, Hildbrand, Tobias, Sönmez, Derya, Khire, Tejas, Witz, Guillaume, McGrath, James L, Piontek, Jörg, Kondoh, Masuo, Deutsch, Urban, Zuber, Benoît, Engelhardt, Britta

“…The migration of activated T cells across the blood-brain barrier (BBB) is a critical step in central nervous system (CNS) immune surveillance and…”
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Molecular biology. Chromosome capture brings it all together by Kleckner, Nancy, Zickler, Denise, Witz, Guillaume

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