Search Results - "Winter, C. L"

Natural disease history of mouse models for limb girdle muscular dystrophy types 2D and 2F by Pasteuning-Vuhman, S, Putker, K, Tanganyika-de Winter, C L, Boertje-van der Meulen, J W, van Vliet, L, Overzier, M, Plomp, J J, Aartsma-Rus, A, van Putten, M

“…Limb-girdle muscular dystrophy types 2D and 2F (LGMD 2D and 2F) are autosomal recessive disorders caused by mutations in the alpha- and delta sarcoglycan…”
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Scalable statistics of correlated random variables and extremes applied to deep borehole porosities by Guadagnini, A, Neuman, S. P, Nan, T, Riva, M, Winter, C. L

“…We analyze scale-dependent statistics of correlated random hydrogeological variables and their extremes using neutron porosity data from six deep boreholes, in…”
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Nonlinear effects of locally heterogeneous hydraulic conductivity fields on regional stream–aquifer exchanges by Zhu, J, Winter, C L, Wang, Z

“…Computational experiments are performed to evaluate the effects of locally heterogeneous conductivity fields on regional exchanges of water between stream and…”
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A reduced complexity model for probabilistic risk assessment of groundwater contamination by Winter, C. L., Tartakovsky, Daniel M.

“…We present a model of reduced complexity for assessing the risk of groundwater pollution from a point source. The progress of contamination is represented as a…”
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Forecasting skill of model averages by Winter, C. L., Nychka, Doug

“…Given a collection of science-based computational models that all estimate states of the same environmental system, we compare the forecast skill of the…”
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Uncertain Future of Hydrogeology by Tartakovsky, Daniel M, Winter, C. L

“…Many of hydrogeology’s most fundamental questions remain unresolved today, a hundred years after the basic governing equations for groundwater flow and…”
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Natural disease history of the dy2J mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy by Pasteuning-Vuhman, S, Putker, K, Tanganyika-de Winter, C L, Boertje-van der Meulen, J W, van Vliet, L, Overzier, M, Plomp, J J, Aartsma-Rus, A, van Putten, M

“…Merosin deficient congenital muscular dystrophy 1A (MDC1A) is a very rare autosomal recessive disorder caused by mutations in the LAMA2 gene leading to severe…”
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Groundwater flow in heterogeneous composite aquifers by Winter, C. L., Tartakovsky, Daniel M.

“…We introduce a stochastic model of flow through highly heterogeneous, composite porous media that greatly improves estimates of pressure head statistics…”
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Two-scale analytical homogenization of Richards' equation for flows through block inclusions by Sviercoski, R.F, Warrick, A.W, Winter, C.L

“…In this paper we propose an analytical form for the upscaled coefficient applicable to the nonlinear Richards' equation. Block inclusions are symmetrically…”
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Intermittent versus continuous stretching effects on osteoblast-like cells in vitro by Winter, L. C., Walboomers, X. F., Bumgardner, J. D., Jansen, J. A.

“…The objective of this study was to quantify and compare stretch‐mediated responses of primary rat osteoblast‐like cells to uniform cyclic strain applied…”
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Normalized Mahalanobis distance for comparing process-based stochastic models by Winter, C. L.

“…We investigate a method based on normalized Mahalanobis distance, D , for comparing the performance of alternate stochastic models of a given environmental…”
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Multivariate sensitivity analysis of saturated flow through simulated highly heterogeneous groundwater aquifers by Winter, C.L., Guadagnini, A., Nychka, D., Tartakovsky, D.M.

“…A multivariate Analysis of Variance (ANOVA) is used to measure the relative sensitivity of groundwater flow to two factors that indicate different dimensions…”
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Moment differential equations for flow in highly heterogeneous porous media by WINTER, C. L, TARTAKOVSKY, D. M, GUADAGNINI, A

“…Quantitative descriptions of flow and transport in subsurface environmentsare often hampered by uncertainty in the input parameters. Treatingsuch parameters as…”
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Therapeutic Modulation of DMD Splicing by Blocking Exonic Splicing Enhancer Sites with Antisense Oligonucleotides by AARTSMA-RUS, A., JANSON, A.A.M., HEEMSKERK, J.A., DE WINTER, C.L., VAN OMMEN, G.-J.B., VAN DEUTEKOM, J.C.T.

“…:  Antisense oligonucleotides (AONs) can be used to correct the disrupted reading frame of Duchenne muscular dystophy patients (DMD). We have a collection of…”
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Mean Flow in composite porous media by Winter, C. L., Tartakovsky, Daniel M.

“…We develop probabilities and statistics for the parameters of Darcy flows through saturated porous media composed of units of different materials. Our…”
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Stochastic hydrology: practical alternatives exist by Winter, C. L.

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Stretch-mediated responses of osteoblast-like cells cultured on titanium-coated substrates in vitro by Walboomers, X. F., Habraken, W. J. E. M., Feddes, B., Winter, L. C., Bumgardner, J. D., Jansen, J. A.

“…Cyclic stretching experiments on osteoblast‐like cells have proven to be a useful tool in understanding the underlying mechanisms of load transduction at the…”
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Numerical solutions of moment equations for flow in heterogeneous composite aquifers by Winter, C. L., Tartakovsky, Daniel M., Guadagnini, Alberto

“…We analyze flow in heterogeneous media composed of multiple materials whose hydraulic properties and geometries are uncertain. Our analysis relies on the…”
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Random domain decomposition for flow in heterogeneous stratified aquifers by Guadagnini, A, Guadagnini, L, Tartakovsky, D M, Winter, C L

“…We study two-dimensional flow in a layered heterogeneous medium composed of two materials whose hydraulic properties and spatial distribution are known…”
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Direct numerical simulation of fully saturated flow in natural porous media at the pore scale: a comparison of three computational systems by Siena, M., Hyman, J. D., Riva, M., Guadagnini, A., Winter, C. L., Smolarkiewicz, P. K., Gouze, P., Sadhukhan, S., Inzoli, F., Guédon, G., Colombo, E.

“…Direct numerical simulations of flow through two millimeter-scale rock samples of limestone and sandstone are performed using three diverse fluid dynamic…”
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