Search Results - "Winsvold, Bendik S"
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Genome‐Wide Association Study Identifies Risk Loci for Cluster Headache
Published in Annals of neurology (01-08-2021)“…Objective This study was undertaken to identify susceptibility loci for cluster headache and obtain insights into relevant disease pathways. Methods We carried…”
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Rare variant analyses in large-scale cohorts identified SLC13A1 associated with chronic pain
Published in Pain (Amsterdam) (01-08-2023)“…Chronic pain is a prevalent disease with increasing clinical challenges. Genome-wide association studies in chronic pain patients have identified hundreds of…”
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Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache
Published in Annals of neurology (01-08-2021)“…Objective Identifying common genetic variants that confer genetic risk for cluster headache. Methods We conducted a case–control study in the Dutch Leiden…”
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Genetic variation in P2RX7 and pain tolerance
Published in Pain (Amsterdam) (01-06-2018)“…P2X7 is a nonselective cation channel activated by extracellular ATP. P2X7 activation contributes to the proinflammatory response to injury or bacterial…”
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Brain-specific genes contribute to chronic but not to acute back pain
Published in Pain reports (01-09-2022)“…Back pain is the leading cause of disability worldwide. Although most back pain cases are acute, 20% of acute pain patients experience chronic back pain…”
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Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci
Published in Frontiers in neurology (17-12-2021)“…About one third of patients with chronic polyneuropathy have no obvious underlying etiology and are classified as having idiopathic polyneuropathy. The lack of…”
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The effect of foetal growth restriction on the development of migraine and tension-type headache in adulthood. The HUNT Study
Published in PloS one (14-04-2017)“…There is little knowledge about how factors early in life affect the development of migraine and tension-type headache. We aimed to examine whether growth…”
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Epigenetic DNA methylation changes associated with headache chronification: A retrospective case-control study
Published in Cephalalgia (01-02-2018)“…Background The biological mechanisms of headache chronification are poorly understood. We aimed to identify changes in DNA methylation associated with the…”
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The current state of cluster headache genetics
Published in Headache (01-07-2021)Get full text
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Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes
Published in Nature communications (13-08-2019)“…Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated with substantial functional deficits. Here, we identify 42 loci for…”
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Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Published in Biological psychiatry (1969) (15-08-2016)“…Abstract Background Why schizophrenia has accompanied humans throughout our history despite its negative effect on fitness remains an evolutionary enigma. It…”
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Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Published in Brain (London, England : 1878) (29-04-2022)“…Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions. Whether chronic overlapping pain conditions…”
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Sex- and age-specific genetic analysis of chronic back pain
Published in Pain (Amsterdam) (01-04-2021)“…Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity, and poorer response to treatment…”
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HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study
Published in Scientific reports (27-05-2024)“…Statins are thought to have positive effects on migraine but existing data are inconclusive. We aimed to evaluate the causal effect of such drugs on migraines…”
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A causal effects of gut microbiota in the development of migraine
Published in Journal of headache and pain (17-07-2023)“…Background The causal association between the gut microbiome and the development of migraine and its subtypes remains unclear. Methods The single nucleotide…”
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Gene-based pleiotropy across migraine with aura and migraine without aura patient groups
Published in Cephalalgia (01-06-2016)“…It is unclear whether patients diagnosed according to International Classification of Headache Disorders criteria for migraine with aura (MA) and migraine…”
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Chronic musculoskeletal complaints as a predictor of mortality—The HUNT study
Published in Pain (Amsterdam) (01-07-2016)“…The impact of chronic musculoskeletal complaints (CMSC) and chronic widespread chronic musculoskeletal complaints (CWMSC) on mortality is controversial. The…”
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Causal relationships between migraine and microstructural white matter: a Mendelian randomization study
Published in Journal of headache and pain (16-02-2023)“…Background Migraine is a disabling neurological disorder with the pathophysiology yet to be understood. The microstructural alteration in brain white matter…”
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Migraine genetics: from genome-wide association studies to translational insights
Published in Genome medicine (19-08-2016)Get full text
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Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas
Published in Human genetics (01-04-2016)“…Migraine is a common disabling neurovascular brain disorder typically characterised by attacks of severe headache and associated with autonomic and…”
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