Search Results - "Wisidagama, Dona R R"
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Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells
Published in Nature protocols (01-06-2012)“…Measurements of glycolysis and mitochondrial function are required to quantify energy metabolism in a wide variety of cellular contexts. In human pluripotent…”
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Regulation of Drosophila Intestinal Stem Cell Proliferation by Enterocyte Mitochondrial Pyruvate Metabolism
Published in G3 : genes - genomes - genetics (01-11-2019)“…Multiple signaling pathways in the adult enterocyte sense cellular damage or stress and signal to intestinal stem cells (ISCs) to undergo proliferation and…”
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A host beetle pheromone regulates development and behavior in the nematode Pristionchus pacificus
Published in eLife (15-10-2014)“…Nematodes and insects are the two most speciose animal phyla and nematode-insect associations encompass widespread biological interactions. To dissect the…”
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An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion
Published in Molecular metabolism (Germany) (01-08-2016)“…Abstract Objective Transport of pyruvate into the mitochondrial matrix by the Mitochondrial Pyruvate Carrier (MPC) is an important and rate-limiting step in…”
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Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism
Published in Nature cell biology (01-09-2017)“…Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes…”
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Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
Published in Cell metabolism (04-02-2020)“…Although metabolic adaptations have been demonstrated to be essential for tumor cell proliferation, the metabolic underpinnings of tumor initiation are poorly…”
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Functional analysis of Aarf domain‐containing kinase 1 in Drosophila melanogaster
Published in Developmental dynamics (01-09-2019)“…Background The ADCK proteins are predicted mitochondrial kinases. Most studies of these proteins have focused on the Abc1/Coq8 subfamily, which contributes to…”
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Defining the Role of Oxygen Tension in Human Neural Progenitor Fate
Published in Stem cell reports (11-11-2014)“…Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the…”
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