Search Results - "Wirth, Thomas"

Novel Organic Synthesis through Ultrafast Chemistry by Wirth, Thomas

“…How fast are flashes? The field of flow chemistry has recently received increasing attention owing to the availability of commercial flow equipment. New…”
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Electroorganic Synthesis under Flow Conditions by Elsherbini, Mohamed, Wirth, Thomas

“…Conspectus Despite the long history of electroorganic synthesis, it did not participate in the mainstream of chemical research for a long time. This is…”
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Hypervalent Iodine Reagents by Anodic Oxidation: A Powerful Green Synthesis by Elsherbini, Mohamed, Wirth, Thomas

“…The anodic oxidation of aryl iodides is a powerful method for the synthesis of hypervalent iodine reagents, which eliminates the necessity to use expensive or…”
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Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes by Amri, Nasser, Wirth, Thomas

“…An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides to N-cyanosulfoximines has been…”
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Hypervalent Iodine Chemistry in Synthesis: Scope and New Directions by Wirth, Thomas

“…The impressive development of hypervalent iodine chemistry in recent years is reflected by the number of publications in this area. Although the synthesis of…”
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Highly Stereoselective Metal-Free Oxyaminations Using Chiral Hypervalent Iodine Reagents by Farid, Umar, Wirth, Thomas

“…The ring and I: Hypervalent iodine compounds avoid the issues of toxicity or complicated ligands of many transition‐metal‐based systems. A highly…”
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Recent Advances in the Electrochemical Synthesis of Organosulfur Compounds by Amri, Nasser, Wirth, Thomas

“…Organosulfur compounds are being widely used in medicinal chemistry, as well as in organic transformations and in synthetic applications. Because of their…”
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Hypervalent Iodine-Catalyzed Oxidative Functionalizations Including Stereoselective Reactions by Singh, Fateh V., Wirth, Thomas

“…Hypervalent iodine chemistry is now a well‐established area of organic chemistry. Novel hypervalent iodine reagents have been introduced in many different…”
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Crosstalk between Tumor and Stromal Cells in Pancreatic Ductal Adenocarcinoma by Sperb, Nadine, Tsesmelis, Miltiadis, Wirth, Thomas

“…Pancreatic ductal adenocarcinoma (PDAC) remains a lethal cancer. The poor prognosis calls for a more detailed understanding of disease biology in order to pave…”
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Advances in the understanding of MYC‐induced lymphomagenesis by Klapproth, Kay, Wirth, Thomas

“…Summary Up to 70% of all human malignancies show elevated expression of MYC. MYC is a pleiotropic transcription factor involved in many aspects of cellular…”
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Electrocatalytic continuous flow chlorinations with iodine(I/III) mediators by Patra, Tuhin, Arepally, Sagar, Seitz, Jakob, Wirth, Thomas

“…Electrochemistry offers tunable, cost effective and environmentally friendly alternatives to carry out redox reactions with electrons as traceless reagents…”
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FOXO in B-cell lymphopoiesis and B cell neoplasia by Ushmorov, Alexey, Wirth, Thomas

“…FOX O family transcription factors are important for differentiation and function of multiple cell types. In B lymphocytes they play a critical role. The…”
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An Easy‐to‐Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization by Folgueiras‐Amador, Ana A., Philipps, Kai, Guilbaud, Sébastien, Poelakker, Jarno, Wirth, Thomas

“…Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to…”
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Flow Chemistry: Enabling Technology in Drug Discovery and Process Research by Wirth, Thomas

“…Editorial: Flow chemistry has now found its way into research and development, not only in academic institutions, but also in industry. This special issue of…”
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Selenium-Catalyzed Regioselective Cyclization of Unsaturated Carboxylic Acids Using Hypervalent Iodine Oxidants by Singh, Fateh V, Wirth, Thomas

“…A new and convenient selenium-catalyzed regioselective cyclization of γ,δ-unsaturated carboxylic acids to the corresponding 3,6-dihydro-2H-pyran-2-ones is…”
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Continuous‐Flow Electrochemical Generator of Hypervalent Iodine Reagents: Synthetic Applications by Elsherbini, Mohamed, Winterson, Bethan, Alharbi, Haifa, Folgueiras‐Amador, Ana A., Génot, Célina, Wirth, Thomas

“…An efficient and reliable electrochemical generator of hypervalent iodine reagents has been developed. In the anodic oxidation of iodoarenes to hypervalent…”
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Chiral Triptycenes: Concepts, Progress and Prospects by Khan, Md. Nasim, Wirth, Thomas

“…Triptycenes have been established as unique scaffolds because of their backbone π‐structure with a propeller‐like shape and saddle‐like cavities. They are some…”
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Surveillance in cholangiocellular carcinoma by Wirth, Thomas C., Dr, Vogel, Arndt, Prof. Dr

“…Abstract Cholangiocellular carcinoma is the most frequent malignant neoplasm originating from the epithelium of intra- or extrahepatic bile ducts. In the past…”
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Hypervalent iodine chemistry and light: photochemical reactions involving hypervalent iodine chemistry by Singh, Fateh V., Wirth, Thomas

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Transcriptome Profiling Identifies TIGIT as a Marker of T‐Cell Exhaustion in Liver Cancer by Ostroumov, Dmitrij, Duong, Steven, Wingerath, Jessica, Woller, Norman, Manns, Michael P., Timrott, Kai, Kleine, Moritz, Ramackers, Wolf, Roessler, Stephanie, Nahnsen, Sven, immunoglobulin and immunoreceptor tyrosiCzemmel, Dittrich‐Breiholz, Oliver, Eggert, Tobias, Kühnel, Florian, Wirth, Thomas C.

“…BACKGROUND AND AIMS Programmed death 1 (PD‐1) checkpoint inhibition has shown promising results in patients with hepatocellular carcinoma, inducing objective…”
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