Search Results - "Wira, CR"

Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: stratification and integration of immune protection against the transmission of sexually transmitted infections by Hickey, D.K, Patel, M.V, Fahey, J.V, Wira, C.R

“…Abstract This review examines the multiple levels of pre-existing immunity in the upper and lower female reproductive tract. In addition, we highlight the need…”
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Innate and adaptive immunity in female genital tract: cellular responses and interactions by Wira, Charles R., Fahey, John V., Sentman, Charles L., Pioli, Patricia A., Shen, Li

“…The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the unique requirements of dealing with sexually transmitted bacterial and…”
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Innate Immunity in the Human Female Reproductive Tract: Antiviral Response of Uterine Epithelial Cells to the TLR3 Agonist Poly(I:C) by Schaefer, Todd M, Fahey, John V, Wright, Jacqueline A, Wira, Charles R

“…The objective of this study was to examine the expression of TLR by human primary uterine epithelial cells (UEC) and to determine whether exposure to the TLR…”
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Toll‐like receptor (TLR) expression and TLR‐mediated cytokine/chemokine production by human uterine epithelial cells by Schaefer, Todd M., Desouza, Kristin, Fahey, John V., Beagley, Kenneth W., Wira, Charles R.

“…Summary The objective of this study was to examine the expression of toll‐like receptors (TLRs) by the uterine epithelial cell line ECC‐1 and to determine if…”
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Differential Expression of Toll-Like Receptors 2 and 4 in Tissues of the Human Female Reproductive Tract by PIOLI, Patricia A, AMIEL, Eyal, SCHAEFER, Todd M, CONNOLLY, John E, WIRA, Charles R, GUYRE, Paul M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Epithelial Cells in the Female Reproductive Tract: a Central Role as Sentinels of Immune Protection by Wira, Charles R., Grant-Tschudy, Katherine S., Crane-Godreau, Margaret A.

“…The continued presence of bacterial and viral antigens in the lumen of the vagina coupled with the periodic presence of antigens in the lumena of the upper…”
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Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract by Fahey, J.V., Schaefer, T.M, Channon, J.Y., Wira, C.R.

“…BACKGROUND: Pro-inflammatory chemokines that attract and cytokines that activate immune cells contribute to normal physiological homeostasis in the female…”
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Recruitment of Uterine NK Cells: Induction of CXC Chemokine Ligands 10 and 11 in Human Endometrium by Estradiol and Progesterone by Sentman, Charles L, Meadows, Sarah K, Wira, Charles R, Eriksson, Mikael

“…Uterine NK (uNK) cells express a unique set of markers compared with blood NK cells. However, recent studies suggest that uNK cells may be derived from the…”
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Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture by Fahey, J V, Wright, J A, Shen, L, Smith, J M, Ghosh, M, Rossoll, R M, Wira, C R

“…The goal of this study was to examine the role of E 2 in regulating innate immune protection by human uterine epithelial cells (UECs). Recognizing that UECs…”
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Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-β by Eriksson, Mikael, Meadows, Sarah K., Wira, Charles R., Sentman, Charles L.

“…Natural killer (NK) cells are a major population of lymphocytes in the human endometrium (EM), and NK cells can be a significant source of cytokines that alter…”
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Epithelial cell secretions from the human female reproductive tract inhibit sexually transmitted pathogens and Candida albicans but not Lactobacillus by Wira, C R, Ghosh, M, Smith, J M, Shen, L, Connor, R I, Sundstrom, P, Frechette, G M, Hill, E T, Fahey, J V

“…Female reproductive tract (FRT) epithelial cells protect against potential pathogens and sexually transmitted infections. The purpose of this study was to…”
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Estrogen Receptor α Antagonists Mediate Changes in CCL20 and CXCL1 Secretions in the Murine Female Reproductive Tract by Hickey, Danica K., Fahey, John V., Wira, Charles R.

“…Problem Estradiol regulates chemokine secretion from uterine epithelial cells, but little is known about estradiol regulation in vivo or the role of estrogen…”
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The innate immune system: gatekeeper to the female reproductive tract by Wira, Charles R., Fahey, John V.

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Effect of mouse uterine stromal cells on epithelial cell transepithelial resistance (TER) and TNFα and TGFβ release in culture by GRANT, Katherine S, WIRA, Charles R

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IL-1β-Mediated Proinflammatory Responses Are Inhibited by Estradiol via Down-Regulation of IL-1 Receptor Type I in Uterine Epithelial Cells by Schaefer, Todd M, Wright, Jacqueline A., Pioli, Patricia A., Wira, Charles R.

“…The objective of this study was to examine the effects of sex hormones on IL-1β-mediated responses by uterine epithelial cells. The mRNA expression and…”
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Effect of Menstrual Status on Antibacterial Activity and Secretory Leukocyte Protease Inhibitor Production by Human Uterine Epithelial Cells in Culture by Fahey, John V., Wira, Charles R.

“…The objective of this study was to examine the production of antibacterial factor(s) by uterine epithelial cells from pre- and postmenopausal women. Apical…”
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Effects of Estradiol and Progesterone on Susceptibility and Early Immune Responses to Chlamydia trachomatis Infection in the Female Reproductive Tract by KAUSHIC, C, FAN ZHOU, MURDIN, A. D, WIRA, C. R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Chemokine receptor expression in the human ectocervix: implications for infection by the human immunodeficiency virus‐type I by Yeaman, Grant R., Asin, Susana, Weldon, Sally, Demian, Douglas J., Collins, Jane E., Gonzalez, Jorge L., Wira, Charles R., Fanger, Michael W., Howell, Alexandra L.

“…Summary Human immunodeficiency virus‐type 1 (HIV‐1) is a sexually transmitted pathogen that can infect cells in the female reproductive tract (FRT). The…”
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Antigen-presenting cells in the female reproductive tract: influence of estradiol on antigen presentation by vaginal cells by Wira, C R, Rossoll, R M, Kaushic, C

“…The objective of the present study was to define the afferent arm of the mucosal immune system in the lower female reproductive tract. We report here that…”
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Secretion of monocyte chemotactic protein-1 by human uterine epithelium directs monocyte migration in culture by Meter, Richard A, Wira, Charles R, Fahey, John V

“…To determine whether primary human uterine epithelial cells in culture are able to influence monocyte chemotaxis and to establish whether the causal agent of…”
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