Search Results - "Wisman, G. Bea A."

Nationwide prevalence of human papillomavirus infection and viral genotype distribution in 37 cities in China by Wang, Rong, Guo, Xiao-Lei, Wisman, G Bea A, Schuuring, Ed, Wang, Wen-Feng, Zeng, Zheng-Yu, Zhu, Hong, Wu, Shang-Wei

“…Type-specific high-risk HPV (hrHPV) infection is related to cervical carcinogenesis. The prevalence of hrHPV infection varies geographically, which might…”
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Genome-wide DNA methylation in relation to ARID1A deficiency in ovarian clear cell carcinoma by Li, Shang, Meersma, Gert Jan, Kupryjanczyk, Jolanta, de Jong, Steven, Wisman, G Bea A

“…The poor chemo-response and high DNA methylation of ovarian clear cell carcinoma (OCCC) have attracted extensive attentions. Recently, we revealed the…”
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ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors by Berns, Katrien, Caumanns, Joseph J., Hijmans, E. Marielle, Gennissen, Annemiek M. C., Severson, Tesa M., Evers, Bastiaan, Wisman, G. Bea A., Jan Meersma, Gert, Lieftink, Cor, Beijersbergen, Roderick L., Itamochi, Hiroaki, van der Zee, Ate G. J., de Jong, Steven, Bernards, René

“…Current treatment for advanced stage ovarian clear cell cancer is severely hampered by a lack of effective systemic therapy options, leading to a poor outlook…”
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Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer by Tomar, Tushar, Alkema, Nicolette G, Schreuder, Leroy, Meersma, Gert Jan, de Meyer, Tim, van Criekinge, Wim, Klip, Harry G, Fiegl, Heidi, van Nieuwenhuysen, Els, Vergote, Ignace, Widschwendter, Martin, Schuuring, Ed, van der Zee, Ate G J, de Jong, Steven, Wisman, G Bea A

“…Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of patients will relapse with…”
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Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene by Mittempergher, Lorenza, Piskorz, Anna M, Bosma, Astrid J, Michaut, Magali, Wisman, G Bea A, Kluin, Roelof J C, Nieuwland, Marja, Brugman, Wim, van der Ven, Kevin J W, Marass, Francesco, Morris, James, Rosenfeld, Nitzan, Jimenez-Linan, Mercedes, de Jong, Steven, van der Zee, Ate G J, Brenton, James D, Bernards, René

“…High-grade serous ovarian carcinoma (HGSOC) remains the deadliest form of epithelial ovarian cancer and despite major efforts little improvement in overall…”
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Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways by Tomar, Tushar, de Jong, Steven, Alkema, Nicolette G, Hoekman, Rieks L, Meersma, Gert Jan, Klip, Harry G, van der Zee, Ate Gj, Wisman, G Bea A

“…In high-grade serous ovarian cancer (HGSOC), intrinsic and/or acquired resistance against platinum-containing chemotherapy is a major obstacle for successful…”
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Genome-wide promoter analysis uncovers portions of the cancer methylome by Hoque, Mohammad Obaidul, Kim, Myoung Sook, Ostrow, Kimberly Laskie, Liu, Junwei, Wisman, G Bea A, Park, Hannah Lui, Poeta, Maria Luana, Jeronimo, Carmen, Henrique, Rui, Lendvai, Agnes, Schuuring, Ed, Begum, Shahnaz, Rosenbaum, Eli, Ongenaert, Maté, Yamashita, Keishi, Califano, Joseph, Westra, William, van der Zee, Ate G J, Van Criekinge, Wim, Sidransky, David

“…DNA methylation has a role in mediating epigenetic silencing of CpG island genes in cancer and other diseases. Identification of all gene promoters methylated…”
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Expression of Epidermal Growth Factor Receptor (EGFR) and Activated EGFR Predict Poor Response to (Chemo)radiation and Survival in Cervical Cancer by NOORDHUIS, Maartje G, EIJSINK, Jasper J. H, WISMAN, G. Bea A, SCHUURING, Ed, VAN DER ZEE, Ate G. J, TEN HOOR, Klaske A, ROOSSINK, Frank, HOLLEMA, Harry, ARTS, Henriëtte J. G, PRAS, Elisabeth, MADURO, John H, REYNERS, Anna K. L, DE BOCK, Geertruida H

“…Purpose: Activation of the epidermal growth factor receptor (EGFR) signaling pathway has been reported to induce resistance to (chemo)radiation in cancers,…”
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Identification and validation of WISP1 as an epigenetic regulator of metastasis in oral squamous cell carcinoma by Clausen, Martijn J. A. M., Melchers, Lieuwe J., Mastik, Mirjam F., Slagter-Menkema, Lorian, Groen, Harry J. M., van der Laan, Bernard F. A. M., van Criekinge, Wim, de Meyer, Tim, Denil, Simon, Wisman, G. Bea A., Roodenburg, Jan L. N., Schuuring, Ed

“…Lymph node (LN) metastasis is the most important prognostic factor in oral squamous cell carcinoma (OSCC) patients. However, in approximately one third of OSCC…”
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Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer by Fedoseienko, Alina, Wieringa, Hylke W, Wisman, G Bea A, Duiker, Evelien, Reyners, Anna K L, Hofker, Marten H, van der Zee, Ate G J, van de Sluis, Bart, van Vugt, Marcel A T M

“…Copper metabolism MURR1 domain 1 (COMMD1) protein is a multifunctional protein, and its expression has been correlated with patients' survival in different…”
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Prognostic Cell Biological Markers in Cervical Cancer Patients Primarily Treated With (Chemo)radiation: A Systematic Review by Noordhuis, Maartje G., B.Sc, Eijsink, Jasper J.H., M.D, Roossink, Frank, M.Sc, de Graeff, Pauline, M.D., Ph.D, Pras, Elisabeth, M.D., Ph.D, Schuuring, Ed, Ph.D, Wisman, G. Bea A., Ph.D, de Bock, Geertruida H., Ph.D, van der Zee, Ate G.J., M.D., Ph.D

“…The aim of this study was to systematically review the prognostic and predictive significance of cell biological markers in cervical cancer patients primarily…”
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ARID1A mutant ovarian clear cell carcinoma: A clear target for synthetic lethal strategies by Caumanns, Joseph J., Wisman, G. Bea A., Berns, Katrien, van der Zee, Ate G.J., de Jong, Steven

“…SWI/SNF chromatin remodeling complexes play an important role in the epigenetic regulation of chromatin structure and gene transcription. Mutual exclusive…”
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The role of ATM and 53BP1 as predictive markers in cervical cancer by Roossink, Frank, Wieringa, Hylke W., Noordhuis, Maartje G., ten Hoor, Klaske A., Kok, Mirjam, Slagter-Menkema, Lorian, Hollema, Harry, de Bock, Geertruida H., Pras, Elisabeth, de Vries, Elisabeth G.E., de Jong, Steven, van der Zee, Ate G.J., Schuuring, Ed, Wisman, G. Bea A., van Vugt, Marcel A.T.M.

“…Treatment of advanced‐stage cervical cancers with (chemo)radiation causes cytotoxicity through induction of high levels of DNA damage. Tumour cells respond to…”
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Comparing the Cervista HPV HR test and Hybrid Capture 2 assay in a Dutch screening population: improved specificity of the Cervista HPV HR test by changing the cut-off by Boers, Aniek, Slagter-Menkema, Lorian, van Hemel, Bettien M, Belinson, Jerome L, Ruitenbeek, Teus, Buikema, Henk J, Klip, Harry, Ghyssaert, Hilde, van der Zee, Ate G J, de Bock, Geertruida H, Wisman, G Bea A, Schuuring, Ed

“…The diagnostic performance of the widely-used Cervista HPV HR test was compared to the Hybrid Capture 2 (HC2) test in a Dutch population-based cervical cancer…”
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CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer by Komdeur, Fenne L., Prins, Thalina M., van de Wall, Stephanie, Plat, Annechien, Wisman, G. Bea A., Hollema, Harry, Daemen, Toos, Church, David N., de Bruyn, Marco, Nijman, Hans W.

“…Human papilloma virus (HPV)-induced cervical cancer constitutively expresses viral E6/E7 oncoproteins and is an excellent target for T cell-based…”
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DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population by Li, Na, Hu, Yuanjing, Zhang, Xinying, Liu, Yixin, He, Ya, Zee, Ate G. J., Schuuring, Ed, Wisman, G. Bea A

“…Objective strategies are required in cervical cancer screening. We have identified several DNA methylation markers with high sensitivity and specificity to…”
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CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma by Workel, Hagma H, Komdeur, Fenne L, Wouters, Maartje C.A, Plat, Annechien, Klip, Harry G, Eggink, Florine A, Wisman, G. Bea A, Arts, Henriette J.G, Oonk, Maaike H.M, Mourits, Marian J.E, Yigit, Refika, Versluis, Marco, Duiker, Evelien W, Hollema, Harry, de Bruyn, Marco, Nijman, Hans W

“…Abstract Introduction Intraepithelial CD8+ tumour-infiltrating T-lymphocytes (TIL) are associated with a prolonged survival in endometrial cancer (EC). By…”
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Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer by Flanagan, James M, Wilson, Angela, Koo, Chail, Masrour, Nahal, Gallon, John, Loomis, Erick, Flower, Kirsty, Wilhelm-Benartzi, Charlotte, Hergovich, Alexander, Cunnea, Paula, Gabra, Hani, Braicu, Elena Ioana, Sehouli, Jalid, Darb-Esfahani, Silvia, Vanderstichele, Adriaan, Vergote, Ignace, Kreuzinger, Caroline, Castillo-Tong, Dan Cacsire, Wisman, G Bea A, Berns, Els Mjj, Siddiqui, Nadeem, Paul, James, Brown, Robert

“…DNA damage repair can lead to epigenetic changes. DNA mismatch repair proteins bind to platinum DNA adducts and at sites of DNA damage can recruit the DNA…”
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Genome-wide DNA Methylation Profiling Reveals Methylation Markers Associated with 3q Gain for Detection of Cervical Precancer and Cancer by Verlaat, Wina, Snijders, Peter J F, Novianti, Putri W, Wilting, Saskia M, De Strooper, Lise M A, Trooskens, Geert, Vandersmissen, Johan, Van Criekinge, Wim, Wisman, G Bea A, Meijer, Chris J L M, Heideman, Daniëlle A M, Steenbergen, Renske D M

“…Epigenetic host cell changes involved in cervical cancer development following a persistent high-risk human papillomavirus (hrHPV) infection, provide promising…”
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HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer by Teschendorff, Andrew E, Lee, Shih-Han, Jones, Allison, Fiegl, Heidi, Kalwa, Marie, Wagner, Wolfgang, Chindera, Kantaraja, Evans, Iona, Dubeau, Louis, Orjalo, Arturo, Horlings, Hugo M, Niederreiter, Lukas, Kaser, Arthur, Yang, Winnie, Goode, Ellen L, Fridley, Brooke L, Jenner, Richard G, Berns, Els M J J, Wik, Elisabeth, Salvesen, Helga B, Wisman, G Bea A, van der Zee, Ate G J, Davidson, Ben, Trope, Claes G, Lambrechts, Sandrina, Vergote, Ignace, Calvert, Hilary, Jacobs, Ian J, Widschwendter, Martin

“…Understanding carboplatin resistance in ovarian cancer is critical for the improvement of patients' lives. Multipotent mesenchymal stem cells or an aggravated…”
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