Search Results - "Winters, M A"

Relationship between clinical outcomes and Dutch frailty score among elderly patients who underwent surgery for hip fracture by Winters, A M, Hartog, L C, Roijen, Hif, Brohet, R M, Kamper, A M

“…Frailty is a geriatric condition that is associated with an increased risk of mortality and functional decline. To date, mainly the Groningen Frailty Indicator…”
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Dried-Plasma Transport Using a Novel Matrix and Collection System for Human Immunodeficiency Virus and Hepatitis C Virus Virologic Testing by Lloyd, R.M. Jr, Burns, D.A, Huong, J.T, Mathis, R.L, Winters, M.A, Tanner, M, De La Rosa, A, Yen-Lieberman, B, Armstrong, W, Taege, A, McClernon, D.R, Wetshtein, J.L, Friedrich, Brian M, Ferguson, Monique R, O'Brien, William, Feorino, P.M, Holodniy, M

“…A novel method for the collection and transportation of dried-blood-plasma samples, SampleTanker (ST), was developed and compared to standard shipping…”
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Restructuring the neuronal stress response with anti-glucocorticoid gene delivery by Kaufer, D, Ogle, W O, Pincus, Z S, Clark, K L, Nicholas, A C, Dinkel, K M, Dumas, T C, Ferguson, D, Lee, A L, Winters, M A, Sapolsky, R M

“…Glucocorticoids, the adrenal steroids released during stress, compromise the ability of neurons to survive neurological injury. In contrast, estrogen protects…”
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Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years by WINTERS, M. A, SHAFER, R. W, JELLINGER, R. A, MAMTORA, G, GINGERAS, T, MERIGAN, T. C

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Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis by GOERING, R. V, WINTERS, M. A

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A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors by Winters, M A, Coolley, K L, Girard, Y A, Levee, D J, Hamdan, H, Shafer, R W, Katzenstein, D A, Merigan, T C

“…While many point mutations in the HIV-1 reverse transcriptase (RT) confer resistance to antiretroviral drugs, inserts or deletions in this gene have not been…”
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The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients by SCHAPIRO, J. M, WINTERS, M. A, STEWART, F, EFRON, B, NORRIS, J, KOZAL, M. J, MERIGAN, T. C

“…To evaluate the efficacy and safety of high-dose therapy with the human immunodeficiency virus (HIV) protease inhibitor saquinavir and to establish the…”
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Multiple concurrent Reverse transcriptase and protease mutations and multidrug resistance of HIV-1 Isolates from heavily treated patients by SHAFER, R. W, WINTERS, M. A, PALMER, S, MERIGAN, T. C

“…Drug resistance of HIV-1 is an obstacle to the long-term efficacy of antiretroviral therapy. To characterize reverse transcriptase and protease genes of…”
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Prognostic value of Geriatric-8 for adverse outcomes within 30 days of surgery in older adults with colorectal cancer: A retrospective cohort study by Winters, A.M., Bakker, J., ten Hoor, J., Bilo, H.J.G., Roodbol, P.F., Edens, M.A., Finnema, E.J.

“…It is unclear whether the Geriatric-8 (G8) has the accuracy to preselect patients for complete geriatric assessment, and has the ability to predict adverse…”
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Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy by Iversen, A K, Shafer, R W, Wehrly, K, Winters, M A, Mullins, J I, Chesebro, B, Merigan, T C

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Combination Therapy with Zidovudine and Didanosine Selects for Drug-Resistant Human Immunodeficiency Virus Type 1 Strains with Unique Patterns of pol Gene Mutations by Shafer, Robert W., Kozal, Michael J., Winters, Mark A., Iversen, Astrid K. N., Katzenstein, David A., Ragni, Margaret V., Meyer, William A., Gupta, Phalquni, Rasheed, Suraiya, Coombs, Robert, Katzman, Michael, Fiscus, Susan, Merigan, Thomas C.

“…Drug resistance conferred by specific human immunodeficiency virus type 1 (HIV-1) pol gene mutations has been associated with clinical progression in…”
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Precipitation of proteins in supercritical carbon dioxide by Winters, M A, Knutson, B L, Debenedetti, P G, Sparks, H G, Przybycien, T M, Stevenson, C L, Prestrelski, S J

“…Supercritical CO2 was used as an antisolvent to form protein particles that exhibited minimal loss of activity upon reconstitution. Organic protein solutions…”
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Human Immunodeficiency Virus Type 1 Protease Genotypes and In Vitro Protease Inhibitor Susceptibilities of Isolates from Individuals Who Were Switched to Other Protease Inhibitors after Long-Term Saquinavir Treatment by Winters, M A, Schapiro, J M, Lawrence, J, Merigan, T C

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Drug Resistance and Heterogeneous Long-Term Virologic Responses of Human Immunodeficiency Virus Type 1-Infected Subjects to Zidovudine and Didanosine Combination Therapy by Shafer, Robert W., Iversen, Astrid K. N., Winters, Mark A., Aguiniga, Elsa, Katzenstein, David A., Merigan, Thomas C.

“…Plasma human immunodeficiency virus (HIV) type 1 RNA levels, CD4 lymphocyte changes, and drug resistance were studied in HIV-infected patients with 200–500 CD4…”
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Association Between Orthostatic Hypotension and Handgrip Strength With Successful Rehabilitation in Elderly Hip Fracture Patients by Hartog, L.C., MD, MSc, Winters, A.M., MSc, Roijen, H., MD, MSc, Kamper, A.M., MD, PhD, Inia, H., MD, MSc, Kleefstra, N., MD, PhD, Bilo, H.J.G., MD, PhD, van Hateren, K.J.J., MD, PhD

“…Abstract Objective To investigate the relationship between orthostatic hypotension (OH) and muscle strength versus time to successful rehabilitation within…”
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Changes in CD4+ and CD8+ T cell subsets in response to highly active antiretroviral therapy in HIV type 1-infected patients with prior protease inhibitor experience by Gray, C M, Schapiro, J M, Winters, M A, Merigan, T C

“…This study explores whether previous failures on antiretroviral drug regimens preclude the possibility of immune restoration. This was assessed by evaluating T…”
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Biological variation and quality control of plasma human immunodeficiency virus type 1 RNA quantitation by reverse transcriptase polymerase chain reaction by WINTERS, M. A, TAN, L. B, KATZENSTEIN, D. A, MERIGAN, T. C

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A Mutation in Human Immunodeficiency Virus Reverse Transcriptase and Decline in CD4 Lymphocyte Numbers in Long-Term Zidovudine Recipients by Kozal, Michael J., Shafer, Robert W., Winters, Mark A., Katzenstein, David A., Merigan, Thomas C.

“…A nested polymerase chain reaction assay was used to define the sequence of a specific codon, amino acid 215, of the human immunodeficiency virus (HIV) pol…”
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Functional Correlates of Insertion Mutations in the Protease Gene of Human Immunodeficiency Virus Type 1 Isolates from Patients by Kim, E Y, Winters, M A, Kagan, R M, Merigan, T C

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Comparison of QIAamp HCV kit spin columns, silica beads, and phenol-chloroform for recovering human immunodeficiency virus type 1 RNA from plasma by SHAFER, R. W, LEVEE, D. J, WINTERS, M. A, RICHMOND, K. L, HUANG, D, MERIGAN, T. C

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