Search Results - "Wisner, Alexander"

Methamphetamine-induced lethal toxicity in zebrafish larvae by Chen, Yu, Wisner, Alexander S., Schiefer, Isaac T., Williams, Frederick E., Hall, F. Scott

“…Rationale The use of novel psychoactive substances has been steadily increasing in recent years. Given the rapid emergence of new substances and their…”
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Chronotropic and vasoactive properties of the gut bacterial short-chain fatty acids in larval zebrafish by Sree Kumar, Hemaa, Wisner, Alexander S, Schiefer, Isaac T, Alviter Plata, Adriana, Zubcevic, Jasenka

“…Short-chain fatty acids (SCFAs) produced by the gut bacteria have been associated with cardiovascular dysfunction in humans and rodents. However, studies…”
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Small fish, big discoveries: zebrafish shed light on microbial biomarkers for neuro-immune-cardiovascular health by Sree Kumar, Hemaa, Wisner, Alexander S, Refsnider, Jeanine M, Martyniuk, Christopher J, Zubcevic, Jasenka

“…Zebrafish ( ) have emerged as a powerful model to study the gut microbiome in the context of human conditions, including hypertension, cardiovascular disease,…”
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Zebrafish as a Model for Multiple Sclerosis by Maktabi, Briana, Collins, Abigail, Safee, Raihaanah, Bouyer, Jada, Wisner, Alexander S, Williams, Frederick E, Schiefer, Isaac T

“…Zebrafish have become a key model organism in neuroscience research because of their unique advantages. Their genetic, anatomical, and physiological…”
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Synthetic Psychoactive Cathinones (SPCs): Predicting Toxicity using In Vitro and In Vivo Models by Dressel, Sydnee, Kountz, Logan, Latherow, Faith, Wisner, Alexander, Hall, Frank, Schiefer, Isaac, Widman, Corey, Williams, Frederick

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Alcohol consumption impairs the ependymal cilia motility in the brain ventricles by Omran, Alzahra J. Al, Saternos, Hannah C., Althobaiti, Yusuf S., Wisner, Alexander, Sari, Youssef, Nauli, Surya M., AbouAlaiwi, Wissam A.

“…Ependymal cilia protrude into the central canal of the brain ventricles and spinal cord to circulate the cerebral spinal fluid (CSF). Ependymal cilia…”
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HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies by Amawi, Haneen, Hussein, Noor A, Karthikeyan, Chandrabose, Manivannan, Elangovan, Wisner, Alexander, Williams, Frederick E, Samuel, Temesgen, Trivedi, Piyush, Ashby, Jr, Charles R, Tiwari, Amit K

“…This study was designed to determine the mechanisms by which the novel silybin derivative, (E)-3-(3-(benzyloxy) phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one ( or…”
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Differential Toxicity of mDia Formin-Directed Functional Agonists and Antagonists in Developing Zebrafish by LeCorgne, Hunter, Tudosie, Andrew M, Lavik, Kari, Su, Robin, Becker, Kathryn N, Moore, Sara, Walia, Yashna, Wisner, Alexander, Koehler, Daniel, Alberts, Arthur S, Williams, Frederick E, Eisenmann, Kathryn M

“…The mammalian Diaphanous-related (mDia) formins are cytoskeletal regulators that assemble and, in some cases, bundle filamentous actin (F-actin), as well as…”
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Abstract 088: Modulatory Effects Of The Gut Microbiota-derived Short Chain Fatty Acids On Heart Rate And Vascular Tone In Larval Zebrafish by Sree Kumar, Hemaa, Wisner, Alexander, Schiefer, Isaac T, Zubcevic, Jasenka

“…Abstract only Introduction: Short chain fatty acids (SCFAs), such as acetic, propionic, and butyric acid, areproduced by fermentation of dietary fibers by the…”
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Abstract P061: Effect Of Short Chain Fatty Acid Butyrate On Cardiovascular Parameters In The Zebrafish Larvae by Sree Kumar, Hemaa, Wisner, Alexander S, Schiefer, Isaac T, Zubcevic, Jasenka

“…Abstract only Introduction: Short-chain fatty acids (SCFAs) such as butyrate are produced by microbial fermentation of dietary fiber in the gut. While the…”
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Synthetic Psychoactive Cathinones (SPCs): Predicting Toxicity using In Vitro and In Vivo Models by Sydnee Dressel, Logan Kountz, Faith Latherow, Alexander Wisner, Frank Hall, Isaac Schiefer, Corey Widman, Frederick Williams

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Development of a Zebrafish Platform for Assessing Toxicity and Lethality of Emerging Psychoactive Substances and Its Use for Discovery of Novel Therapeutic Targets by Wisner, Alexander S

“…Novel synthetic psychostimulants (i.e., `bath salts') have begun to replace common drugs of abuse like methamphetamine (MA) and…”
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Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish by Tackie-Yarboi, Ethel, Wisner, Alexander, Horton, Austin, Chau, Tue Q. T, Reigle, James, Funk, Adam J, McCullumsmith, Robert E, Hall, Frank S, Williams, Frederick E, Schiefer, Isaac T

“…Photoaffinity labeling (PAL) remains one of the most widely utilized methods of determining protein targets of drugs. Although useful, the scope of this…”
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The Evaluation of Neurotrophic Factor's Ability to Prevent Induced Cell Death in a PC12 Cell Based Huntington's Disease Model by Wisner, Alexander S

“…Huntington's disease (HD) is caused by a genetic mutation of the IT-15 gene resulting in the expansion of the trinucleotide CAG in the huntingtin protein…”
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