Search Results - "Witt, C S"

Post‐Transplant HLA class II Antibodies and High Soluble CD30 Levels are Independently Associated with Poor Kidney Graft Survival by Langan, L. L., Park, L. P., Hughes, T. L., Irish, A., Luxton, G., Witt, C. S., Christiansen, F. T.

“…HLA‐specific antibodies (HSA) and soluble CD30 (sCD30) were measured in 208 renal transplant recipients with functioning grafts at least 1 year after…”
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The genotype of the NK cell receptor, KIR2DL4, influences INFγ secretion by decidual natural killer cells by Goodridge, J.P., Lathbury, L.J., John, E., Charles, A.K., Christiansen, F.T., Witt, C.S.

“…Natural killer (NK) cells are the predominant leukocyte in first trimester decidua and play a role in vascular remodelling through interferon gamma (IFNγ)…”
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Allergic women show reduced T helper type 1 alloresponses to fetal human leucocyte antigen mismatch during pregnancy by Prescott, S.L, Breckler, L.A, Witt, C.S, Smith, L, Dunstan, J.A, Christiansen, F.T

“…Low-level alloreactivity between mother and fetus may provide stimulation for fetal T helper type 1 (Th1) cell immune maturation. This study explored the…”
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Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression by Gaudieri, S, DeSantis, D, McKinnon, E, Moore, C, Nolan, D, Witt, C S, Mallal, S A, Christiansen, F T

“…Variation in the host response to infection by pathogens including HIV-1 may be conferred by polymorphic genetic factors such as HLA and killer…”
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The relevance of natural killer cell human leucocyte antigen epitopes and killer cell immunoglobulin-like receptors in bone marrow transplantation by Witt, C. S., Christiansen, F. T.

“…The discovery that killer cell immunoglobulin‐like receptors (KIR) interact with genetically polymorphic epitopes on class I human leucocyte antigen (HLA)…”
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Menopausal Hormone Therapy and Irregular Endometrial Bleeding: A Potential Role for Uterine Natural Killer Cells? by Hickey, M., Crewe, J., Goodridge, J. P., Witt, C. S., Fraser, I. S., Doherty, D., Christiansen, F. T., Salamonsen, L. A.

“…Context: Irregular bleeding affects many users of combined menopausal hormone therapy (HT) and commonly leads to invasive and expensive investigations to…”
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The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster by Martin, A M, Freitas, E M, Witt, C S, Christiansen, F T

“…Natural killer (NK) immunoglobulin-like receptors (KIRs) are a family of polymorphic receptors which interact with specific motifs on HLA class I molecules and…”
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Population frequencies and putative haplotypes of the killer cell immunoglobulin-like receptor sequences and evidence for recombination by WITT, C. S, DEWING, C, SAYER, D. C, UHRBERG, M, PARHAM, P, CHRISTIANSEN, F. T

“…The killer cell immunoglobulin-like receptors (KIR) are a family of receptors expressed on natural killer (NK) cells and some T cells. Class I HLA molecules on…”
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Maternal KIR repertoire is not associated with recurrent spontaneous abortion by Witt, C.S., Goodridge, J., Gerbase-DeLima, M.G., Daher, S., Christiansen, F.T.

“…BACKGROUND: In view of evidence suggesting an immunological cause of recurrent spontaneous abortions (RSA) and the large number of maternal natural killer (NK)…”
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Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level by Moore, Corey B., John, Mina, James, Ian R., Christiansen, Frank T., Witt, Campbell S., Mallal, Simon A.

“…Antigen-specific T cell immunity is HLA-restricted. Human immunodeficiency virus-type 1 (HIV-1) mutations that allow escape from host immune responses may…”
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Ancestral haplotypes: conserved population MHC haplotypes by Degli-Esposti, M A, Leaver, A L, Christiansen, F T, Witt, C S, Abraham, L J, Dawkins, R L

“…We describe here a number of Caucasoid MHC haplotypes that extend from HLA-B to DR and that have been conserved en bloc. These haplotypes and recombinants…”
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Molecular analysis of HLA class II polymorphisms among different ethnic groups in Israel by Amar, A., Kwon, O.J., Motro, U., Witt, C.S., Bonne-Tamir, B., Gabison, R., Brautbar, C.

“…The Jewish population in Israel comprises of inhabitants of heterogeneous ethnic backgrounds. Genetic studies classify the Israeli Jewish population into two…”
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Matching for MHC haplotypes results in improved survival following unrelated bone marrow transplantation by Tay, G K, Witt, C S, Christiansen, F T, Charron, D, Baker, D, Herrmann, R, Smith, L K, Diepeveen, D, Mallal, S, McCluskey, J

“…Unrelated bone marrow donor-recipient pairs were assessed retrospectively for matching of the HLA-B, -C region (beta-block) and HLA-DR, DQ region (delta block)…”
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The evolution and diversity of TNF block haplotypes in European, Asian and Australian Aboriginal populations by Valente, F P, Tan, C R T, Temple, S E, Phipps, M, Witt, C S, Kaur, G, Gut, I, McGinn, S, Allcock, R J N, Chew, C S N, Price, P

“…The region spanning the tumour necrosis factor (TNF) cluster in the human major histocompatibility complex is implicated in susceptibility to…”
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KIR2DL4 (CD158d) Genotype Influences Expression and Function in NK Cells by Goodridge, Jodie P, Witt, Campbell S, Christiansen, Frank T, Warren, Hilary S

“…The expression and function of the NK cell receptor KIR2DL4 are controversial. Two common alleles of the transmembrane domain of KIR2DL4 exist. The 10A allele…”
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MICA, MICB, and MHC Beta Block Matching in Bone Marrow Transplantation: Relevance to Transplantation Outcome by Kitcharoen, K., Witt, C.S., Romphruk, A.V., Christiansen, F.T., Leelayuwat, C.

“…Genetic testing of the MHC is required for selection of donors for bone marrow transplantation. The outcome of related bone marrow transplantation is usually…”
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Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B by Martin, Annalise M, Kulski, Jerzy K, Gaudieri, Silvana, Witt, Campbell S, Freitas, Elizabeth M, Trowsdale, John, Christiansen, Frank T

“…Members of the killer immunoglobulin (Ig)-like receptor (KIR) gene family are tightly clustered on human chromosome 19q13.4. Despite considerable variation in…”
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Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex : ancestral haplotypes encode particular NK-defined haplotypes by CHRISTIANSEN, F. T, WITT, C. S, CICCONE, E, TOWNEND, D, PENDE, D, VIALE, D, ABRAHAM, L. J, DAWKINS, R. L, MORETTA, L

“…As ancestral haplotypes of the major histocompatibility complex (MHC) appear to define identical MHC haplotypes in unrelated individuals, unrelated individuals…”
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Questions in marrow matching: the implications of ancestral haplotypes for routine practice by Christiansen, F T, Witt, C S, Dawkins, R L

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A role for intestinal T lymphocytes in bronchus mucosal immunity by WALLACE, F. J, CRIPPS, A. W, CLANCY, R. L, HUSBAND, A. J, WITT, C. S

“…Rats immunized by intra-Peyer's patch (IPP) injection with non-typable Haemophilus influenzae (NTHI) have been shown to clear this organism from the…”
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