Search Results - "Winter, Des C."

Molecular Pathways: The Role of NR4A Orphan Nuclear Receptors in Cancer by MOHAN, Helen M, AHERNE, Carol M, ROGERS, Ailin C, BAIRD, Alan W, WINTER, Des C, MURPHY, Evelyn P

“…Nuclear receptors are of integral importance in carcinogenesis. Manipulation of classic ligand-activated nuclear receptors, such as estrogen receptor blockade…”
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Extended right colectomy, left colectomy, or segmental left colectomy for splenic flexure carcinomas: a European multicenter propensity score matching analysis by de’Angelis, Nicola, Martínez-Pérez, Aleix, Winter, Des C., Landi, Filippo, Vitali, Giulio Cesare, Le Roy, Bertrand, Coccolini, Federico, Brunetti, Francesco, Celentano, Valerio, Di Saverio, Salomone, Ris, Frederic, Fuks, David, Espin, Eloy

“…Background The surgical resection of the splenic flexure carcinoma (SFC) is challenging and the optimal surgical procedure for SFCs remains a matter of debate…”
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Radiofrequency Ablation for Neuroendocrine Liver Metastases: A Systematic Review by Mohan, Helen, MRCSI, Nicholson, Patrick, MRCSI, Winter, Des C., MD, O’Shea, Donal, MD, O’Toole, Dermot, MD, Geoghegan, Justin, FRCSI, Maguire, Donal, FRCSI, Hoti, Emir, FRCSEd, Traynor, Oscar, FRCSI, Cantwell, Colin P., MD

“…Abstract To determine the efficacy of radiofrequency (RF) ablation in neuroendocrine tumor (NET) liver metastases. A systematic review was performed following…”
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A meta-analysis of carbon dioxide versus room air insufflation on patient comfort and key performance indicators at colonoscopy by Rogers, Ailín C, Van De Hoef, Dayna, Sahebally, Shaheel M, Winter, Des C

“…Background Carbon dioxide (CO 2 ) has been used as an alternative to air insufflation at endoscopy with good results; however, uptake of the technique has been…”
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The Role of Organoids as a Novel Platform for Modeling of Inflammatory Bowel Disease by O'Connell, Lauren, Winter, Des C, Aherne, Carol M

“…Inflammatory bowel disease (IBD) is a chronic relapsing-remitting immune-mediated disorder affecting the gut. It is common in Westernized regions and is…”
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An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases by Reynolds, Ian S, Cromwell, Paul M, Ryan, Éanna J, McGrath, Erinn, Kennelly, Rory, Ryan, Ronan, Swan, Niall, Sheahan, Kieran, Winter, Des C, Hoti, Emir

“…Mucinous colorectal cancer has traditionally been associated with high rates of recurrence and poor long-term survival. There is limited published data on…”
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Sphincter preservation for distal rectal cancer - a goal worth achieving at all costs by Mulsow, Jürgen, Winter, Des C

“…To assess the merits of currently available treatment options in the management of patients with low rectal cancer, a review of the medical literature…”
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Electrochemotherapy for colorectal cancer using endoscopic electroporation: a phase 1 clinical study by Falk Hansen, Hanne, Bourke, Michael, Stigaard, Trine, Clover, James, Buckley, Martin, O’Riordain, Micheal, Winter, Des C., Hjorth Johannesen, Helle, Hansen, Rasmus Hvass, Heebøll, Hanne, Forde, Patrick, Jakobsen, Henrik Loft, Larsen, Ole, Rosenberg, Jacob, Soden, Declan, Gehl, Julie

“…Abstract Background and study aims Electrochemotherapy is an anticancer treatment that uses electric pulses to facilitate uptake of chemotherapeutic drugs in…”
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Emergency surgery for splenic flexure cancer: results of the SFC Study Group database by de'Angelis, Nicola, Espin, Eloy, Ris, Frederic, Landi, Filippo, Le Roy, Bertrand, Coccolini, Federico, Celentano, Valerio, Gurrado, Angela, Pezet, Denis, Bianchi, Giorgio, Memeo, Riccardo, Vitali, Giulio C, Solis, Alejandro, Denet, Christine, Di Saverio, Salomone, de'Angelis, Gian Luigi, Kraft, Miquel, Gonzálvez-Guardiola, Paula, Stakelum, Aine, Catena, Fausto, Fuks, David, Winter, Des C, Testini, Mario, Martínez-Pérez, Aleix

“…The effectiveness of surgical treatment for splenic flexure carcinomas (SFCs) in emergency settings remains unexplored. This study aims to compare the…”
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Practical Guide to Clinical Trial Publication by Winter, Des C, Haukoos, Jason, Salminen, Paulina

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The therapeutic and prognostic implications of immunobiology in colorectal cancer: a review by Zaborowski, Alexandra M., Winter, Des C., Lynch, Lydia

“…Colorectal cancer represents the second leading cause of cancer-related death worldwide. The therapeutic field of immuno-oncology has rapidly gained momentum,…”
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Organoids: Past Learning and Future Directions by O'Connell, Lauren, Winter, Des C

“…Preclinical medical research has historically depended on either traditional two-dimensional in vitro cell culture or animal models for the purposes of disease…”
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Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1 by Dunne, Margaret R, Ryan, Ciara, Nolan, Bláthnaid, Tosetto, Miriam, Geraghty, Robert, Winter, Des C, O'Connell, P Ronan, Hyland, John M, Doherty, Glen A, Sheahan, Kieran, Ryan, Elizabeth J, Fletcher, Jean M

“…T cell infiltration into colorectal tumors has been shown to correlate with improved patient outcomes. However, more detailed information on the makeup and…”
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Concise Commentary: Pocketing the Difference—Genetics and the Changing Paradigms of Diverticulitis Management by Winter, Des C.

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Biological fate and clinical implications of arginine metabolism in tissue healing by Curran, John N., Winter, Des C., Bouchier-Hayes, David

“…ABSTRACT Since its discovery in 1987, many biological roles (including wound healing) have been identified for nitric oxide (NO). The gas is produced by NO…”
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Author response to: Comment on: Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of randomized clinical trials by Donnelly, Mark, Ryan, Odhrán K, Ryan, Éanna J, Winter, Des C

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Art and science: complementary in medicine? by MacKay, Graham J, Winter, Des C

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Art and science: complementary in medicine? by MacKay, Graham J, Winter, Des C

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Colonoscopic tattooing: ready, steady, glow by Lynch, Noel P, Winter, Des C

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Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study by Fernandez, Laura M, São Julião, Guilherme P, Figueiredo, Nuno L, Beets, Geerard L, van der Valk, Maxime J M, Bahadoer, Renu R, Hilling, Denise E, Meershoek-Klein Kranenbarg, Elma, Roodvoets, Annet G H, Renehan, Andrew G, van de Velde, Cornelis J H, Habr-Gama, Angelita, Perez, Rodrigo O, Abdelrazeq, A., Asoglu, Oktar, Barroca, Rita, Beveridge, J., Bhowmick, A., Blower, A., Braun, M., Bujko, Krzysztof, Carter, P., Carvalho, Carlos, Coco, Claudio, Cunningham, Chris, D’Hoore, André, Dimofte, Gabriel, Ding, Peirong, Duff, S., Dwyer, S.T., Epstein, J., Evans, D., Fulford, P., Gaertner, Wolfgang, Gerard, Jean-Pierre, Gollins, Simon, Harris, R., Harrison, J., Heat, J., Hill, J., Hobbiss, J., Huertas, Eduardo, Huq, Z., Iseas, Soledad, Jakobsen, Anders, Jones, D., Jones, L., Khan, U., Kushwaha, R., Lees, N., Linn, T.Y., Loganathan, S., López Campos, Fernando, Madoff, Robert, Mamedli, Zaman Z., Martling, Anna, Matzel, Klaus E., Melenhorst, Jarno, Mitchell, P., Murad-Regadas, Sthela M., O'Dwyer, Sarah T., Pairola, Alejandro, Paraoan, M., Pares, Oriol, Peeters, Koen C.M.J., Pettit, S.H., Pranesh, N., Rajaganeshan, R., Ravi, S., Rawat, S., Richards, D., Riyad, K., Rossi, Gustavo, Rutten, Harm J.T., Saeed, M., Salaman, J., Sanchez Loria, Fernando, Van der Sande, Marit E., Santiago, Ines, Selvasekar, C., Siddiqui, K.H., Smart, C., Solkar, M.H., Sun Myint, Arthur, Taylor, B., Telford, K., Scott, Nigel, Vaccaro, Carlos A., Vailati, Bruna B., Verberne, Charlotte, Vieira, Pedro, Vimalchandran, D., Ward, S., Wilson, M.S., Winter, Des C., Witjes, Carlijn, Wolthuis, Albert M., Zhang, Jing, Zhang, Zhen

“…Watch and wait is a novel management strategy in patients with rectal cancer who have a clinical complete response after neoadjuvant chemoradiotherapy…”
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