Search Results - "Witt, S. H."

Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients by Frank, J, Lang, M, Witt, S H, Strohmaier, J, Rujescu, D, Cichon, S, Degenhardt, F, Nöthen, M M, Collier, D A, Ripke, S, Naber, D, Rietschel, M

Get full text

Epigenetic signatures in antidepressant treatment response: a methylome-wide association study in the EMC trial by Engelmann, J., Zillich, L., Frank, J., Wagner, S., Cetin, M., Herzog, D. P., Müller, M. B., Tadic, A., Foo, J. C., Sirignano, L., Braus, D. F., Dahmen, N., Sordon, S., Riemenschneider, M., Spaniol, C., Gasparoni, G., Rietschel, M., Witt, S. H., Lieb, K., Streit, F.

“…Although the currently available antidepressants are well established in the treatment of the major depressive disorder (MDD), there is strong variability in…”
Get full text

Effects of a genome-wide supported psychosis risk variant on neural activation during a theory-of-mind task by Walter, H, Schnell, K, Erk, S, Arnold, C, Kirsch, P, Esslinger, C, Mier, D, Schmitgen, M M, Rietschel, M, Witt, S H, Nöthen, M M, Cichon, S, Meyer-Lindenberg, A

“…Schizophrenia is associated with marked deficits in theory of mind (ToM), a higher-order form of social cognition representing the thoughts, emotions and…”
Get full text

Oxytocin receptor polymorphism and childhood social experiences shape adult personality, brain structure and neural correlates of mentalizing by Schneider-Hassloff, H., Straube, B., Jansen, A., Nuscheler, B., Wemken, G., Witt, S.H., Rietschel, M., Kircher, T.

“…The oxytocin system is involved in human social behavior and social cognition such as attachment, emotion recognition and mentalizing (i.e. the ability to…”
Get full text

Effects of a CACNA1C genotype on attention networks in healthy individuals by Thimm, M, Kircher, T, Kellermann, T, Markov, V, Krach, S, Jansen, A, Zerres, K, Eggermann, T, Stöcker, T, Shah, N J, Nöthen, M M, Rietschel, M, Witt, S H, Mathiak, K, Krug, A

“…Recent genetic studies found the A allele of the variant rs1006737 in the alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene to be…”
Get more information

The CACNA1C risk variant for bipolar disorder influences limbic activity by Wessa, M, Linke, J, Witt, S H, Nieratschker, V, Esslinger, C, Kirsch, P, Grimm, O, Hennerici, M G, Gass, A, King, A V, Rietschel, M

Get full text

The psychiatric vulnerability gene CACNA1C and its sex-specific relationship with personality traits, resilience factors and depressive symptoms in the general population by Strohmaier, J, Amelang, M, Hothorn, L A, Witt, S H, Nieratschker, V, Gerhard, D, Meier, S, Wüst, S, Frank, J, Loerbroks, A, Rietschel, M, Stürmer, T, Schulze, T G

“…Genome-wide association studies have reported an association between the A-allele of rs1006737 within CACNA1C and affective disorders and schizophrenia. The…”
Get full text

Effects of BDNF Val66Met genotype and schizophrenia familial risk on a neural functional network for cognitive control in humans by Schweiger, J. I., Bilek, E., Schäfer, A., Braun, U., Moessnang, C., Harneit, A., Post, P., Otto, K., Romanczuk-Seiferth, N., Erk, S., Wackerhagen, C., Mattheisen, M., Mühleisen, T. W., Cichon, S., Nöthen, M. M., Frank, J., Witt, S. H., Rietschel, M., Heinz, A., Walter, H., Meyer-Lindenberg, A., Tost, H.

“…Cognitive control represents an essential neuropsychological characteristic that allows for the rapid adaption of a changing environment by constant…”
Get full text

Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate by Kiefer, F, Witt, S H, Frank, J, Richter, A, Treutlein, J, Lemenager, T, Nöthen, M M, Cichon, S, Batra, A, Berner, M, Wodarz, N, Zimmermann, U S, Spanagel, R, Wiedemann, K, Smolka, M N, Heinz, A, Rietschel, M, Mann, K

“…In alcoholism, both relapse to alcohol drinking and treatment response are suggested to be genetically modulated. This study set out to determine whether the…”
Get full text

Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning by Pohlack, S T, Nees, F, Ruttorf, M, Witt, S H, Nieratschker, V, Rietschel, M, Flor, H

Get full text

Genetic Risk For Nicotine Dependence in the Cholinergic System and Activation of the Brain Reward System in Healthy Adolescents by NEES, F, WITT, S. H, FRANK, J, GALLINAT, J, GARAVAN, H, HEINZ, A, ITTERMANN, B, LOTH, E, MANN, K, ARTIGES, E, PAUS, T, PAUSOVA, Z, LOURDUSAMY, A, SMOLKA, M. N, STRUVE, M, SCHUMANN, G, RIETSCHEL, M, FLOR, H, VOLLSTÄDT-KLEIN, S, STEINER, S, POUSTKA, L, BANASCHEWSKI, T, BARKER, G. J, BÜCHEL, C, CONROD, P. J

“…Genetic variation in a genomic region on chromosome 15q25.1, which encodes the alpha5, alpha3, and beta4 subunits of the cholinergic nicotinic receptor genes,…”
Get full text

Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder by Witt, S H, Juraeva, D, Sticht, C, Strohmaier, J, Meier, S, Treutlein, J, Dukal, H, Frank, J, Lang, M, Deuschle, M, Schulze, T G, Degenhardt, F, Mattheisen, M, Brors, B, Cichon, S, Nöthen, M M, Witt, C C, Rietschel, M

“…Bipolar disorder (BD) is a highly heritable psychiatric disease characterized by recurrent episodes of mania and depression. To identify new BD genes and…”
Get full text

5-HTTLPR/rs25531 polymorphism and neuroticism are linked by resting state functional connectivity of amygdala and fusiform gyrus by Kruschwitz, J. D., Walter, M., Varikuti, D., Jensen, J., Plichta, M. M., Haddad, L., Grimm, O., Mohnke, S., Pöhland, L., Schott, B., Wold, A., Mühleisen, T. W., Heinz, A., Erk, S., Romanczuk-Seiferth, N., Witt, S. H., Nöthen, M. M., Rietschel, M., Meyer-Lindenberg, A., Walter, H.

“…The s/s-genotype of the 5-HTTLPR polymorphism and the personality trait of neuroticism have both been associated with experiences of negative affect, anxiety…”
Get full text

BDNF Val66Met and reward-related brain function in adolescents: Role for early alcohol consumption by Nees, F, Witt, S.H, Dinu-Biringer, R, Lourdusamy, A, Tzschoppe, J, Vollstädt-Klein, S, Millenet, S, Bach, C, Poustka, L, Banaschewski, T, Barker, G.J, Bokde, A.L.W, Bromberg, U, Büchel, C, Conrod, P.J, Frank, J, Frouin, V, Gallinat, J, Garavan, H, Gowland, P, Heinz, A, Ittermann, B, Mann, K, Martinot, J.-L, Paus, T, Pausova, Z, Robbins, T.W, Smolka, M.N, Rietschel, M, Schumann, G, Flor, H

“…Abstract Changes in reward processing have been identified as one important pathogenetic mechanism in alcohol addiction. The nonsynonymous single nucleotide…”
Get full text

A risk marker for alcohol dependence on chromosome 2q35 is related to neuroticism in the general population by Grabe, H J, Mahler, J, Witt, S H, Schulz, A, Appel, K, Spitzer, C, Stender, J, Barnow, S, Freyberger, H J, Teumer, A, Völzke, H, Rietschel, M

Get full text

Exploring the overlap between alopecia areata and major depressive disorder: Epidemiological and genetic perspectives by Foo, J. C., Redler, S., Forstner, A. J., Basmanav, F. B., Pethukova, L., Guo, J., Streit, F., Witt, S. H., Sirignano, L., Zillich, L., Awasthi, S., Ripke, S., Christiano, A. M., Tesch, F., Schmitt, J., Nöthen, M. M., Betz, R. C., Rietschel, M., Frank, J.

“…Background Research suggests that Alopecia areata (AA) and Major Depressive Disorder (MDD) show substantial comorbidity. To date, no study has investigated the…”
Get full text

Prenatal maternal stress is associated with lower cortisol and cortisone levels in the first morning urine of 45-month-old children by Send, T.S., Bardtke, S., Gilles, M., Wolf, I.A.C., Sütterlin, M.W., Wudy, S.A., Wang, R., Laucht, M., Witt, S.H., Rietschel, M., Streit, F., Deuschle, M.

“…•Prospective study on prenatal stress and nocturnal HPA axis activity.•Assessment of cortisol and cortisone in the first morning urine of 45-month-old…”
Get full text

Stress reactivity in preschool-aged children: Evaluation of a social stress paradigm and investigation of the impact of prenatal maternal stress by Send, T.S., Bardtke, S., Gilles, M., Wolf, I.A.C., Sütterlin, M.W., Kirschbaum, C., Laucht, M., Witt, S.H., Rietschel, M., Streit, F., Deuschle, M.

“…•A stress test for preschool-aged children was evaluated (n = 339).•It elicited a cortisol response especially 30 and 40 min after the test.•Prenatal stress…”
Get full text

Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients by Frank, J, Lang, M, Witt, S H, Strohmaier, J, Rujescu, D, Cichon, S, Degenhardt, F, Nöthen, M M, Collier, D A, Ripke, S, Naber, D, Rietschel, M

Get full text

Response to the letter by Esteves et al by Send, T S, Gilles, M, Codd, V, Wolf, I A C, Bardtke, S, Streit, F, Strohmaier, J, Frank, J, Schendel, D, Sütterlin, M W, Denniff, M, Laucht, M, Samani, N J, Deuschle, M, Rietschel, M, Witt, S H

Get full text