Search Results - "Withopf, B"
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of BI 1356, an Inhibitor of Dipeptidyl Peptidase 4, in Healthy Male Volunteers
Published in Journal of clinical pharmacology (01-10-2008)“…This randomized, double‐blind, parallel, placebo‐controlled, single rising‐dose study investigated the safety, tolerability, pharmacokinetic, and…”
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Evaluation of the potential for steady-state pharmacokinetic and pharmacodynamic interactions between the DPP-4 inhibitor linagliptin and metformin in healthy subjects
Published in Current medical research and opinion (01-08-2009)“…ABSTRACT Objective: Linagliptin (BI 1356) is a novel, orally available inhibitor of dipeptidyl peptidase-4 (DPP-4). Linagliptin improves glycaemic control in…”
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3
Effect of linagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers
Published in International journal of clinical pharmacology and therapeutics (01-05-2011)“…To investigate the effect of the estimated highest therapeutic dose of linagliptin (5 mg) on the pharmacokinetics and pharmacodynamics of warfarin, a CYP2C9…”
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4
Sensitive and Selective Screening for 6‘-O-Malonylated Glucoconjugates in Plants
Published in Journal of agricultural and food chemistry (01-03-1997)“…Using synthesized reference compounds a screening for benzyl, 2-phenylethyl, geranyl, citronellyl, and 2,5-dimethyl-4-hydroxy-3(2H)-furanone 6‘-O-malonyl…”
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5
Efficient and enantioselective catalysis by the semisynthetic peroxidase seleno-subtilisin
Published in Tetrahedron: asymmetry (27-03-1997)“…By selective modification of serine 221 in the active site, the preceding protease subtilisin carlsberg gained peroxidase activity which was subsequently…”
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Absolute Configuration and Conformation of 1,3-Dioxanes from Cider
Published in Journal of agricultural and food chemistry (01-08-1997)“…In extracts obtained by liquid−liquid extraction from French cider (2S,4R)- and (2R,4R)-2-methyl-4-pentyl-1,3-dioxane, 1a and 1b as well as (2S,4R)- and…”
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7
Evaluation of the potential for steady-state pharmacokinetic and pharmacodynamic interactions between the DPP-4 inhibitor linagliptin and metformin in healthy subjects
Published in Current Medical Research and Opinion (01-08-2009)“…Objective: Linagliptin (BI 1356) is a novel, orally available inhibitor of dipeptidyl peptidase-4 (DPP-4). Linagliptin improves glycaemic control in type 2…”
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