Search Results - "Witte, Irene"

The ability of the high-throughput comet assay to measure the sensitivity of five cell lines toward methyl methanesulfonate, hydrogen peroxide, and pentachlorophenol by Stang, Andre, Witte, Irene

“…A new, high-throughput version of the comet assay was developed using human fibroblasts (Stang and Witte, 2009). The present study examines the suitability of…”
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DNA damage induced by cis- and carboplatin as indicator for in vitro sensitivity of ovarian carcinoma cells by Unger, Florian T, Klasen, Hermann A, Tchartchian, Garri, de Wilde, Rudy L, Witte, Irene

“…The DNA damage by platinum cytostatics is thought to be the main cause of their cytotoxicity. Therefore the measurement of the DNA damage induced by cis- and…”
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Feasibility of strip-tillage for field grown vegetables by Annegret Übelhör, Irene Witte, Norbert Billen, Sabine Gruber, Wilfried Hermann, Jörg Morhard, Wilhelm Claupein

“…Row crops and field grown vegetables, such as white cabbage (Brassica oleracea convar. capitata var. alba), are affected by soil erosion caused by rainfall…”
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Prediction of individual response to anticancer therapy: historical and future perspectives by Unger, Florian T, Witte, Irene, David, Kerstin A

“…Since the introduction of chemotherapy for cancer treatment in the early 20th century considerable efforts have been made to maximize drug efficiency and at…”
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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

“…Stick it! A microelectrochemical method was developed for in situ manipulation of the cell‐adhesive property of an oligo(ethylene glycol)‐terminated…”
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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part III: The Comet Assay as an Alternative to In Vitro Clastogenicity Tests for Early Drug Candidate Selection by Witte, Irene, Plappert, Ulla, de Wall, Hartmut, Hartmann, Andreas

“…Early screening of drug candidates for genotoxicity typically includes an analysis for mutagenicity in bacteria and for clastogenicity in cultured mammalian…”
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Multi-site, multi-crop measurements in the soil–vegetation–atmosphere continuum: a comprehensive dataset from two climatically contrasting regions in southwestern Germany for the period 2009–2018 by Weber, Tobias K. D, Ingwersen, Joachim, Högy, Petra, Poyda, Arne, Wizemann, Hans-Dieter, Demyan, Michael Scott, Bohm, Kristina, Eshonkulov, Ravshan, Gayler, Sebastian, Kremer, Pascal, Laub, Moritz, Nkwain, Yvonne Funkiun, Troost, Christian, Witte, Irene, Reichenau, Tim, Berger, Thomas, Cadisch, Georg, Müller, Torsten, Fangmeier, Andreas, Wulfmeyer, Volker, Streck, Thilo

“…We present a comprehensive, high-quality dataset characterizing soil–vegetation and land surface processes from continuous measurements conducted in two…”
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Microelectrochemical Modulation of Micropatterned Cellular Environments by Zhao, Chuan, Zawisza, Izabella, Nullmeier, Martina, Burchardt, Malte, Träuble, Markus, Witte, Irene, Wittstock, Gunther

“…Patterned cell cultures obtained by microcontact printing have been modified in situ by a microelectrochemical technique. It relies on lifting cell-repellent…”
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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

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DNA Strand Break Induction and Enhanced Cytotoxicity of Propyl Gallate in the Presence of Copper(II) by Jacobi, Heike, Eicke, Britta, Witte, Irene

“…The antioxidant propyl gallate (PG) induced single strand breaks in PM2 DNA at concentrations higher than 0.25 μM when it was combined with copper…”
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Differences in genotoxicity of H2O2 and tetrachlorohydroquinone in human fibroblasts by PURSCHKE, Martin, JACOBI, Heike, WITTE, Irene

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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

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Differences in genotoxicity of H 2O 2 and tetrachlorohydroquinone in human fibroblasts by Purschke, Martin, Jacobi, Heike, Witte, Irene

“…During autoxidation of the pentachlorophenol (PCP) metabolite tetrachlorohydroquinone (TCHQ) the semiquinone is formed as well as reactive oxygen species…”
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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

“…Festgeklebt! Mit der hier vorgestellten mikroelektrochemischen Methode lassen sich das Zelladhäsionsverhalten eines Substrats aus einer…”
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Protection by desferrioxamine and other hydroxamic acids against tetrachlorohydroquinone-induced cyto- and genotoxicity in human fibroblasts by Witte, Irene, Zhu, Ben-Zhan, Lueken, Aloys, Magnani, Dino, Stossberg, Helge, Chevion, Mordechai

“…Tetrachlorohydroquinone (TCHQ) has been identified as a major toxic metabolite of the widely used wood preservative pentachlorophenol and has also been…”
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Induction of lipid peroxidation in human fibroblasts by the antioxidant propyl gallate in combination with copper(II) by Jacobi, Heike, Hinrichsen, Marie-Luise, Weß, Doris, Witte, Irene

“…The antioxidant propyl gallate (PG) induced lipid peroxidation in combination with non-toxic Cu(II) concentrations in human fibroblasts. This was measured by…”
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Correlation of Synergistic Cytotoxic Effects of Environmental Chemicals in Human Fibroblast with Their Lipophilicity by Witte, Irene, Jacobi, Heike, Juhl-Strauss, Ursula

“…Environmental chemicals with different log octanol water partition coefficient values at no-observed-effects concentrations were investigated in terms of the…”
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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

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Switching On Cell Adhesion with Microelectrodes by Zhao, Chuan, Witte, Irene, Wittstock, Gunther

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Correlation of synergistic cytotoxic effects of environmental chemicals in human fibroblasts with their lipophilicity by Witte, Irene, Jacobi, Heike, Juhl-Strauss, Ursula

“…The cytotoxic combination effects of 2,4-D with 12 xenobiotics having different lipophilicity were investigated in human fibroblasts at their no effect…”
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