Search Results - "Wittkowsky, Ann K."

An analysis of the relative effects of VKORC1 and CYP2C9 variants on anticoagulation related outcomes in warfarin-treated patients by Meckley, Lisa M, Wittkowsky, Ann K, Rieder, Mark J, Rettie, Allan E, Veenstra, David L

“…The objective of this study was to assess the relative influence of VKORC1 and CYP2C9 genetic variants on several clinical outcomes related to warfarin…”
Get more information

Outcomes of oral anticoagulant therapy managed by telephone vs in-office visits in an anticoagulation clinic setting by Wittkowsky, Ann K, Nutescu, Edith A, Blackburn, Juan, Mullins, Jennifer, Hardman, Jennifer, Mitchell, Jessica, Vats, Vikrant

“…Anticoagulation management by a dedicated anticoagulation clinic improves patient outcomes compared to routine medical care. Telephone-based anticoagulation…”
Get more information

Guidance for the practical management of the heparin anticoagulants in the treatment of venous thromboembolism by Smythe, Maureen A., Priziola, Jennifer, Dobesh, Paul P., Wirth, Diane, Cuker, Adam, Wittkowsky, Ann K.

“…Venous thromboembolism (VTE) is a serious and often fatal medical condition with an increasing incidence. Despite the changing landscape of VTE treatment with…”
Get full text

Novel Oral Anticoagulants and Their Role in Clinical Practice by Wittkowsky, Ann K.

“…The complexities of oral anticoagulation with warfarin have led to the search for more practical alternative agents. Novel direct factor IIa inhibitors and…”
Get full text

Direct Thrombin Inhibitors for Anticoagulation by Nutescu, Edith A, Wittkowsky, Ann K

“…OBJECTIVE: To review the progress in developing direct thrombin inhibitors (DTIs) for anticoagulation within the context of existing anticoagulation therapies…”
Get full text

Warfarin-related outcomes in patients with antiphospholipid antibody syndrome managed in an anticoagulation clinic by Wittkowsky, Ann K, Downing, Jennifer, Blackburn, Juan, Nutescu, Edith

“…Patients with antiphospholipid antibody syndrome (APA) are at elevated risk of venous and arterial thromboembolic complications. Oral anticoagulation with…”
Get more information

Managing transitions from oral factor Xa inhibitors to unfractionated heparin infusions by Faust, Andrew C, Kanyer, Dave, Wittkowsky, Ann K

“…PURPOSEPublished evidence regarding the effects of oral factor Xa inhibitors on anticoagulation monitoring tests is reviewed with a focus on monitoring…”
Get full text

Anticoagulation Monitoring Part 2: Unfractionated Heparin and Low-Molecular-Weight Heparin by Spinler, Sarah A, Wittkowsky, Ann K, Nutescu, Edith A, Smythe, Maureen A

“…OBJECTIVE To review the availability, mechanisms, limitations, and clinical application of point-of-care (POC) devices used in monitoring anticoagulation with…”
Get full text

New oral anticoagulants: a practical guide for clinicians by Wittkowsky, Ann K.

“…The search for an oral anticoagulant with acceptable efficacy and safety in the treatment and prevention of venous and arterial thromboembolism, but with…”
Get full text

Survey of pharmacist-managed inpatient anticoagulation services by Phillips, Katherine W, Wittkowsky, Ann K

“…The scope of existing pharmacist-managed inpatient anticoagulation services and the roles and responsibilities of the pharmacists involved were studied. A…”
Get full text

Impact of target-specific oral anticoagulants on transitions of care and outpatient care models by Wittkowsky, Ann K.

“…Patients with acute or chronic illness experience transitions of care when they leave one healthcare setting and move to another. Care transitions are points…”
Get full text

Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy by Higashi, Mitchell K, Veenstra, David L, Kondo, L. Midori, Wittkowsky, Ann K, Srinouanprachanh, Sengkeo L, Farin, Fred M, Rettie, Allan E

“…CONTEXT Warfarin is a commonly used anticoagulant that requires careful clinical management to balance the risks of overanticoagulation and bleeding with those…”
Get full text

Dietary supplements, herbs and oral anticoagulants: the nature of the evidence by Wittkowsky, Ann K.

“…In the US, the use of dietary supplements, including vitamins, minerals, amino acids, and herbal products, is extensive. Nonetheless, the majority of patients…”
Get full text

Delivery of Optimized Inpatient Anticoagulation Therapy: Consensus Statement from the Anticoagulation Forum by Nutescu, Edith A, Wittkowsky, Ann K, Burnett, Allison, Merli, Geno J, Ansell, Jack E, Garcia, David A

“…OBJECTIVE To provide recommendations for optimized anticoagulant therapy in the inpatient setting and outline broad elements that need to be in place for…”
Get full text

Argatroban for prevention and treatment of thromboembolism in heparin-induced thrombocytopenia by Kondo, LM, Wittkowsky, AK, Wiggins, BS

“…OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, adverse events, and cost of argatroban in the prevention and treatment of thromboembolism in…”
Get full text

Delivery of Optimized Anticoagulant Therapy: Consensus Statement from the Anticoagulation Forum by Garcia, David A, Witt, Daniel M, Hylek, Elaine, Wittkowsky, Ann K, Nutescu, Edith A, Jacobson, Alan, Moll, Stephan, Merli, Geno J, Crowther, Mark, Earl, Laura, Becker, Richard C, Oertel, Lynn, Jaffer, Amir, Ansell, Jack E

“…Objective: To provide recommendations, policies, and procedures pertaining to the provision of optimized anticoagulation therapy designed to achieve desired…”
Get full text

Rivaroxaban: Practical Considerations for Ensuring Safety and Efficacy by Smythe, Maureen A., Fanikos, John, Gulseth, Michael P., Wittkowsky, Ann K., Spinler, Sarah A., Dager, William E., Nutescu, Edith A.

“…Rivaroxaban is the first agent available within a new class of anticoagulants called direct factor Xa inhibitors. Rivaroxaban is approved for use in the United…”
Get full text

Dabigatran Etexilate in Clinical Practice: Confronting Challenges to Improve Safety and Effectiveness by Gulseth, Michael P., Wittkowsky, Ann K., Fanikos, John, Spinler, Sarah A., Dager, William E., Nutescu, Edith A.

“…A number of novel anticoagulants are moving through various stages of drug development. Recently, the United States Food and Drug Administration approved the…”
Get full text

Effective anticoagulation therapy: defining the gap between clinical studies and clinical practice by Wittkowsky, Ann K

“…Atrial fibrillation (AF) greatly increases the risk of stroke. Long-term oral therapy with warfarin reduces the risk of AF-related stroke by 62%, and national…”
Get full text

Treatment of venous thromboembolism: Adherence to guidelines and impact of physician knowledge, attitudes, and beliefs by Caprini, Joseph A., Tapson, Victor F., Hyers, Thomas M., Waldo, Albert L., Wittkowsky, Ann K., Friedman, Richard, Colgan, Kevin J., Shillington, Alicia C.

“…To assess the treatment of venous thromboembolism (VTE) in hospitalized patients enrolled in a national, multicenter database. This was a retrospective, cohort…”
Get full text