Search Results - "Witko, Susan"
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Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death
Published in The Journal of clinical investigation (01-01-2020)“…Recent occurrences of filoviruses and the arenavirus Lassa virus (LASV) in overlapping endemic areas of Africa highlight the need for a prophylactic vaccine…”
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Safety and immunogenicity of a highly attenuated rVSVN4CT1-EBOVGP1 Ebola virus vaccine: a randomised, double-blind, placebo-controlled, phase 1 clinical trial
Published in The Lancet infectious diseases (01-04-2020)“…The safety and immunogenicity of a highly attenuated recombinant vesicular stomatitis virus (rVSV) expressing HIV-1 gag (rVSVN4CT1-HIV-1gag1) was shown in…”
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A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile
Published in Microbiology (Society for General Microbiology) (01-07-2013)“…The Clostridium difficile toxins A and B are primarily responsible for symptoms of C. difficile associated disease and are prime targets for vaccine…”
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4
Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates
Published in Journal of virology (01-06-2014)“…In previous work, a prototypic recombinant vesicular stomatitis virus Indiana serotype (rVSIV) vector expressing simian immunodeficiency virus (SIV) gag and…”
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Nonreplicating Vaccines Can Protect African Green Monkeys From the Memphis 37 Strain of Respiratory Syncytial Virus
Published in The Journal of infectious diseases (15-07-2013)“…Background. We evaluated the immunological responses of African green monkeys immunized with multiple F and G protein—based vaccines and assessed protection…”
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Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice
Published in Immunology letters (01-02-2013)“…Highlights ► rVSV-RSV replicon vectors elicit potent neutralizing antibodies in vivo. ► rVSV-RSV vectors elicit primary and memory Th1-biased cellular…”
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An efficient helper-virus-free method for rescue of recombinant paramyxoviruses and rhadoviruses from a cell line suitable for vaccine development
Published in Journal of virological methods (01-07-2006)“…Recovery of recombinant, negative-strand, nonsegmented RNA viruses from a genomic cDNA clone requires a rescue system that promotes de novo assembly of a…”
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Inhibition of measles virus minireplicon-encoded reporter gene expression by V protein
Published in Virology (New York, N.Y.) (25-04-2006)“…Measles virus V protein is a Cys-rich polypeptide that is dispensable for virus propagation in continuous cell lines, but necessary for efficient viral…”
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Role of V protein RNA binding in inhibition of measles virus minigenome replication
Published in Virology (New York, N.Y.) (25-04-2006)“…Measles virus V protein represses genome replication through a poorly understood mechanism, which led us to investigate whether V protein might be an…”
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Recombinant Vesicular Stomatitis Virus Vectors Expressing Herpes Simplex Virus Type 2 gD Elicit Robust CD4+ Th1 Immune Responses and Are Protective in Mouse and Guinea Pig Models of Vaginal Challenge
Published in Journal of Virology (01-05-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Refined methods for propagating vesicular stomatitis virus vectors that are defective for G protein expression
Published in Journal of virological methods (01-03-2010)“…Propagation-defective vesicular stomatitis virus (VSV) vectors that encode a truncated G protein (VSV-Gstem) or lack the G gene entirely (VSV-ΔG) are…”
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Immunogenicity of co-administered recombinant VSV vectors expressing GM-CSF and HIV-1 Gag in mice (47.25)
Published in The Journal of immunology (1950) (01-04-2007)“…Abstract Highly attenuated recombinant vesicular stomatitis virus (rVSV) vectors expressing HIV-1 Gag have been shown to be immunogenic in preclinical animal…”
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Recombinant Vesicular Stomatitis Virus Vectors Expressing Herpes Simplex Virus Type 2 gD Elicit Robust CD4 super(+) Th1 Immune Responses and Are Protective in Mouse and Guinea Pig Models of Vaginal Challenge
Published in Journal of virology (01-05-2006)“…Recombinant vesicular stomatitis virus (rVSV) vectors offer an attractive approach for the induction of robust cellular and humoral immune responses directed…”
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14
The relationship of identity formation to maternal sensitivity in adolescents
Published 01-01-1989“…This dissertation was designed to test the prediction that level of identity formation can predict maternal sensitivity in adolescent mothers with their…”
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Dissertation