Search Results - "Witek, Gabriela M."
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Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma
Published in Nature communications (05-05-2023)“…Activating point mutations in Anaplastic Lymphoma Kinase (ALK ) have positioned ALK as the only mutated oncogene tractable for targeted therapy in…”
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Comprehensive pharmacological profiling of neurofibromatosis cell lines
Published in American journal of cancer research (01-01-2017)“…Patients with Neurofibromatosis type 1 (NF1) and Neurofibromatosis type 2 (NF2) are predisposed to tumors of the nervous system. NF1 patients predominantly…”
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Abstract 1633: Chemical proteomics identifies druggable proteins in ALK-driven neuroblastomas
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…The discovery of mutations in the ALK oncogene as the genetic etiology of familial neuroblastoma (NB) and as somatically acquired in 14% of patients with the…”
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Journal Article