Search Results - "Wirapati, P."

The prognostic impact of consensus molecular subtypes (CMS) and its predictive effects for bevacizumab benefit in metastatic colorectal cancer: molecular analysis of the AGITG MAX clinical trial by Mooi, J.K., Wirapati, P., Asher, R., Lee, C.K., Savas, P., Price, T.J., Townsend, A., Hardingham, J., Buchanan, D., Williams, D., Tejpar, S., Mariadason, J.M., Tebbutt, N.C.

“…The consensus molecular subtypes (CMS) is a transcriptome-based classification of colorectal cancer (CRC) initially described in early-stage cohorts, but the…”
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Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial by Stintzing, S., Wirapati, P., Lenz, H.-J., Neureiter, D., Fischer von Weikersthal, L., Decker, T., Kiani, A., Kaiser, F., Al-Batran, S., Heintges, T., Lerchenmüller, C., Kahl, C., Seipelt, G., Kullmann, F., Moehler, M., Scheithauer, W., Held, S., Modest, D.P., Jung, A., Kirchner, T., Aderka, D., Tejpar, S., Heinemann, V.

“…FIRE-3 compared first-line therapy with FOLFIRI plus either cetuximab or bevacizumab in 592 KRAS exon 2 wild-type metastatic colorectal cancer (mCRC) patients…”
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Aflibercept efficacy according to sidedness, RAS and BRAF mutations. Findings from the VELOUR trial in second line therapy of advanced colorectal cancer patients by Maiello, E., Pomella, V., Wirapati, P., Di Bartolomeo, M., Zampino, M.G., Leone, F., Latiano, T.P., Pietrantonio, F., Ravenda, P.S., Marino, D., Tejpar, S.

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223 A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Iggo, R, Farmer, P, Wirapati, P, Anderle, P, Delorenzi, M, Bogaerts, J, Piccart, M, Cameron, D, Bergh, J, Bonnefoi, H

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A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Delorenzi, Mauro, Farmer, Pierre, Bonnefoi, Hervé, Anderle, Pascale, Cameron, David, Wirapati, Pratyakasha, Becette, Véronique, André, Sylvie, Piccart, Martine, Campone, Mario, Brain, Etienne, MacGrogan, Gaëtan, Petit, Thierry, Jassem, Jacek, Bibeau, Frédéric, Blot, Emmanuel, Bogaerts, Jan, Aguet, Michel, Bergh, Jonas, Iggo, Richard

“…Identifying factors that influence response to cancer chemotherapy is crucial for improving its efficacy. Mauro Delorenzi and his colleagues report that a…”
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Meiotic breakpoint mapping of a proposed X linked visual loss susceptibility locus in Leber's hereditary optic neuropathy by Handoko, H Y, Wirapati, P J, Sudoyo, H A, Sitepu, M, Marzuki, S

“…Leber's hereditary optic neuropathy (LHON) is a maternally inherited degenerative disorder characterised by an acute or subacute optic nerve degeneration…”
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Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis by Sotiriou, Christos, Wirapati, Pratyaksha, Loi, Sherene, Harris, Adrian, Fox, Steve, Smeds, Johanna, Nordgren, Hans, Farmer, Pierre, Praz, Viviane, Haibe-Kains, Benjamin, Desmedt, Christine, Larsimont, Denis, Cardoso, Fatima, Peterse, Hans, Nuyten, Dimitry, Buyse, Marc, Van de Vijver, Marc J., Bergh, Jonas, Piccart, Martine, Delorenzi, Mauro

“…Background: Histologic grade in breast cancer provides clinically important prognostic information. However, 30%–60% of tumors are classified as histologic…”
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Consensus molecular subtypes (cms) as predictors of benefit from bevacizumab in first line treatment of metastatic colorectal cancer: Retrospective analysis of the MAX clinical trial by Mooi, J., Wirapati, P., Asher, R., Lee, C., Savas, P., Price, T.J., Tejpar, S., Mariadason, J., Tebbutt, N.

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Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial by Stintzing, S, Wirapati, P, Lenz, H-J, Neureiter, D, Fischer von Weikersthal, L, Decker, T, Kiani, A, Kaiser, F, Al-Batran, S, Heintges, T, Lerchenmüller, C, Kahl, C, Seipelt, G, Kullmann, F, Moehler, M, Scheithauer, W, Held, S, Modest, D P, Jung, A, Kirchner, T, Aderka, D, Tejpar, S, Heinemann, V

“…FIRE-3 compared first-line therapy with FOLFIRI plus either cetuximab or bevacizumab in 592 KRAS exon 2 wild-type metastatic colorectal cancer (mCRC) patients…”
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Chromosomal number aberrations and transformation in adult mouse retinal stem cells in vitro by DJOJOSUBROTO, M, BOLLOTTE, F, WIRAPATI, P, RADTKE, F, STAMENKOVIC, I, ARSENIJEVIC, Y

“…Purpose The therapeutic potential of stem cells on degenerative diseases and damaged tissues such as retinal degeneration has been recognized. Generation of…”
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Biological mechanisms that trigger breast cancer (BC) tumor progression are molecular subtype dependent by Sotiriou, C., Desmedt, C., Haibe-Kains, B., Harris, A., Larsimont, D., Buyse, M., Wirapati, P., Delorenzi, M., Bontempi, G., Piccart, M.

“…Abstract only 10581 Background: We have recently developed several gene expression indices related to hallmarks of breast cancer involving various biological…”
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A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Farmer, P, Bonnefoi, H, Anderle, P, Cameron, D, Wirapati, P, Becette, V, Andre, S, Piccart, M, Campone, M, Brain, E, MacGrogan, G, Petit, T, Jassem, J, Bibeau, F, Blot, E, Bogaerts, J, Aguet, M, Bergh, J, Iggo, R, Delorenzi, M

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Different prediction of distant recurrence risk in primary breast cancer patients stratified by ER and ERBB2 status by Urban, P., Vuaroqueaux, V., Labuhn, M., Delorenzi, M., Wirapati, P., Dieterich, H., Ehret, S., Fürstenberger, G., Morant, R., Eppenberger, U., Eppenberger-Castori, S.

“…Abstract only 20120 Background: Molecular profiling recently defined biological characteristics of several long-recognized breast cancer subtypes including…”
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Comprehensive analysis integrating both clinicopathological and gene expression data in more than 1,500 samples: Proliferation captured by gene expression grade index appears to be the strongest prognostic factor in breast cancer (BC) by Sotiriou, C., Wirapati, P., Loi, S., Haibe-Kains, B., Desmedt, C., Tutt, A., Ellis, P., Buyse, M., Delorenzi, M., Piccart, M.

“…Abstract only 507 Background: Although, the development of high-throughput gene expression technologies has allowed the identification of several “molecular…”
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Molecular characterization of clinical grade in breast cancer (BC) challenges the existence of “grade 2” tumors by Sotiriou, C., Wirapati, P., Loi, S., Desmedt, C., Harris, A. L., Bergh, J., Smeds, J., Cardoso, F., Delorenzi, M., Piccart, M.

“…Abstract only…”
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A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Iggo, R, Farmer, P, Wirapati, P, Anderle, P, Delorenzi, M, Bogaerts, J, Piccart, M, Cameron, D, Bergh, J, Bonnefoi, H

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Gene expression profiling in breast cancer challenges the existence of intermediate histological grade by Sotiriou, C, Wirapati, P, Loi, S, Harris, A, Bergh, J, Smeds, J, Praz, V, Farmer, P, Haibe-Kains, B, Lallemand, F, Buyse, M, Piccart, M, Delorenzi, M

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Is genomic grading killing histological grading? by Sotiriou, C., Wirapati, P., Loi, S., Desmedt, C., Haibe-Kains, B., Piette, F., Buyse, M., Bontempi, G., Delorenzi, M., Piccart, M.

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A stroma-related gene signature predicts resistance to epirubicin-containing neoadjuvant chemotherapy in breast cancer by Farmer, P, Bonnefoi, H, Anderle, P, Cameron, D, Wirapati, P, Becatte, V, Andre, S, Piccart, M, Campone, M, Tabiana-Hulin, M, MacGrogan, G, Petit, T, Jassem, J, Rouanet, P, Blot, E, Bogaerts, J, Bergh, J, Iggc, R, Delorenzi, M

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Molecular characterization of clinical grade in breast cancer (BC) challenges the existence of "grade 2" tumors by Sotiriou, C, Wirapati, P, Loi, S, Desmedt, C, Harris, AL, Bergh, J, Smeds, J, Cardoso, F, Delorenzi, M, Piccart, M

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