Search Results - "Wise, Hannah"

Precision Oncology: Three Small Steps Forward by Wise, Hannah C, Solit, David B

“…Only a subset of cancer patients currently benefit from personalized treatment approaches. Detection of actionable drug targets in cell-free DNA, more…”
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Activity of M3814, an Oral DNA-PK Inhibitor, In Combination with Topoisomerase II Inhibitors in Ovarian Cancer Models by Wise, Hannah C., Iyer, Gopakumar V., Moore, Kathleen, Temkin, Sarah M., Gordon, Sarah, Aghajanian, Carol, Grisham, Rachel N.

“…DNA-dependent protein kinase (DNA-PK) has been shown to play a crucial role in repair of DNA double-strand breaks, facilitating nonhomologous end-joining…”
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Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer by Hanrahan, Aphrothiti J, Sylvester, Brooke E, Chang, Matthew T, Elzein, Arijh, Gao, Jianjiong, Han, Weiwei, Liu, Ye, Xu, Dong, Gao, Sizhi P, Gorelick, Alexander N, Jones, Alexis M, Kiliti, Amber J, Nissan, Moriah H, Nimura, Clare A, Poteshman, Abigail N, Yao, Zhan, Gao, Yijun, Hu, Wenhuo, Wise, Hannah C, Gavrila, Elena I, Shoushtari, Alexander N, Tiwari, Shakuntala, Viale, Agnes, Abdel-Wahab, Omar, Merghoub, Taha, Berger, Michael F, Rosen, Neal, Taylor, Barry S, Solit, David B

“…Despite significant advances in cancer precision medicine, a significant hurdle to its broader adoption remains the multitude of variants of unknown…”
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AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling by Gao, Sizhi Paul, Kiliti, Amber J, Zhang, Kai, Vasani, Naresh, Mao, Ninghui, Jordan, Emmet, Wise, Hannah C, Shrestha Bhattarai, Tripti, Hu, Wenhuo, Dorso, Madeline, Rodrigues, James A, Kim, Kwanghee, Hanrahan, Aphrothiti J, Razavi, Pedram, Carver, Brett, Chandarlapaty, Sarat, Reis-Filho, Jorge S, Taylor, Barry S, Solit, David B

“…Mutational activation of the PI3K/AKT pathway is among the most common pro-oncogenic events in human cancers. The clinical utility of PI3K and AKT inhibitors…”
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Feasibility and safety of a novel electromagnetic device for small-bore feeding tube placement by Jacobson, Lewis E, Olayan, May, Williams, Jamie M, Schultz, Jacqueline F, Wise, Hannah M, Singh, Amandeep, Saxe, Jonathan M, Benjamin, Richard, Emery, Marie, Vilem, Hilary, Kirby, Donald F

“…BackgroundMisplacement of enteral feeding tubes (EFT) in the lungs is a serious and potentially fatal event. A recent Food and Drug Administration Patient…”
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Abstract 4144721: The role of Na + /K + ATPase alpha 1 subunit in the sex-difference-associated high risk of thrombosis by Li, Angela, Yue, Hong, Wise, Hannah, Li, Wei

“…Abstract only Background: Significant sex differences in the risk of thrombosis-related diseases such as myocardial infarction, stroke, and venous…”
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Psychometric synthesis of the Alcohol Use Disorders Identification Test (AUDIT) by Chen, Yutong, Wills, Leann, Wise, Hannah, Erford, Bradley T., Yao, Ruonan

“…Hazardous or harmful alcohol use is very prevalent among the US population. With 15.1 million adults in the United States currently identified as having an…”
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Feasibility of Capturing AML Morphologic Response Assessments Using Real-World Data by Guinter, Mark, Kim, Hankyul, Jacob, Alexandra, Wise, Hannah, Cha, Kyusun, Sawas, Ahmed

“…Background: Response in acute myeloid leukemia (AML) is based on morphologic evaluation of bone marrow (BM) and peripheral blood lab-based assessments…”
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Escape the welcome cliché: Designing educational escape rooms to enhance students’ learning experience by Wise, Hannah, Lowe, Julie, Hill, Adam, Barnett, Laura, Barton, Charlotte

“…The University of Surrey Library and Learning Support Services (LLSS) recognised an increasing need to transform its welcome, induction and orientation…”
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KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer by Qiu, Hong, Makarov, Vladimir, Bolzenius, Jennifer K, Halstead, Angela, Parker, Yvonne, Wang, Allen, Iyer, Gopakumar V, Wise, Hannah, Kim, Daniel, Thayaparan, Varna, Lindner, Daniel J, Haber, Georges-Pascal, Ting, Angela H, Ren, Bing, Chan, Timothy A, Arora, Vivek, Solit, David B, Lee, Byron H

“…Disruption of KDM6A, a histone lysine demethylase, is one of the most common somatic alternations in bladder cancer. Insights into how KDM6A mutations affect…”
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Antibiotic consumption and time to recovery from uncomplicated urinary tract infection: secondary analysis of observational data from a point-of-care test trial by Gadalla, Amal, Wise, Hannah, Farewell, Daniel, Hughes, Kathryn, Llor, Carl, Moore, Michael, Verheij, Theo JM, Little, Paul, Butler, Christopher C, Francis, Nick A

“…Background Randomised trials provide high-quality evidence on the effects of prescribing antibiotics for urinary tract infection (UTI) but may not reflect the…”
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Genomic heterogeneity as a barrier to precision oncology in urothelial cancer by Clinton, Timothy N., Chen, Ziyu, Wise, Hannah, Lenis, Andrew T., Chavan, Shweta, Donoghue, Mark T.A., Almassi, Nima, Chu, Carissa E., Dason, Shawn, Rao, Pavitra, Rodrigues, James A., Vasani, Naresh B., Ridouani, Fourat, Rosenberg, Jonathan E., Bajorin, Dean F., Teo, Min Yuen, Bochner, Bernard H., Berger, Michael F., Ostrovnaya, Irina, Pietzak, Eugene J., Iyer, Gopa, Gao, Sizhi Paul, Hu, Wenhuo, Al-Ahmadie, Hikmat A., Solit, David B.

“…Precision oncology relies on the accurate molecular characterization of individual patients with cancer at the time of treatment initiation. However, tumor…”
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PD42-06 DEFINING THE GENETIC EVOLUTION OF EPIGENETIC ALTERATIONS IN BLADDER CANCER by Clinton, Timothy, Wise, Hannah, Almassi, Nima, Chavan, Shweta, Hu, Wenhuo, Dason, Shawn, Pietzak, Eugene, Cha, Eugene, Dalbagni, Guido, Iyer, Gopa, Bochner, Bernard, Rosenberg, Jonathan, Bajorin, Dean, Arcila, Maria, Al-Ahmadie, Hikmat, Taylor, Barry, Solit, David

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Defining the genetic evolution of epigenetic alterations in bladder cancer by Clinton, Timothy Nguyen, Wise, Hannah, Almassi, Nima, Chavan, Shweta S., Hu, Wenhuo, Gao, Sizhi Paul, Hanrahan, Aphrothiti, Dason, Shawn, Pietzak, Eugene J., Carlo, Maria Isabel, Funt, Samuel Aaron, Teo, Min Yuen, Iyer, Gopa, Bochner, Bernard H., Rosenberg, Jonathan E., Bajorin, Dean F., Arcila, Maria E., Al-Ahmadie, Hikmat, Taylor, Barry S., Solit, David B.

“…Abstract only 529 Background: Large-scale efforts have sought to define the genomic landscape of urothelial carcinomas of the bladder with the goal of…”
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Escape the welcome cliché by Wise, Hannah, Lowe, Julie, Hill, Adam, Barnett, Laura, Barton, Charlotte

“…The University of Surrey Library and Learning Support Services (LLSS) recognised an increasing need to transform its welcome, induction and orientation…”
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