Search Results - "Wirak, D"

Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice by Wirak, D. O., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

“…Alzheimer's disease is characterized by widespread deposition of amyloid in the central nervous system. The 4-kilodalton amyloid β protein is derived from a…”
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Regulatory region of human amyloid precursor protein (APP) gene promotes neuron‐specific gene expression in the CNS of transgenic mice by Wirak, D. O., Bayney, R., Kundel, C. A., Lee, A., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

“…The accumulation of beta‐amyloid protein in specific brain regions is a central pathological feature of Alzheimer's disease (AD). The 4 kd beta‐amyloid protein…”
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In the absence of a downstream element, the apolipoprotein E gene is expressed at high levels in kidneys of transgenic mice by SIMONET, W. S, BUCAY, N, LAUER, S. J, WIRAK, D. O, STEVENS, M. E, WEISGRABER, K. H, PITAS, R. E, TAYLOR, J. M

“…Human apolipoprotein (apo) E gene constructs with 30 or 5 kilobases of 5'-flanking and 1.5 kilobases of 3'-flanking regions were used to create transgenic…”
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Microinjecting DNA into mouse ova to study DNA replication and gene expression and to produce transgenic animals by DePamphilis, M L, Herman, S A, Martínez-Salas, E, Chalifour, L E, Wirak, D O, Cupo, D Y, Miranda, M

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Age-Associated Inclusions in Normal and Transgenic Mouse Brain by Jucker, Mathias, Walker, Lary C., Martin, Lee J., Kitt, Cheryl A., Kleinman, Hynda K., Ingram, Donald K., Price, Donald L., Wirak, D., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

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Expression of simian virus 40 early and late genes in mouse oocytes and embryos by CHALIFOUR, L. E, WIRAK, D. O, WASSARMAN, P. M, DEPAMPHILIS, M. L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sequence-dependent DNA replication in preimplantation mouse embryos by Wirak, D O, Chalifour, L E, Wassarman, P M, Muller, W J, Hassell, J A, DePamphilis, M L

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Effect of bacteriophage T4 DNA topoisomerase gene 39 on level of beta chain of ribonucleoside diphosphate reductase in a T4 nrdB mutant by Cook, K S, Wirak, D O, Seasholtz, A F, Greenberg, G R

“…Bacteriophage T4 ribonucleoside diphosphate reductase consists of alpha 2 and beta 2 subunits encoded by genes nrdA and nrdB, respectively, and plays a central…”
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cis- and trans-acting sequences required for expression of simian virus 40 genes in mouse oocytes by Chalifour, L E, Wirak, D O, Hansen, U, Wassarman, P M, DePamphilis, M L

“…To determine the requirements for gene expression in mammalian germ cells, circular double-stranded simian virus 40 (SV40) DNA molecules containing deletions…”
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Defect in synthesis of deoxyribonucleotides by a bacteriophage T4 nrdB mutant is suppressed on mutation of T4 DNA topoisomerase gene by Wirak, D O, Cook, K S, Greenberg, G R

“…Bacteriophage T4 infection is known to induce the formation of a complex of enzymes effecting the de novo synthesis of deoxyribonucleoside triphosphates, which…”
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Transgenic mice and transhybridomas producing chimeric mouse/human anti-human interleukin-2 receptor recombinant antibodies by Cahill, K B, Wirak, D O, Mierz, D V, Wunderlich, D A, Rose, B W, Shedd, D G, Gillespie, A, Zerler, B R

“…Transgenic mice were developed that secreted chimeric mouse/human anti-human interleukin-2 receptor (IL-2R) antibodies (Ab) into their serum. In addition,…”
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Response : Age-Associated Inclusions in Normal and Transgenic Mouse Brain by Wirak, D., Bayney, R., Ramabhadran, T. V., Fracasso, R. P., Hart, J. T., Hauer, P. E., Hsiau, P., Pekar, S. K., Scangos, G. A., Trapp, B. D., Unterbeck, A. J.

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Role of bacteriophage T4 DNA-delay gene products in deoxyribonucleotide synthesis by Wirak, D O, Greenberg, G R

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Processing of the Pre‐β‐amyloid Protein by Cathepsin d is Enhanced by a Familial Alzheimer's Disease Mutation by Dreyer, Robert N., Bausch, Kathryn M., Fracasso, Paul, Hammond, Lisa J., Wunderlich, David, Wirak, Dana O., Davis, Gary, Brini, Carla M., Buckholz, Thomas M., König, Gerhard, Kamarck, Michael E., Tamburini, Paul P.

“…A major pre‐β‐amyloid protein695 (APP695) processing activity from Alzheimer's disease brain extracts was identified and found to be indistinguishable from the…”
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Remodelling of lipoproteins in transgenic mice expressing human cholesteryl ester transfer protein by Dinchuk, Joseph, Hart, John, Gonzalez, Genevieve, Karmann, Guenther, Schmidt, Delf, Wirak, Dana O.

“…Cholesteryl ester transfer protein (CETP) facilitates the transfer of reciprocal exchange of neutral lipids between lipoproteins. To better understand the…”
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Deposits of Amyloid (Beta) Protein in the Central Nervous System of Transgenic Mice by Wirak, D O, Bayney, R

“…Alzheimer's disease is characterized by widespread deposition of amyloid in the central nervous system. Transgenic mice expressing amyloid beta protein in the…”
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Defect in synthesis of deoxyribonucleotides by a bacteriophage T4 nrdM mutant is suppressed on mutation of T4 DNA topoisomerase gene by WIRAK, D. O, COOK, K. S, GREENBERG, G. R

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Age-associated inclusions in normal and transgenic mouse brain by Wirak, D, Bayney, R, Ramabhadran, T V, Fracasso, R P, Hart, J T, Hauer, P E, Hsiau, P, Pekar, S K, Scangos, G A, Trapp, B D, Unterbeck, A J

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Deposits of amyloid B protein in the central nervous system of transgenic mice by WIRAK, D. O, BAYNEY, R, UNTERBECK, A. J, RAMABHADRAN, T. V, FRACASSO, R. P, HART, J. T, HAUER, P. E, HSIAU, P, PEKAR, S. K, SCANGOS, G. A, TRAPP, B. D

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Defect in synthesis of deoxyribonucleotides by a bacteriophage T4 nrdBmutant is suppressed on mutation of T4 DNA topoisomerase gene by Wirak, DO, Cook, K S, Greenberg, G R

“…The nrdB93 mutation had a profound effect on deoxyribonucleotide synthesis at 41 degree C; even at the permissive temperature of 30 degree C, synthesis was…”
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