Search Results - "Witte, A Mde"

Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine: e0125898 by Zhang, Yifan, Kecskes, Angela, Copmans, Danieelle, Langlois, Melanie, Crawford, Alexander D, Ceulemans, Berten, Lagae, Lieven, Witte, A Mde, Esguerra, Camila V

“…Dravet syndrome (DS) is one of the most pharmacoresistant and devastating forms of childhood epilepsy syndromes. Distinct de novo mutations in the SCN1A gene…”
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Insights from Zebrafish and Mouse Models on the Activity and Safety of Ar-Turmerone as a Potential Drug Candidate for the Treatment of Epilepsy: e81634 by Orellana-Paucar, Adriana Monserrath, Afrikanova, Tatiana, Thomas, Joice, Aibuldinov, Yelaman K, Dehaen, Wim, Witte, A Mde, Esguerra, Camila V

“…In a previous study, we uncovered the anticonvulsant properties of turmeric oil and its sesquiterpenoids (ar-turmerone, alpha -, beta -turmerone and alpha…”
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A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling: e83293 by Gebruers, Evelien, Cordero-Maldonado, Maria Lorena, Gray, Alexander I, Clements, Carol, Harvey, Alan L, Edrada-Ebel, Ruangelie, Witte, A Mde, Crawford, Alexander D, Esguerra, Camila V

“…Zebrafish have recently emerged as an attractive model for the in vivo bioassay-guided isolation and characterization of pharmacologically active small…”
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Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products. e64006 by Bohni, Nadine, Cordero-Maldonado, Maria Lorena, Maes, Jan, Siverio-Mota, Dany, Marcourt, Laurence, Munck, Sebastian, Kamuhabwa, Appolinary R, Moshi, Mainen J, Esguerra, Camila V, Witte, A Mde

“…Natural products (NPs) are an attractive source of chemical diversity for small-molecule drug discovery. Several challenges nevertheless persist with respect…”
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