Search Results - "Witt, Tyra"
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Characterization of a Resident Population of Adventitial Macrophage Progenitor Cells in Postnatal Vasculature
Published in Circulation research (18-07-2014)“…RATIONALE:Macrophages regulate blood vessel structure and function in health and disease. The origins of tissue macrophages are diverse, with evidence for…”
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2
Pulmonary Biodistribution of Platelet-Derived Regenerative Exosomes in a Porcine Model
Published in International journal of molecular sciences (24-02-2024)“…The purpose of this study was to evaluate the biodistribution of a platelet-derived exosome product (PEP), previously shown to promote regeneration in the…”
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3
Feasibility of selective cardiac ventricular electroporation
Published in PloS one (21-02-2020)“…The application of brief high voltage electrical pulses to tissue can lead to an irreversible or reversible electroporation effect in a cell-specific manner…”
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Low-Dose Gamma Irradiation of Decellularized Heart Valves Results in Tissue Injury In Vitro and In Vivo
Published in The Annals of thoracic surgery (01-02-2016)“…Background Decellularized heart valves are emerging as a potential alternative to current bioprostheses for valve replacement. Whereas techniques of…”
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5
[89Zr]Zr-DBN labeled cardiopoietic stem cells proficient for heart failure
Published in Nuclear medicine and biology (01-11-2020)“…Radiolabeling of stem cells with a positron emitting radioisotope represents a major advancement in regenerative biotherapy enabling non-invasive imaging. To…”
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Identification of a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Adventitia of Postnatal Murine Aorta
Published in Circulation (New York, N.Y.) (31-01-2012)“…Hematopoiesis originates from the dorsal aorta during embryogenesis. Although adult blood vessels harbor progenitor populations for endothelial and smooth…”
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Elimination of Purkinje Fibers by Electroporation Reduces Ventricular Fibrillation Vulnerability
Published in Journal of the American Heart Association (07-08-2018)“…Background The Purkinje network appears to play a pivotal role in the triggering as well as maintenance of ventricular fibrillation. Irreversible…”
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Vasculogenic properties of adventitial Sca-1+CD45+ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis
Published in Scientific reports (13-05-2019)“…The cellular origins of vasa vasorum are ill-defined and may involve circulating or local progenitor cells. We previously discovered that murine aortic…”
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Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence
Published in npj Regenerative medicine (29-09-2022)“…Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these…”
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Nanoparticle-Mediated Cell Capture Enables Rapid Endothelialization of a Novel Bare Metal Stent
Published in Tissue engineering. Part A (01-07-2018)“…Incomplete endothelialization of intracoronary stents has been associated with stent thrombosis and recurrent symptoms, whereas prolonged use of dual…”
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Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate
Published in PloS one (24-11-2014)“…The family of natriuretic peptides (NPs), including atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and C-type natriuretic peptide (CNP),…”
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12
Infliximab Limits Injury in Myocardial Infarction
Published in Journal of the American Heart Association (07-05-2024)“…The purpose of this study was to investigate a therapeutic approach targeting the inflammatory response and consequent remodeling from ischemic myocardial…”
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13
M 3 RNA Drives Targeted Gene Delivery in Acute Myocardial Infarction
Published in Tissue engineering. Part A (01-01-2019)“…The M RNA (microencapsulated modified messenger RNA) platform is an approach to deliver messenger RNA (mRNA) in vivo, achieving a nonintegrating and viral-free…”
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14
Magnetically Targeted Endothelial Cell Localization in Stented Vessels
Published in Journal of the American College of Cardiology (07-11-2006)“…Magnetically Targeted Endothelial Cell Localization in Stented Vessels Sorin V. Pislaru, Adriana Harbuzariu, Rajiv Gulati, Tyra Witt, Nicole P. Sandhu, Robert…”
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Magnetic forces enable rapid endothelialization of synthetic vascular grafts
Published in Circulation (New York, N.Y.) (04-07-2006)“…Synthetic vascular grafts cannot be used in small vessels because of graft failure caused by thrombosis and neointima formation. Rapid endothelialization may…”
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Autologous culture-modified mononuclear cells confer vascular protection after arterial injury
Published in Circulation (New York, N.Y.) (23-09-2003)“…Bone marrow-derived cells have been shown to contribute to endothelial replacement after vascular injury. In vitro culture of peripheral blood mononuclear…”
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Author Correction: Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence
Published in npj Regenerative medicine (31-10-2022)Get full text
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18
Intravascular Delivery of Biologics to the Rat Kidney
Published in Journal of visualized experiments (01-09-2016)“…The renal microvascular compartment plays an important role in the progression of kidney disease and hypertension, leading to the development of End Stage…”
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Tissue Factor Pathway Inhibitor Blocks Angiogenesis via Its Carboxyl Terminus
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2012)“…OBJECTIVE—Tissue factor pathway inhibitor (TFPI) is the primary regulator of the tissue factor (TF) coagulation pathway. As such, TFPI may regulate the…”
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Xenoantigenicity of porcine decellularized valves
Published in Journal of cardiothoracic surgery (17-07-2017)“…The xenoantigenicity of porcine bioprosthetic valves is implicated as an etiology leading to calcification and subsequent valve failure. Decellularization of…”
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