Search Results - "Witcher, J. W."

Pharmacokinetics, Safety, and Tolerability of Atomoxetine and Effect of CYP2D610/10 Genotype in Healthy Japanese Men by Matsui, A., Azuma, J., Witcher, J. W., Long, A. J., Sauer, J.-M., Smith, B. P., DeSante, K. A., Read, H. A., Takahashi, M., Nakano, M.

“…Atomoxetine is a cytochrome P4502D6 (CYP2D6) substrate. The reduced-activity CYP2D6*10 allele is particularly prevalent in the Japanese population and may…”
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Pharmacokinetics of 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)uracil in woodchucks by WITCHER, J. W, BOUDINOT, F. D, BALDWIN, B. H, ASCENZI, M. A, TENNANT, B. C, DU, J. F, CHU, C. K

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Applications and simulations of a discontinuous oral absorption pharmacokinetic model by WITCHER, J. W, BOUDINOT, F. D

“…To illustrate the application of a discontinuous oral absorption model to cimetidine and ranitidine plasma concentration versus time data to demonstrate the…”
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Clinical pharmacokinetics of atomoxetine by SAUER, John-Michael, RING, Barbara J, WITCHER, Jennifer W

“…Atomoxetine (Strattera, a potent and selective inhibitor of the presynaptic norepinephrine transporter, is used clinically for the treatment of…”
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Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism by SAUER, John-Michael, PONSLER, G. Douglas, MATTIUZ, Edward L, LONG, Amanda J, WITCHER, Jennifer W, THOMASSON, Holly R, DESANTE, Karl A

“…The role of the polymorphic cytochrome P450 2D6 (CYP2D6) in the pharmacokinetics of atomoxetine hydrochloride [(−)- N…”
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Atomoxetine pharmacokinetics in children and adolescents with attention deficit hyperactivity disorder by Witcher, Jennifer W, Long, Amanda, Smith, Brian, Sauer, John-Michael, Heilgenstein, John, Wilens, Timothy, Spencer, Thomas, Biederman, Joseph

“…Atomoxetine is indicated for the treatment of attention deficit hyperactivity disorder in children, adolescents, and adults. This study was conducted, in part,…”
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Effect of Potent CYP2D6 Inhibition by Paroxetine on Atomoxetine Pharmacokinetics by Belle, Donna J., Ernest, C. Steven, Sauer, John-Michael, Smith, Brian P., Thomasson, Holly R., Witcher, Jennifer W.

“…The purpose of this study was to characterize the effect of potent CYP2D6 inhibition by paroxetine on atomoxetine disposition in extensive metabolizers. This…”
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Atomoxetine hydrochloride: clinical drug-drug interaction prediction and outcome by Sauer, John-Michael, Long, Amanda J, Ring, Barbara, Gillespie, Jennifer S, Sanburn, Nathan P, DeSante, Karl A, Petullo, David, VandenBranden, Mark R, Jensen, Charles B, Wrighton, Steven A, Smith, Brian P, Read, Holly A, Witcher, Jennifer W

“…In the studies reported here, the ability of atomoxetine hydrochloride (Strattera) to inhibit or induce the metabolic capabilities of selected human isoforms…”
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A new automatic peritoneal dialyser by Parker, A S, Witcher, J W, Barrett, R H, Mackenzie, J C, Iles, R N, Shaw, A F

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