Search Results - "Wirth, W"

A Technique for Regional Analysis of Femorotibial Cartilage Thickness Based on Quantitative Magnetic Resonance Imaging by Wirth, W., Eckstein, F.

“…The objective of this work was to develop a methodology for measuring cartilage thickness in anatomically based subregions in the tibial and in the central…”
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Osteoarthritis year in review 2020: imaging by Eckstein, F., Wirth, W., Culvenor, A.G.

“…This narrative “Year in Review” highlights a selection of articles published between January 2019 and April 2020, to be presented at the OARSI World Congress…”
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Imaging in Osteoarthritis by Roemer, F.W., Guermazi, A., Demehri, S., Wirth, W., Kijowski, R.

“…Osteoarthritis (OA) is the most frequent form of arthritis with major implications on both individual and public health care levels. The field of joint…”
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Quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis – data from the Osteoarthritis Initiative by Emmanuel, K, Quinn, E, Niu, J, Guermazi, A, Roemer, F, Wirth, W, Eckstein, F, Felson, D

“…Summary Objective To test the hypothesis that quantitative measures of meniscus extrusion predict incident radiographic knee osteoarthritis (KOA), prior to the…”
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The role of thigh muscle and adipose tissue in knee osteoarthritis progression in women: data from the Osteoarthritis Initiative by Kemnitz, J., Wirth, W., Eckstein, F., Culvenor, A.G.

“…To determine whether loss in thigh muscle strength in women concurrent with knee osteoarthritis progression is associated with reductions of muscle anatomical…”
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Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative by Wirth, W., Hunter, D.J., Nevitt, M.C., Sharma, L., Kwoh, C.K., Ladel, C., Eckstein, F.

“…To investigate the predictive and concurrent validity of magnetic resonance imaging (MRI)-based cartilage thickness change between baseline (BL) and year-two…”
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Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants by Ruhdorfer, A, Wirth, W, Eckstein, F

“…Summary Objective To cross-sectionally determine the quantitative relationship of age-adjusted, sex-specific isometric knee extensor and flexor strength to…”
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Cartilage loss in radiographically normal knees depends on radiographic status of the contralateral knee – data from the Osteoarthritis Initiative by Eckstein, F., Maschek, S., Roemer, F.W., Duda, G.N., Sharma, L., Wirth, W.

“…To test whether radiographically normal knees with contralateral radiographic knee osteoarthritis (OA), but without contralateral trauma history, display…”
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Relationship Between Medial Meniscal Extrusion and Cartilage Loss in Specific Femorotibial Subregions: Data From the Osteoarthritis Initiative by Bloecker, K., Wirth, W., Guermazi, A., Hunter, D. J., Resch, H., Hochreiter, J., Eckstein, F.

“…Objective Medial meniscal extrusion is known to be related to structural progression of knee osteoarthritis. However, it is unclear whether medial meniscal…”
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Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from the Osteoarthritis Initiative (OAI) by Wirth, W, Maschek, S, Beringer, P, Eckstein, F

“…Summary Objective To explore whether subregional laminar femorotibial cartilage spin–spin relaxation time (T2) is associated with subsequent radiographic…”
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Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis by Eckstein, F, Guermazi, A, Gold, G, Duryea, J, Hellio Le Graverand, M.-P, Wirth, W, Miller, C.G

“…Summary Imaging in clinical trials is used to evaluate subject eligibility, and/or efficacy of intervention, supporting decision making in drug development by…”
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Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative by Moyer, R, Wirth, W, Duryea, J, Eckstein, F

“…Summary Objective To determine how frontal plane lower limb alignment obtained using a new femorotibial angle (FTA) measurement and non-radiographic handheld…”
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Five‐Year Followup of Knee Joint Cartilage Thickness Changes After Acute Rupture of the Anterior Cruciate Ligament by Eckstein, F., Wirth, W., Lohmander, L. S., Hudelmaier, M. I., Frobell, R. B.

“…Objective Anterior cruciate ligament (ACL) rupture involves an increased risk of osteoarthritis. The purpose of this study was to explore changes in cartilage…”
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Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort by Wirth, W., M.S, Hellio Le Graverand, M.-P., M.D, Wyman, B.T., Ph.D, Maschek, S., Ph.D, Hudelmaier, M., M.D, Hitzl, W., Ph.D, Nevitt, M., Ph.D, Eckstein, F., M.D

“…Summary Objective The Osteoarthritis Initiative (OAI) is aimed at validating (imaging) biomarkers for monitoring progression of knee OA. Here we analyze…”
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Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative by Bloecker, K, Guermazi, A, Wirth, W, Benichou, O, Kwoh, C.K, Hunter, D.J, Englund, M, Resch, H, Eckstein, F

“…Summary Introduction Meniscal extrusion is thought to be associated with less meniscus coverage of the tibial surface, but the association of radiographic…”
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TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice by Thiele, Nina D., Wirth, Jan W., Steins, David, Koop, Anja C., Ittrich, Harald, Lohse, Ansgar W., Kluwe, Johannes

“…Tissue inhibitor of metalloproteinases-1 (TIMP-1) is upregulated during hepatic fibrogenesis and considered to promote fibrosis in the injured liver by…”
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Longitudinal change in thigh muscle strength prior to and concurrent with symptomatic and radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative by Kemnitz, J., Wirth, W., Eckstein, F., Ruhdorfer, A., Culvenor, A.G.

“…To investigate whether symptomatic and/or radiographic knee osteoarthritis (KOA) progression is associated with prior and/or concurrent change in thigh muscle…”
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Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively defined cartilage thickness loss in knee osteoarthritis: the Multicenter Osteoarthritis Study by Guermazi, A, Eckstein, F, Hayashi, D, Roemer, F.W, Wirth, W, Yang, T, Niu, J, Sharma, L, Nevitt, M.C, Lewis, C.E, Torner, J, Felson, D.T

“…Summary Objectives To provide a comprehensive simultaneous relation of various semiquantitative knee OA MRI features as well as the presence of baseline…”
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Radiographically normal knees with contralateral joint space narrowing display greater change in cartilage transverse relaxation time than those with normal contralateral knees: a model of early OA? – data from the Osteoarthritis Initiative (OAI) by Wirth, W., Maschek, S., Roemer, F.W., Sharma, L., Duda, G.N., Eckstein, F.

“…To develop a model of early osteoarthritis, by examining whether radiographically normal knees with contralateral joint space narrowing (JSN), but without…”
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Association between osteoarthritis-related serum biochemical markers over 11 years and knee MRI-based imaging biomarkers in middle-aged adults by Singh, A., Venn, A., Blizzard, L., Jones, G., Burgess, J., Parameswaran, V., Cicuttini, F., March, L., Eckstein, F., Wirth, W., Ding, C., Antony, B.

“…To describe the associations between osteoarthritis (OA)-related biochemical markers (COMP, MMP-3, HA) and MRI-based imaging biomarkers in middle-aged adults…”
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