Search Results - "Wise, Matthew P"
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Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33°C and 36°C
Published in Journal of the American College of Cardiology (19-05-2015)“…Abstract Background Neuron-specific enolase (NSE) is a widely-used biomarker for prognostication of neurological outcome after cardiac arrest, but the…”
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Protocol-driven neurological prognostication and withdrawal of life-sustaining therapy after cardiac arrest and targeted temperature management
Published in Resuscitation (01-08-2017)“…Abstract Background Brain injury is reportedly the main cause of death for patients resuscitated after out-of-hospital cardiac arrest (OHCA). However, the…”
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Single versus Serial Measurements of Neuron-Specific Enolase and Prediction of Poor Neurological Outcome in Persistently Unconscious Patients after Out-Of-Hospital Cardiac Arrest - A TTM-Trial Substudy
Published in PloS one (18-01-2017)“…Prediction of neurological outcome is a crucial part of post cardiac arrest care and prediction in patients remaining unconscious and/or sedated after…”
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Neuropsychological outcome after cardiac arrest: results from a sub-study of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
Published in Critical care (London, England) (26-08-2023)“…Abstract Background Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our…”
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Renal function after out-of-hospital cardiac arrest; the influence of temperature management and coronary angiography, a post hoc study of the target temperature management trial
Published in Critical care (London, England) (08-05-2019)“…To elucidate the incidence of acute kidney injury (AKI) after out-of-hospital cardiac arrest (OHCA) and to examine the impact of target temperature management…”
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Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data
Published in Critical care (London, England) (26-11-2016)“…Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was…”
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Circulating Levels of Brain-Enriched MicroRNAs Correlate with Neuron Specific Enolase after Cardiac Arrest-A Substudy of the Target Temperature Management Trial
Published in International journal of molecular sciences (19-06-2020)“…Outcome prognostication after cardiac arrest (CA) is challenging. Current multimodal prediction approaches would benefit from new biomarkers. MicroRNAs…”
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Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest
Published in Resuscitation (01-06-2015)“…Abstract Aim To assess older age as a prognostic factor in patients resuscitated from out-of-hospital-cardiac arrest (OHCA) and the interaction between age and…”
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Impact of time to return of spontaneous circulation on neuroprotective effect of targeted temperature management at 33 or 36 degrees in comatose survivors of out-of hospital cardiac arrest
Published in Resuscitation (01-11-2015)“…Abstract Aim Time to Return of Spontaneous Circulation (ROSC) has a plausible relation to severity of hypoxic injury before and during resuscitation in…”
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COVID-19 and fungal infection: the need for a strategic approach
Published in The Lancet. Microbe (01-09-2020)Get full text
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Circular RNAs to predict clinical outcome after cardiac arrest
Published in Intensive care medicine experimental (28-10-2022)“…Background Cardiac arrest (CA) represents the third leading cause of death worldwide. Among patients resuscitated and admitted to hospital, death and severe…”
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Desmopressin for prevention of bleeding for thrombocytopenic, critically ill patients undergoing invasive procedures: A randomised, double‐blind, placebo‐controlled feasibility trial
Published in EJHaem (01-08-2024)“…Thrombocytopenic patients have an increased risk of bleeding when undergoing invasive procedures. In a multicentre, phase II, blinded, randomised, controlled…”
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Neuropsychological outcome after cardiac arrest: a prospective case control sub-study of the Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest trial (TTM2)
Published in BMC cardiovascular disorders (07-10-2020)“…This study is designed to provide detailed knowledge on cognitive impairment after out-of-hospital cardiac arrest (OHCA) and its relation to associated…”
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Correction: Circular RNAs to predict clinical outcome after cardiac arrest
Published in Intensive care medicine experimental (09-11-2022)Get full text
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Usefulness of Serum B-type Natriuretic Peptide Levels in Comatose Patients Resuscitated from Out-Of-Hospital Cardiac Arrest to Predict Outcome
Published in The American journal of cardiology (01-10-2016)“…Abstract N-terminal pro B-type natriuretic (NT-proBNP) is expressed in the heart and brain and serum levels are elevated in acute heart and brain diseases. We…”
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A National Strategy to Diagnose Coronavirus Disease 2019–Associated Invasive Fungal Disease in the Intensive Care Unit
Published in Clinical infectious diseases (05-10-2021)“…Abstract Background Fungal coinfection is a recognized complication of respiratory virus infections, increasing morbidity and mortality, but can be readily…”
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Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest: a statistical analysis plan
Published in Current controlled trials in cardiovascular medicine (07-10-2020)“…Abstract Background To date, targeted temperature management (TTM) is the only neuroprotective intervention after resuscitation from cardiac arrest that is…”
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Lopinavir–ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Published in The Lancet (British edition) (24-10-2020)“…Lopinavir–ritonavir has been proposed as a treatment for COVID-19 on the basis of in vitro activity, preclinical studies, and observational studies. Here, we…”
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Acute cor pulmonale as a confounder in trials of ECMO or prone ventilation in ARDS
Published in Intensive care medicine (04-09-2024)Get full text
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Physical activity after cardiac arrest; protocol of a sub-study in the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2)
Published in Resuscitation plus (01-03-2021)“…•The results of this study will provide novel information about physical activity among OHCA-survivors.•Physical activity after a cardiac arrest is currently…”
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