Search Results - "Wissniowski, Till"

The Crosstalk of miRNA and Oxidative Stress in the Liver: From Physiology to Pathology and Clinical Implications by Klieser, Eckhard, Mayr, Christian, Kiesslich, Tobias, Wissniowski, Till, Fazio, Pietro Di, Neureiter, Daniel, Ocker, Matthias

“…The liver is the central metabolic organ of mammals. In humans, most diseases of the liver are primarily caused by an unhealthy lifestyle-high fat diet, drug…”
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Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases by Hansler, Johannes, Wissniowski, Thaddaus-Till, Schuppan, Detlef, Witte, Astrid, Bernatik, Thomas, Hahn, Eckhart-Georg, Strobel, Deike

“…AIM： To assess if a specific cytotoxic T cell response can be induced in patients with malignant liver tumors treated with radio-frequency ablation （RFA）…”
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Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation by Behm, Barbara, Di Fazio, Pietro, Michl, Patrick, Neureiter, Daniel, Kemmerling, Ralf, Hahn, Eckhart Georg, Strobel, Deike, Gress, Thomas, Schuppan, Detlef, Wissniowski, Thaddaeus Till

“…Radiofrequency ablation (RFA), a palliative therapeutic option for solid hepatic tumours, stimulates localised and systemic antitumour cytotoxic T cells. We…”
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Activation of tumor-specific T lymphocytes by radio-frequency ablation of the VX2 hepatoma in rabbits by WISSNIOWSKI, Thädaus Till, HÜNSLER, Johannes, NEUREITER, Daniel, FRIESER, Markus, SCHABER, Stefan, ESSLINGER, Birgit, VOLL, Reinhard, STROBEL, Deike, HAHN, Eckhart G, SCHUPPAN, Detlef

“…Radio-frequency ablation (RFA) is used as a minimally invasive treatment for inoperable hepatic tumors. Immunological reactions secondary to RFA may play a…”
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The pan-deacetylase inhibitor panobinostat inhibits growth of hepatocellular carcinoma models by alternative pathways of apoptosis by Di Fazio, Pietro, Schneider-Stock, Regine, Neureiter, Daniel, Okamoto, Kinya, Wissniowski, Till, Gahr, Susanne, Quint, Karl, Meissnitzer, Matthias, Alinger, Beate, Montalbano, Roberta, Sass, Gabriele, Hohenstein, Bernd, Hahn, Eckhart G, Ocker, Matthias

“…Inhibition of deacetylases represents a new treatment option for human cancer diseases. We applied the novel and potent pan-deacetylase inhibitor panobinostat…”
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Combination of the deacetylase inhibitor panobinostat and the multi-kinase inhibitor sorafenib for the treatment of metastatic hepatocellular carcinoma - review of the underlying molecular mechanisms and first case report by Gahr, Susanne, Wissniowski, Till, Zopf, Steffen, Strobel, Deike, Pustowka, Anette, Ocker, Matthias

“…Advanced hepatocellular carcinoma still represents an unmet medical need that has only a limited overall survival despite the introduction of the multi-kinase…”
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Sustained treatment response of metastatic hepatocellular carcinoma with bevacizumab and sorafenib by Wich, Christina, Agaimy, Abbas, Strobel, Deike, Wissniowski, Thaddäus Till, Hartmann, Arndt, Ocker, Matthias

“…The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently…”
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The histone-deacetylase inhibitor MS-275 and the CDK-inhibitor CYC-202 promote anti-tumor effects in hepatoma cell lines by GAHR, Susanne, PETER, Gisela, WISSNIOWSKI, Thadäus Till, HAHN, Eckhart G, HEROLD, Christoph, OCKER, Matthias

“…Effective therapies for advanced stages of hepatocellular carcinoma (HCC) have yet to be developed. We investigated how far a combination of the HDAC inhibitor…”
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Cannabinoid receptor type I modulates alcohol-induced liver fibrosis by Patsenker, Eleonora, Stoll, Matthias, Millonig, Gunda, Agaimy, Abbas, Wissniowski, Till, Schneider, Vreni, Mueller, Sebastian, Brenneisen, Rudolf, Seitz, Helmut K, Ocker, Matthias, Stickel, Felix

“…The cannabinoid system (CS) is implicated in the regulation of hepatic fibrosis, steatosis and inflammation, with cannabinoid receptors 1 and 2 (CB1 and CB2)…”
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The pan-deacetylase inhibitor panobinostat affects angiogenesis in hepatocellular carcinoma models via modulation of CTGF expression by GAHR, SUSANNE, MAYR, CHRISTIAN, KIESSLICH, TOBIAS, ILLIG, ROMANA, NEUREITER, DANIEL, ALINGER, BEATE, GANSLMAYER, MARION, WISSNIOWSKI, TILL, DI FAZIO, PIETRO, MONTALBANO, ROBERTA, FICKER, JOACHIM H, OCKER, MATTHIAS, QUINT, KARL

“…Post-translational modifications of chromatin components are significantly involved in the regulation of tumor suppressor gene and oncogene expression…”
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Role of cannabinoid receptors and RAGE in inflammatory bowel disease by Stintzing, Sebastian, Wissniowski, Till Th, Lohwasser, Christina, Alinger, Beate, Neureiter, Daniel, Ocker, Matthias

“…The endocannabinoid system is involved in many inflammatory diseases, such as Crohn's disease (CD) and ulcerative colitis (UC). The distribution and expression…”
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Cellular plasticity of trans- and dedifferentiation markers in human hepatoma cells in vitro and in vivo by JABARI, Samir, MEISSNITZER, Matthias, QUINT, Karl, GAHR, Susanne, WISSNIOWSKI, Till, HAHN, Eckhart G, NEUREITER, Daniel, OCKER, Matthias

“…Tumor cells have the capability to trans- and to dedifferentiate, for example by reactivating embryonic development genes and stem cell characteristics. The…”
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The dual EGF/VEGF receptor tyrosine kinase inhibitor AEE788 inhibits growth of human hepatocellular carcinoma xenografts in nude mice by OKAMOTO, Kinya, NEUREITER, Daniel, KAUFMANN, Bernhard, SCHLÖSSER, Axel, HAUS, Ulrike, HAHN, Eckhart G, HEROLD, Christoph, OCKER, Matthias, ALINGER, Beate, MEISSNITZER, Matthias, SASS, Gabriele, SCHMITZ, Volker, DI FAZIO, Pietro, WISSNIOWSKI, Till, GAHR, Susanne, HOHENSTEIN, Bernd

“…We investigated the effect of AEE788, a novel dual receptor tyrosine kinase inhibitor of the EGF and the VEGF receptor, for treatment of human HCC cell lines…”
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German Real-World Experience of Patients with Diverse Features of Acute Intermittent Porphyria Treated with Givosiran by Kubisch, Ilja, Wohmann, Nils, Wissniowski, Thaddäus Till, Stauch, Thomas, Oettel, Lucienne, Diehl-Wiesenecker, Eva, Somasundaram, Rajan, Stölzel, Ulrich

“…Background/Objectives: Acute intermittent porphyria (AIP) is a metabolic disease characterised by neurovisceral crises with episodes of acute abdominal pain…”
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Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells by Montalbano, Roberta, Honrath, Birgit, Wissniowski, Thaddeus Till, Elxnat, Moritz, Roth, Silvia, Ocker, Matthias, Quint, Karl, Churin, Yuri, Roederfeld, Martin, Schroeder, Dirk, Glebe, Dieter, Roeb, Elke, Di Fazio, Pietro

“…HBV represents the most common chronic viral infection and major cause of hepatocellular carcinoma (HCC), although its exact role in liver tumorigenesis is…”
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Mucin production determines sensitivity to bortezomib and gemcitabine in pancreatic cancer cells by WISSNIOWSKI, Thaddäus Till, MEISTER, Silke, HAHN, Eckhart G, KALDEN, Joachim R, VOLL, Reinhard, OCKER, Matthias

“…The prognosis of pancreatic cancer remains disappointing due to a high intrinsic resistance against chemotherapeutic agents. Standard gemcitabine therapies…”
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The Pan-Deacetylase Inhibitor Panobinostat Inhibits Growth of Hepatocellular Carcinoma Models by Alternative Pathways of Apoptosis by Di Fazio, Pietro, Schneider-Stock, Regine, Neureiter, Daniel, Okamoto, Kinya, Wissniowski, Till, Gahr, Susanne, Quint, Karl, Meissnitzer, Matthias, Alinger, Beate, Montalbano, Roberta, Sass, Gabriele, Hohenstein, Bernd, Hahn, Eckhart G., Ocker, Matthias

“…Inhibition of deacetylases represents a new treatment option for human cancer diseases. We applied the novel and potent pan-deacetylase inhibitor panobinostat…”
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Pulsed radiofrequency ablation using perfused needle applicators in an in vitro trial on bovine liver by Frieser, Markus, Strobel, Deike, Schaber, Stefan, Wissniowski, Thaddaeus Till, Bernatik, Thomas, Adis, Steffen, Hahn, Eckhart Georg, Hänsler, Johannes Marcus

“…Intermittent energy application seems to have positive effects in achieving necrotic zones. We analyzed different pulse periods (PPs) to optimize this method…”
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38 Activation of tumor specific T lymphocytes after radio-frequency ablation in patients with liver metastases by Wissniowski, Thaddaeus Till H., Haensler, Johannes, Bernatik, Thomas, Schuppan, Detlef, Hahn, E.G., Strobel, Deike

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