Search Results - "Witjaksono, Clea"

Radiolysis of myoglobin concentrated gels by protons: specific changes in secondary structure and production of carbon monoxide by Ludwig, Nicolas, Galindo, Catherine, Witjaksono, Clea, Danvin, Antoine, Peaupardin, Philippe, Muller, Dominique, Kusumoto, Tamon, Kodaira, Satoshi, Barillon, Rémi, Raffy, Quentin

“…While particle therapy has been used for decades for cancer treatment, there is still a lack of information on the molecular mechanisms of biomolecules…”
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Cover Feature: Irreversible Inhibition of IspG, a Target for the Development of New Antimicrobials, by a 2‐Vinyl Analogue of its MEcPP Substrate (Chem. Eur. J. 30/2022) by Herrscher, Vivien, Witjaksono, Clea, Buchotte, Marie, Ferret, Claire, Massicot, Fabien, Vasse, Jean‐Luc, Borel, Franck, Behr, Jean‐Bernard, Seemann, Myriam

“…The rational design of a substrate analogue has afforded the first irreversible inhibitor of an IspG enzyme, a target for the development of new drugs to fight…”
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Carbohydrate-Templated Syntheses of Trifluoromethyl-Substituted MEP Analogues for the Study of the Methylerythritol Phosphate Pathway by Simonet, Basile, Herrscher, Vivien, Witjaksono, Clea, Chaignon, Philippe, Massicot, Fabien, Vasse, Jean-Luc, Seemann, Myriam, Behr, Jean-Bernard

“…Trifluoromethyl analogues of methylerythritol phosphate (MEP) and 2-C-methyl-erythritol 2,4-cyclodiphosphate (MEcPP), natural substrates of key enzymes from…”
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Irreversible Inhibition of IspG, a Target for the Development of New Antimicrobials, by a 2‐Vinyl Analogue of its MEcPP Substrate by Herrscher, Vivien, Witjaksono, Clea, Buchotte, Marie, Ferret, Claire, Massicot, Fabien, Vasse, Jean‐Luc, Borel, Franck, Behr, Jean‐Bernard, Seemann, Myriam

“…IspG (also called GcpE) is an oxygen‐sensitive [4Fe‐4S] enzyme catalyzing the penultimate step of the methylerythritol phosphate (MEP) pathway, a validated…”
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