Search Results - "Witek, Przemyslaw"
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Pasireotide—a novel somatostatin receptor ligand after 20 years of use
Published in Reviews in endocrine & metabolic disorders (01-06-2022)“…Pasireotide, a novel multireceptor-targeted somatostatin receptor ligand (SRL) is characterized by a higher affinity to somatostatin receptor type 5 than type…”
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Case report: A challenging case of severe Cushing's syndrome in the course of metastatic thymic neuroendocrine carcinoma with a synchronous adrenal tumor
Published in Frontiers in endocrinology (Lausanne) (14-06-2024)“…Ectopic ACTH syndrome (EAS) remains one of the most demanding diagnostic and therapeutic challenges for endocrinologists. Thymic neuroendocrine tumors account…”
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3
Prolactinomas: Prognostic Factors of Early Remission After Transsphenoidal Surgery
Published in Frontiers in endocrinology (Lausanne) (07-07-2020)“…Most patients with prolactinomas receive pharmacological treatment only, resulting in limited research on the predictors of successful prolactinoma surgery. In…”
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Medical treatment of Cushing's disease with concurrent diabetes mellitus
Published in Frontiers in endocrinology (Lausanne) (17-04-2023)“…Cushing's disease (CD) is a severe endocrine disorder characterized by chronic hypercortisolaemia secondary to an overproduction of adrenocorticotropic hormone…”
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Prolactin-secreting pituitary adenomas: male-specific differences in pathogenesis, clinical presentation and treatment
Published in Frontiers in endocrinology (Lausanne) (2024)“…Prolactinomas (PRLomas) constitute approximately half of all pituitary adenomas and approximately one-fifth of them are diagnosed in males. The clinical…”
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Managing pasireotide-associated hyperglycemia: a randomized, open-label, Phase IV study
Published in Pituitary (01-12-2021)“…Purpose Pasireotide is an effective treatment for acromegaly and Cushing’s disease, although treatment-emergent hyperglycemia can occur. The objective of this…”
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Editorial: Insights Into Acromegaly Complications
Published in Frontiers in endocrinology (Lausanne) (27-06-2022)Get full text
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Critical illness-related corticosteroid insufficiency (CIRCI) - an overview of pathogenesis, clinical presentation and management
Published in Frontiers in endocrinology (Lausanne) (06-11-2024)“…According to the Society of Critical Care Medicine, critical illness-related corticosteroid insufficiency (CIRCI) characterizes hypothalamic-adrenal axis…”
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1841-PUB: Diabetes as a Risk Factor of Death in Hospitalized COVID-19 Patients—An Analysis of a National Hospitalization Database from Poland, 2020
Published in Diabetes (New York, N.Y.) (23-06-2023)“…Introduction: Diabetes has been linked with poor clinical prognosis of hospitalized COVID-19 patients. In this nationwide database retrospective study we…”
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1522-P: High Incidence of Hospital-Onset Clostridium Difficile Infection in Diabetic Foot Syndrome Patients: Data from a Single Tertiary Diabetes Care Clinic in Poland
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Diabetic Foot Syndrome (DFS) commonly occurs with infected ulceration and is associated with a high rate of amputation and excessive mortality. Antibiotic…”
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Risk of macrosomia remains glucose-dependent in a cohort of women with pregestational type 1 diabetes and good glycemic control
Published in Endocrine (01-02-2017)“…Macrosomia risk remains high in type 1 diabetes (T1DM) complicated pregnancies. A linear relationship between macrosomia risk and glycated hemoglobin A 1c (HbA…”
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657-P: Frequency Scanning Correlates Not Only with Glycemic Indices but Also with Fear of Hypoglycemia in Type 1 Diabetes Patients Using is-CGMS
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Frequency scanning with intermittently scanned CGMS (is-CGMS) is associated with glycemic indices. No data is available for its correlation with fear of…”
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The Effect of 6 Months' Treatment With Pasireotide LAR on Glucose Metabolism in Patients With Resistant Acromegaly in Real-World Clinical Settings
Published in Frontiers in endocrinology (Lausanne) (10-03-2021)“…The aim of the study was to evaluate glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels and the need for antidiabetic medical treatment, in…”
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14
Use of late-night salivary cortisol to monitor response to medical treatment in Cushing’s disease
Published in European journal of endocrinology (01-02-2020)“…Objective Monitoring of patients with Cushing’s disease on cortisol-lowering drugs is usually performed with urinary free cortisol (UFC). Late-night salivary…”
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15
Left Heart Dysfunction in Acromegaly Revealed by Novel Echocardiographic Methods
Published in Frontiers in endocrinology (Lausanne) (24-06-2020)“…Background: Acromegaly is a rare disease that requires modern treatment to decrease the risk of mortality, mainly from vascular diseases. Identifying…”
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Cushing's Disease: Long-Term Effectiveness and Safety of Osilodrostat in a Polish Group of Patients with Persistent Hypercortisolemia in the Experience of a Single Center
Published in Biomedicines (01-12-2023)“…Osilodrostat is a potent oral steroidogenesis inhibitor that has emerged as the new medical agent for patients with Cushing's disease (CD) requiring long-term…”
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Assessment of the spectrum of depression and bipolarity in patients with type 1 diabetes
Published in Diabetes/metabolism research and reviews (01-01-2023)“…Aims The aim of the study was to check the prevalence of unipolarity (depression), bipolarity, as well as the quality of sleep and temperament traits in…”
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Increased Thoracic Fluid as the Most Distinctive Cardiovascular Hemodynamic Alteration in Men with Prolactinoma
Published in Nutrients (17-12-2022)“…Hyperprolactinemia in males with prolactin-secreting adenomas, or prolactinomas, may be associated with endothelial dysfunction and co-existing cardiovascular…”
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Predictive factors and the management of hyperglycemia in patients with acromegaly and Cushing's disease receiving pasireotide treatment: post hoc analyses from the SOM230B2219 study
Published in Frontiers in endocrinology (Lausanne) (21-03-2024)“…Pasireotide, a somatostatin receptor ligand, is approved for treating acromegaly and Cushing's disease (CD). Hyperglycemia during treatment can occur because…”
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Osilodrostat — an emerging drug for the medical management of Cushing’s disease
Published in Endokrynologia polska (01-01-2022)“…Cushing’s disease (CD) is a rare endocrine disorder characterized by the overproduction of adrenocorticotropic hormone (ACTH) by pituitary adenoma followed by…”
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