Search Results - "Wirz, Angela"

Abdominal Compression by Waist Belt Aggravates Gastroesophageal Reflux, primarily by Impairing Esophageal Clearance by Mitchell, David R, Derakhshan, Mohammad H, Wirz, Angela A, Ballantyne, Stuart A, McColl, Kenneth E.L

“…Background & Aims Central obesity promotes gastroesophageal reflux, which may be related to increased intra-abdominal pressure. We investigated the effect of…”
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Central Obesity in Asymptomatic Volunteers Is Associated With Increased Intrasphincteric Acid Reflux and Lengthening of the Cardiac Mucosa by Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Lee, Yeong Yeh, Seenan, John Paul, Ballantyne, Stuart A, Hanvey, Scott L, Kelman, Andrew W, Going, James J, McColl, Kenneth E.L

“…Background & Aims In the West, a substantial proportion of subjects with adenocarcinoma of the gastric cardia and gastroesophageal junction have no history…”
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In healthy volunteers, immunohistochemistry supports squamous to columnar metaplasia as mechanism of expansion of cardia, aggravated by central obesity by Derakhshan, Mohammad H, Robertson, Elaine V, Yeh Lee, Yeong, Harvey, Tim, Ferrier, Rod K, Wirz, Angela A, Orange, Clare, Ballantyne, Stuart A, Hanvey, Scott L, Going, James J, McColl, Kenneth E L

“…Recently, we showed that the length of cardiac mucosa in healthy volunteers correlated with age and obesity. We have now examined the immunohistological…”
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Waist belt and central obesity cause partial hiatus hernia and short-segment acid reflux in asymptomatic volunteers by Lee, Yeong Yeh, Wirz, Angela A, Whiting, James G H, Robertson, Elaine V, Smith, Donald, Weir, Alexander, Kelman, Andrew W, Derakhshan, Mohammad H, McColl, Kenneth E L

“…There is a high incidence of inflammation and metaplasia at the gastro-oesophageal junction (GOJ) in asymptomatic volunteers. Additionally, the majority of…”
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The gastric acid pocket is attenuated in H. pylori infected subjects by Mitchell, David R, Derakhshan, Mohammad H, Wirz, Angela A, Orange, Clare, Ballantyne, Stuart A, Going, James J, McColl, Kenneth E L

“…Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in positive and negative volunteers in a…”
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Mechanism of association between BMI and dysfunction of the gastro-oesophageal barrier in patients with normal endoscopy by Derakhshan, Mohammad H, Robertson, Elaine V, Fletcher, Jonathan, Jones, Gareth-Rhys, Lee, Yeong Yeh, Wirz, Angela A, McColl, Kenneth E L

“…The association between body mass index (BMI) and gastro-oesophageal pressure gradient (GOPG) is incompletely understood. We examined the association between…”
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Hiatus hernia in healthy volunteers is associated with intrasphincteric reflux and cardiac mucosal lengthening without traditional reflux by Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Mitchell, David R, Going, James J, Kelman, Andrew W, Ballantyne, Stuart A, McColl, Kenneth E L

“…Hiatus hernia (HH) is a key mediator of gastro-oesophageal reflux disease but little is known about its significance in the general population. We studied the…”
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Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal by Fletcher, Jonathan, Wirz, Angela, Young, Joanne, Vallance, Ramsey, McColl, Kenneth E.L.

“…Background & Aims: Gastroesophageal reflux typically occurs after meals. During dual gastric and esophageal pH monitoring, we observed that postprandial…”
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BMI is superior to symptoms in predicting response to proton pump inhibitor: randomised trial in patients with upper gastrointestinal symptoms and normal endoscopy by Fletcher, Jonathan, Derakhshan, Mohammad H, Jones, Gareth-Rhys, Wirz, Angela A, McColl, Kenneth E L

“…In most patients undergoing endoscopy for upper gastrointestinal (GI) symptoms in the Western world, no macroscopic abnormality or evidence of Helicobacter…”
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Tu1196 Partial Hiatus Herniation Occurs in Asymptomatic Individuals With Central Obesity or With Abdominal Belt Compression by Lee, Yeong Yeh, Whiting, James, Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Morrison, Douglas, Weir, Alexander J, Smith, Donald, McColl, Kenneth E

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15 In Asymptomatic Volunteers Inflammatory and Immunohistological Characteristics of Go Junction Indicates Squamo-Columnar Metaplasia Aggravated by Central Obesity by Derakhshan, Mohammad H, Robertson, Elaine V, Harvey, Tim, Ferrier, Rod K, Orange, Clare, Wirz, Angela A, Ballantyne, Stuart, Going, James J, McColl, Kenneth E

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Helicobacter pylori eradication releases prolonged increased acid secretion following omeprazole treatment by Gillen, Derek, Wirz, Angela A., McColl, Kenneth E.L.

“…Background & Aims : Rebound increased acid secretion has been observed at 2 weeks after discontinuing omeprazole treatment in Helicobacter pylori-negative, but…”
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Increased prevalence of precancerous changes in relatives of gastric cancer patients: Critical role of H. pylori by El–Omar, Emad M., Oien ‡,§, Karin, Murray, Lilian S., El–Nujumi, Adil, Wirz, Angela, Gillen, Derek, Williams ∥, Craig, Fullarton ¶, Grant, McColl, Kenneth E.L.

“…Background & Aims: Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of…”
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428 Characterization of Proximal Movement of Gastro-Oesophageal Junction During Transient Lower Oesophageal Sphincter Relaxations Using a Novel Hall Effect Probe by Lee, Yeong Yeh, Whiting, James, Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Kelman, Andrew W, McColl, Kenneth E

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Tu1142 Central Obesity and Age Predict Cardia Mucosal Length in Healthy Volunteers: Evidence for an Acquired Entity by Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Lee, Yeong Yeh, Going, James J, Hanvey, Scott, Ballantyne, Stuart, McColl, Kenneth E

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Effect of nitrite delivered in saliva on postprandial gastro-esophageal function by Seenan, John P., Wirz, Angela A., Robertson, Elaine V., Clarke, Alan T., Manning, Jonathan J., Kelman, Andrew W., Gillen, Gerry, Ballantyne, Stuart, Derakhshan, MohammaD H., McColl, Kenneth E.L.

“…Abstract Objective. Acid reflux produces troublesome symptoms (heartburn) and complications including esophagitis, Barrett's esophagus, and adenocarcinoma…”
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Squamo-Columnar Junction Locator Probe: From Bench to In-Vivo Study by Lee, Yeong Yeh, Whiting, James, Robertson, Elaine V, Seenan, John P, Derakhshan, Mohammad H, Wirz, Angela A, Connolly, Patricia, McColl, Kenneth E

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High Resolution Oesophageal Manometry: Addressing Thermal Drift by Robertson, Elaine V, Lee, Yeong Yeh, Derakhshan, Mohammad H, Whiting, James, Wirz, Angela A, Seenan, John P, McColl, Kenneth E

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Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation by Mowat, Craig, Williams, Craig, Gillen, Derek, Hossack, Margaret, Gilmour, Denise, Carswell, Andrew, Wirz, Angela, Preston, Tom, McColl, Kenneth E.L.

“…Background & Aims: Omeprazole produces greater acid inhibition in Helicobacter pylori–positive than –negative subjects. We investigated whether this is…”
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Development and validation of a probe allowing accurate and continuous monitoring of location of squamo-columnar junction by Lee, Yeong Yeh, Seenan, John P, Whiting, James G.H, Robertson, Elaine V, Derakhshan, Mohammad H, Wirz, Angela A, Smith, Donald, Hardy, Chris, Kelman, Andrew, Connolly, Patricia, McColl, Kenneth E.L

“…Abstract Introduction Most pathology of the upper gastrointestinal tract now occurs close to the gastro-oesophageal squamo-columnar junction (SCJ). Studying…”
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